CCL2/JE/MCP-1 Antibody (11k2) [Alexa Fluor™ Plus 555] - Chimeric

Name: CCL2/JE/MCP-1 Antibody (11k2) [Alexa Fluor™ Plus 555] - Chimeric
Brand: Novus Biologicals
SKU: NBP3-45119AFP555
Price: 759 USD
Availability: InStock

Novus Biologicals | Catalog # NBP3-45119AFP555

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Product Documents

Recombinant Monoclonal Antibody

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Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Human, Mouse

Applications

ELISA, Block/Neutralize

Label

Alexa Fluor Plus 555

Antibody Source

Recombinant Monoclonal Rabbit IgG Kappa Clone # 11k2

View all CCL2/JE/MCP-1 Primary Antibodies »

Product Specifications

Immunogen

Human CCL2/JE/MCP-1

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG Kappa

Applications for CCL2/JE/MCP-1 Antibody (11k2) [Alexa Fluor™ Plus 555] - Chimeric

Application

Recommended Usage

Block/Neutralize

Optimal dilutions of this antibody should be experimentally determined.

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: CCL2/JE/MCP-1

CCL2/JE/MCP-1, is a chemokine that binds the receptor CCR2 and induces the chemoattraction of mononuclear cells. It induces the activation of monocytes, NK cells, lymphocytes, and basophils. Additionally, CCL2 promotes Th2 polarization in CD4⁺ T cells, and CCL2-mediated recruitment of monocytes to sites of inflammation contributes to disease severity in atherosclerosis, multiple sclerosis, and allergic asthma. Endogenous proteolytic trimming of CCL2 at the N-terminus, including the N-terminal pyrrolidone carboxylic acid-modified glutamine, downregulates activity but not receptor binding.

Alternate Names

GDCF-2, HC11, HSMCR30, MCAF, MCP-1, SMC-CF

Gene Symbol

CCL2

Additional CCL2/JE/MCP-1 Products

Product Documents for CCL2/JE/MCP-1 Antibody (11k2) [Alexa Fluor™ Plus 555] - Chimeric

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Certificate of Analysis

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Product Specific Notices for CCL2/JE/MCP-1 Antibody (11k2) [Alexa Fluor™ Plus 555] - Chimeric

This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.