Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry

Label

Allophycocyanin (Excitation = 620-650 nm, Emission = 660-670 nm)

Antibody Source

Polyclonal Goat IgG
View all beta-Arrestin 2 Primary Antibodies »

Product Specifications

Immunogen

E. coli-derived recombinant human beta -Arrestin 2
Met1-Cys409
Accession # P32121

Specificity

Detects human beta -Arrestin 2 in direct ELISAs. In direct ELISAs, less than 1% cross-reactivity with recombinant human beta -Arrrestin 1 is observed.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for beta-Arrestin 2 Antibody [Allophycocyanin]

Application
Recommended Usage

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: beta-Arrestin 2

Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.

Alternate Names

ARB2, ARR2, ARRB2, betaArrestin 2

Gene Symbol

ARRB2

Additional beta-Arrestin 2 Products

Product Documents for beta-Arrestin 2 Antibody [Allophycocyanin]

Certificate of Analysis

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Product Specific Notices for beta-Arrestin 2 Antibody [Allophycocyanin]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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Associated Pathways

MAPK Signaling: Oxidative Stress Pathway MAPK Signaling: Oxidative Stress Pathway Thumbnail