Carboplatin

  ( 2 citations ) ( 1 Review )    
Product Datasheet
Catalog Number:2626
Alternate Names:NSC 241240, Paraplatin, JM 8
Chemical Name:cis-Diammine(1,1-cyclobutanedicarboxylato)platinum(II)
Product Details
Citations (2)
Reviews
Biological Activity
Antitumor agent that forms platinum-DNA adducts. Causes intra- and interstrand DNA crosslinks blocking DNA replication and transcription. Enhances radiation-induced single-strand DNA breakage and displays lower nephrotoxicity than analog cisplatin (Cat. No. 2251).
Technical Data
  • M.Wt:
    371.25
  • Formula:
    C6H12N2O4Pt
  • Solubility:
    Soluble to 25 mM in water
  • Purity:
    >99
  • Storage:
    Store at RT
  • CAS No:
    41575-94-4
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for Carboplatin include:

2 Citations: Showing 1 - 2
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  1. Multiparametric Cell Cycle Analysis Using the Operetta High-Content Imager and Harmony Software with PhenoLOGIC.
    Authors: Massey
    PLoS One  2015;10:e0134306
  2. Chk1 inhibition as a novel therapeutic strategy for treating triple-negative breast and ovarian cancers.
    Authors: Bryant Et al.
    Cell Death Differ  2014;14:570

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Average Rating: 4 (Based on 1 review)

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  Human Donghee Choi 01/04/2018
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Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

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