CCDC88B Antibody - BSA Free

Novus Biologicals | Catalog # NBP1-88350

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all CCDC88B Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: GLRQEGPEHKPGPSEPSSVQLEEQEGPNQGLDLATGQAEAREHDQRLEGTVRDPAWQKPQQKSEGALEVQVWEGPIPGESLASGVAEQEALREEVAQLRRKAEALGDELEAQARKLEAQNTEAARLSKELAQ

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CCDC88B Antibody - BSA Free

Immunohistochemistry-Paraffin: CCDC88B Antibody [NBP1-88350]

Immunohistochemistry-Paraffin: CCDC88B Antibody [NBP1-88350]

Immunohistochemistry-Paraffin: CCDC88B Antibody [NBP1-88350] - Staining of human colon shows strong cytoplasmic positivity in lymphoid cells.
Immunohistochemistry-Paraffin: CCDC88B Antibody [NBP1-88350]

Immunohistochemistry-Paraffin: CCDC88B Antibody [NBP1-88350]

Immunohistochemistry-Paraffin: CCDC88B Antibody [NBP1-88350] - Staining of human skeletal muscle shows no positivity in myocytes as expected.
Immunohistochemistry-Paraffin: CCDC88B Antibody [NBP1-88350]

Immunohistochemistry-Paraffin: CCDC88B Antibody [NBP1-88350]

Immunohistochemistry-Paraffin: CCDC88B Antibody [NBP1-88350] - Staining of human lung shows strong cytoplasmic positivity in macrophages.
CCDC88B Antibody - BSA Free Immunohistochemistry-Paraffin: CCDC88B Antibody - BSA Free [NBP1-88350]

Immunohistochemistry-Paraffin: CCDC88B Antibody - BSA Free [NBP1-88350]

Staining of human lymph node shows strong cytoplasmic positivity in non-germinal center cells.

Applications for CCDC88B Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CCDC88B

CCDC88B, also known as Coiled-coil domain-containing protein 88B, has 6 isoforms, a 1476 amino acid isoform that is 165 kDa, a 1034 amino acid isoform that is 114 kDa, a 621 amino acid isoform that is 67 kDa, a 1358 amino acid isoform that is 151 kDa, 696 amino acid isoform that is 79 kDa, and a 139 amino acid isoform that is 15 kDa; and may be involved in linking organelles to microtubules. This protein has been associated with LPS-induced acute lung injury, cerulein induced chronic pancreatitis, Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema, and Smith-Lemli-Opitz syndrome. CCDC88B interacts with PLEKHA5, PBX2, MAP3K7 and GRP78 in signaling pathways.

Alternate Names

78 kDa glucose-regulated protein GRP78-interacting protein induced by ER stress, brain leucine zipper domain-containing protein, brain leucine zipper protein, CCDC88, coiled-coil domain containing 88B, coiled-coil domain-containing protein 88B, gipie, HKRP3, hook-related protein 3

Gene Symbol

CCDC88B

Additional CCDC88B Products

Product Documents for CCDC88B Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for CCDC88B Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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