BRCA1 Antibody (BRCA1/1472) [Allophycocyanin]

Novus Biologicals | Catalog # NBP2-54337APC

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Protein Array, CyTOF-ready

Label

Allophycocyanin (Excitation = 620-650 nm, Emission = 660-670 nm)

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # BRCA1/1472
View all BRCA1 Primary Antibodies »

Product Specifications

Immunogen

Recombinant fragment (around aa 445-620) of human BRCA1 protein (exact sequence is proprietary) (Uniprot: P38398)

Localization

Cytoplasmic and Nuclear

Marker

Breast Marker

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Applications for BRCA1 Antibody (BRCA1/1472) [Allophycocyanin]

Application
Recommended Usage

CyTOF-ready

Optimal dilutions of this antibody should be experimentally determined.

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Protein Array

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: BRCA1

The BRCA1 gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. BRCA1 is expressed in the cells of breast and other tissue, where it helps to repair double strand DNA breaks and initiate apoptosis in cells with excessive damage. BRCA1 mutations lead to improper DNA repair and eventually to cancer development.

BRCA1 antibodies are useful for cancer studies.

Long Name

Breast Cancer 1

Alternate Names

BRCAI, breast and ovarian cancer susceptibility protein 1, breast and ovarian cancer sususceptibility protein, breast cancer 1, early onset, breast cancer type 1 susceptibility protein, EC 6.3.2, EC 6.3.2.-, IRIS, PNCA4, PSCP, subunit 1

Gene Symbol

BRCA1

Additional BRCA1 Products

Product Documents for BRCA1 Antibody (BRCA1/1472) [Allophycocyanin]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for BRCA1 Antibody (BRCA1/1472) [Allophycocyanin]

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs

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