CD11c Antibody - BSA Free

Novus Biologicals | Catalog # NB110-55523

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Primate (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
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Product Specifications

Immunogen

Synthetic 15 amino acid peptide from internal region of human CD11c.

Epitope

Internal domain of human

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (87%), Marmoset (80%).

Marker

Dendritic Cell Marker

Specificity

Human CD11c. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for CD11c Antibody - BSA Free

Immunohistochemistry-Paraffin: CD11c Antibody - BSA Free [NB110-55523]

Immunohistochemistry-Paraffin: CD11c Antibody - BSA Free [NB110-55523]

Immunohistochemistry-Paraffin: CD11c Antibody - BSA Free [NB110-55523] - Analysis of anti-CD11c antibody with human prostate at dilution 10-20 ug/ml.

Applications for CD11c Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

5 - 10 ug/ml
Application Notes
.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.1% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: CD11c

ITGAX encodes the integrin alpha X chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 seems to broadly overlap the properties of the alpha M beta 2 integrin in adherence of neutrophils and monocytes to stimulated endothelium, and the phagocytosis of complement coated particles.

Alternate Names

CD11c, Integrin alpha X, ITGAX, p150,95 alpha

Entrez Gene IDs

3687 (Human)

Gene Symbol

ITGAX

Additional CD11c Products

Product Documents for CD11c Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for CD11c Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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