Canine CTLA-4 (NP_001003106) VersaClone cDNA Summary
CTLA-4/CD152 (Cytotoxic T-Lymphocyte Antigen 4) is a transmembrane T cell inhibitory molecule that is expressed as a covalent homodimer. CTLA-4 is recruited from intracellular vesicles to the immunological synapse beginning 1-2 days after T cell activation. It forms a linear lattice with B7-1 on APC, inducing negative regulatory signals and ending CD28-dependent T cell activation. Mice deleted for CTLA-4 develop lethal autoimmune reactions due to continued T cell activation and poor control by regulatory T cells which constitutively express CTLA-4.
No product specific FAQs exist for this product, however you mayView all cDNA Clone FAQs
Reviews for Canine CTLA-4 (NP_001003106) VersaClone cDNA
There are currently no reviews for this product. Be the first to review Canine CTLA-4 (NP_001003106) VersaClone cDNA and earn rewards!
Have you used Canine CTLA-4 (NP_001003106) VersaClone cDNA?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image