CCL11/Eotaxin is a chemokine that interacts with CCR3 to induce eosinophil, basophil, dendritic cell, and Th2 cell chemoattraction during inflammatory and allergic reactions. Its production is upregulated in airway epithelium, alveolar macrophages, eosinophils, smooth muscle cells, chondrocytes, and fibroblasts following allergen or inflammatory challenge. CCL11 is also involved in the growth of myeloid cell progenitors and the differentiation of mast cells.
CCL11/Eotaxin Antibody (C1) - BSA Free
Novus Biologicals | Catalog # NBP3-41065
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Key Product Details
Species Reactivity
Human
Applications
ELISA
Label
Unconjugated
Antibody Source
Monoclonal Mouse IgG1 kappa Clone # C1
Format
BSA Free
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Product Specifications
Immunogen
Immunized with recombinant Human CCL11/Eotaxin (Uniprot#: Q6I9T4; Gly24-Pro97 (Uniprot#: Q6I9T4)
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1 kappa
Applications for CCL11/Eotaxin Antibody (C1) - BSA Free
Application
Recommended Usage
ELISA
Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified
Formulation
PBS, pH7.4, 50% glycerol
Format
BSA Free
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Background: CCL11/Eotaxin
Alternate Names
Eotaxin
Gene Symbol
CCL11
Additional CCL11/Eotaxin Products
Product Documents for CCL11/Eotaxin Antibody (C1) - BSA Free
Certificate of Analysis
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Product Specific Notices for CCL11/Eotaxin Antibody (C1) - BSA Free
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
Related Research Areas
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Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
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- Sandwich ELISA (Colorimetric) – Biotin/Streptavidin Detection Protocol
- Sandwich ELISA (Colorimetric) – Direct Detection Protocol
- Troubleshooting Guide: ELISA
- View all Protocols, Troubleshooting, Illustrated assays and Webinars
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