CBX3 Antibody - BSA Free

Novus Biologicals | Catalog # NBP1-83228

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Cited:

Mouse

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot, Immunocytochemistry/ Immunofluorescence

Cited:

IF/IHC

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all CBX3 Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: RVVNGKVEYFLKWKGFTDADNTWEPEENLDCPELIEAFLNSQKAGKEKDGTKRKSLSDSESDDSKSKKKRDAADKPRGFARGLDPERIIGATDSSGELMFLMKWKDSDEA

Reactivity Notes

Use in Mouse reported in scientific literature (PMID:35417713). Reactivity reported in scientific literature (PMID: 23409045).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CBX3 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: CBX3 Antibody [NBP1-83228]

Immunocytochemistry/ Immunofluorescence: CBX3 Antibody [NBP1-83228]

Immunocytochemistry/Immunofluorescence: CBX3 Antibody [NBP1-83228] - Staining of human cell line U-251 MG shows localization to nucleoplasm & nuclear bodies.
Immunohistochemistry-Paraffin: CBX3 Antibody [NBP1-83228]

Immunohistochemistry-Paraffin: CBX3 Antibody [NBP1-83228]

Immunohistochemistry-Paraffin: CBX3 Antibody [NBP1-83228] - Staining of human testis shows high expression.
CBX3 Antibody - BSA Free Immunohistochemistry-Paraffin: CBX3 Antibody - BSA Free [NBP1-83228]

Immunohistochemistry-Paraffin: CBX3 Antibody - BSA Free [NBP1-83228]

Staining of human duodenum shows strong nuclear positivity in glandular cells.
CBX3 Antibody - BSA Free Immunohistochemistry-Paraffin: CBX3 Antibody - BSA Free [NBP1-83228]

Immunohistochemistry-Paraffin: CBX3 Antibody - BSA Free [NBP1-83228]

Staining of human placenta shows strong nuclear positivity in trophoblastic cells.
CBX3 Antibody - BSA Free Immunohistochemistry-Paraffin: CBX3 Antibody - BSA Free [NBP1-83228]

Immunohistochemistry-Paraffin: CBX3 Antibody - BSA Free [NBP1-83228]

Staining of human lymph node shows strong nuclear positivity in germinal center cells.
CBX3 Antibody - BSA Free Western Blot: CBX3 Antibody - BSA Free [NBP1-83228]

Western Blot: CBX3 Antibody - BSA Free [NBP1-83228]

Analysis in human cell line SH-SY5Y.

Applications for CBX3 Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CBX3

HP1 gamma appears to be involved in transcriptional silencing in heterochromatin-like complexes. It recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. HP1 gamma may contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR) and involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.

Alternate Names

chromobox homolog 3, chromobox homolog 3 (Drosophila HP1 gamma), chromobox protein homolog 3, Drosophila), HECH, Heterochromatin protein 1 homolog gamma, heterochromatin protein HP1 gamma, heterochromatin-like protein 1, HP1 gamma, HP1 gamma homolog, HP1-GAMMA, Modifier 2 protein

Gene Symbol

CBX3

Additional CBX3 Products

Product Documents for CBX3 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for CBX3 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for CBX3 Antibody - BSA Free

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Protocols

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FAQs

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