Caveolin-1 Antibody (RM325)

Novus Biologicals | Catalog # NBP2-77410

Recombinant Monoclonal Antibody
Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # RM325 expressed in HEK293
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Product Specifications

Immunogen

A peptide corresponding to the C-terminus of human Caveolin-1

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Caveolin-1 Antibody (RM325)

Western Blot: Caveolin-1 Antibody (RM325) [NBP2-77410]

Western Blot: Caveolin-1 Antibody (RM325) [NBP2-77410]

Western Blot: Caveolin-1 Antibody (RM325) [NBP2-77410] - HeLa cell lysate using anti-Caveolin-1 rabbit monoclonal antibody (Clone RM325) at a 1:40,000 dilution.
Immunohistochemistry-Paraffin: Caveolin-1 Antibody (RM325) [NBP2-77410]

Immunohistochemistry-Paraffin: Caveolin-1 Antibody (RM325) [NBP2-77410]

Immunohistochemistry-Paraffin: Caveolin-1 Antibody (RM325) [NBP2-77410] - Staining of human liver tissue section at a 1:1000 dilution.

Applications for Caveolin-1 Antibody (RM325)

Application
Recommended Usage

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 -1:1000

Western Blot

1:5000 - 1:40000

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

50% Glycerol/PBS, 1% BSA

Preservative

0.09% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Caveolin-1

Caveolae are specialized domains of the plasma membrane that are implicated in the sequestration of a variety of lipid and protein molecules. It has been suggested that these important cellular organelles have a pivotal role in such diverse biochemical processes as lipid metabolism, growth regulation, signal transduction, and apoptosis. Caveolin interacts with and regulates heterotrimeric G-proteins. Currently, there are three members of the caveolin multigene family which are known to encode 21-24 kDa integral membrane proteins that comprise the major structural component of the caveolar membrane in vivo. Caveolin-2 protein is abundantly expressed in fibroblasts and differentiated adipocytes, smooth and skeletal muscle, and endothelial cells. The expression of caveolin-1 is similar to that of caveolin-2 while caveolin-3 expression appears to be limited to muscle tissue types.

Alternate Names

CAV1, Caveolin1, MSTP085, VIP21

Gene Symbol

CAV1

Additional Caveolin-1 Products

Product Documents for Caveolin-1 Antibody (RM325)

Certificate of Analysis

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Product Specific Notices for Caveolin-1 Antibody (RM325)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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