BRM Antibody (HMV337)

Novus Biologicals | Catalog # NBP3-48807

Recombinant Monoclonal Antibody
Novus Biologicals
100% Guarantee

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # HMV337
View all BRM Primary Antibodies »

Product Specifications

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human BRM. The exact sequence is proprietary.

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for BRM Antibody (HMV337)

BRM Antibody (HMV337)

Immunohistochemistry-Paraffin: BRM Antibody (HMV337) [NBP3-48807] -

IHC-P analysis of human muscle-invasive bladder cancer (MIBC) tissue using SMARCA2 antibody (HMV337)A strong SMARCA2 positivity of tumor cells.
BRM Antibody (HMV337)

Immunohistochemistry-Paraffin: BRM Antibody (HMV337) [NBP3-48807] -

IHC-P analysis of human anal canal squamous cell carcinoma (SCC) tissue using SMARCA2 antibody (HMV337)Squamous cell carcinoma with strong SMARCA2 immunostaining of tumor cells.
BRM Antibody (HMV337)

Immunohistochemistry-Paraffin: BRM Antibody (HMV337) [NBP3-48807] -

IHC-P analysis of human testis tissue using SMARCA2 antibody (HMV337).A distinct nuclear SMARCA2 staining in all intratubular cells except Sertoli cells.
BRM Antibody (HMV337)

Immunohistochemistry-Paraffin: BRM Antibody (HMV337) [NBP3-48807] -

IHC-P analysis of human warthin tumor (WT) from salivary gland tissue using SMARCA2 antibody (HMV337)Warthin tumor showing a strong SMARCA2 immunostaining of tumor cells.
BRM Antibody (HMV337)

Immunohistochemistry-Paraffin: BRM Antibody (HMV337) [NBP3-48807] -

IHC-P analysis of human high-grade serous ovarian cancer (HGSOC) tissue using SMARCA2 antibody (HMV337)A complete loss of SMARCA2 expression.
BRM Antibody (HMV337)

Immunohistochemistry-Paraffin: BRM Antibody (HMV337) [NBP3-48807] -

IHC-P analysis of human malignant melanoma from skin tissue using SMARCA2 antibody (HMV337). Malignant melanoma showing a faint SMARCA2 staining in only about 60% of tumor cells.

Applications for BRM Antibody (HMV337)

Application
Recommended Usage

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS, 2% BSA, 20% Glycerol

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: BRM

BRM is encoded by this gene is a member of the SWI/SNF family of proteins and is highly similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. Two transcript variants encoding different isoforms have been found for this gene, which contains a trinucleotide repeat (CAG) length polymorphism.

Long Name

Probable global transcription activator SNF2L2

Alternate Names

BAF190B, EC 3.6.4.-, hBRM, SMARCA2, SNF2-alpha, SNF2A, SNF2L2

Gene Symbol

SMARCA2

Additional BRM Products

Product Documents for BRM Antibody (HMV337)

Certificate of Analysis

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Product Specific Notices for BRM Antibody (HMV337)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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