CBL [p Ser669] Antibody (SR1097) - BSA Free

Novus Biologicals | Catalog # NBP3-21603

Recombinant Monoclonal Antibody
Novus Biologicals
100% Guarantee

Key Product Details

Validated by

Biological Validation

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1097 expressed in HEK293

Format

BSA Free
View all CBL Primary Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from human phospho-CBL [Ser669] (Uniprot #: P22681)

Modification

p Ser 669

Specificity

Detects endogenous levels of total phospho-CBL [Ser669]

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

120 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for CBL [p Ser669] Antibody (SR1097) - BSA Free

Western Blot: CBL [p Ser 669] Antibody (SR1097) [NBP3-21603] -

Western Blot: CBL [p Ser 669] Antibody (SR1097) [NBP3-21603] - Western blot analysis using NBP3-21603 in (1) HeLa cell lysate; (2) HeLa cell treated with pervanadate lysate.

Applications for CBL [p Ser669] Antibody (SR1097) - BSA Free

Application
Recommended Usage

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CBL

c-Cbl, product of c-cbl proto-oncogene, is a 120 kDa cytoplasmic protein involved in tyrosine kinase-dependent signaling pathways (1-3). c-Cbl is one of the earliest targets of tyrosine phosphorylation in response to a number of cellular stimuli. For instance, stimulation of growth factor receptors by EGF, PDGF, NGF and FGF, results in c-Cbl tyrosine phosphorylation, in lymphoid and other cell lines (4).

Long Name

Casitas B-lineage Lymphoma, E3 Ubiquitin Protein Ligase CBL

Alternate Names

CBL2, RNF55

Gene Symbol

CBL

Additional CBL Products

Product Documents for CBL [p Ser669] Antibody (SR1097) - BSA Free

Certificate of Analysis

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Product Specific Notices for CBL [p Ser669] Antibody (SR1097) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

E3 Ubiquitin Ligases

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FAQs

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Associated Pathways

Adipokines & Insulin Signaling Pathways Adipokines & Insulin Signaling Pathway Thumbnail