Chemical Name: cis-Diammine(1,1-cyclobutanedicarboxylato)platinum(II)
Biological Activity Antitumor agent that forms platinum-DNA adducts. Causes intra- and interstrand DNA crosslinks blocking DNA replication and transcription. Enhances radiation-induced single-strand DNA breakage and displays lower nephrotoxicity than analog cisplatin (Cat. No. 2251).
Soluble to 25 mM in water
Store at RT
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All Tocris products are intended for laboratory research use only.
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