CARS Antibody (CL2309) - BSA Free

Novus Biologicals | Catalog # NBP2-36757

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2B Clone # CL2309

Format

BSA Free
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Product Specifications

Immunogen

This antibody was developed using a recombinant protein derived from A8MVQ3, with the exact immunogen sequence remaining proprietary.

Reactivity Notes

Expected to cross react based on sequence identity: Mouse (86%), Rat (86%).

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Scientific Data Images for CARS Antibody (CL2309) - BSA Free

Immunohistochemistry: CARS Antibody (CL2309) [NBP2-36757]

Immunohistochemistry: CARS Antibody (CL2309) [NBP2-36757]

Immunohistochemistry: CARS Antibody (CL2309) [NBP2-36757] - Staining of human breast cancer shows cytoplasmic immunoreactivity in tumor cells.
Immunohistochemistry: CARS Antibody (CL2309) [NBP2-36757]

Immunohistochemistry: CARS Antibody (CL2309) [NBP2-36757]

Immunohistochemistry: CARS Antibody (CL2309) [NBP2-36757] - Staining of human skin shows strong cytoplasmic positivity in epidermis cells.
Immunohistochemistry: CARS Antibody (CL2309) [NBP2-36757]

Immunohistochemistry: CARS Antibody (CL2309) [NBP2-36757]

Immunohistochemistry: CARS Antibody (CL2309) [NBP2-36757] - Staining of human fallopian tube shows strong cytoplasmic immunoreactivity in glandular epithelium cells.
Immunohistochemistry: CARS Antibody (CL2309) [NBP2-36757]

Immunohistochemistry: CARS Antibody (CL2309) [NBP2-36757]

Immunohistochemistry: CARS Antibody (CL2309) [NBP2-36757] - Staining of human colon shows cytoplasmic immunoreactivity in both epithelial and lamina propria cells.
Immunohistochemistry: CARS Antibody (CL2309) [NBP2-36757]

Immunohistochemistry: CARS Antibody (CL2309) [NBP2-36757]

Immunohistochemistry: CARS Antibody (CL2309) [NBP2-36757] - Staining of human testis shows strong cytoplasmic positivity in seminiferous tubules.

Applications for CARS Antibody (CL2309) - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:2500 - 1:5000

Immunohistochemistry-Paraffin

1:2500-1:5000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CARS

CARS encodes a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. This gene is one of several located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq]

Alternate Names

CARS1, CysRS, cysteine translase, cysteine tRNA ligase 1, cytoplasmic, Cysteine--tRNA ligase, cysteinyl-tRNA synthetase, cysteinyl-tRNA synthetase, cytoplasmic, EC 6.1.1, EC 6.1.1.16, MGC:11246

Gene Symbol

CARS1

UniProt

Additional CARS Products

Product Documents for CARS Antibody (CL2309) - BSA Free

Certificate of Analysis

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Product Specific Notices for CARS Antibody (CL2309) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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