Centaurin alpha 1 Antibody

Novus Biologicals | Catalog # NB300-907

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat, Porcine

Predicted:

Canine (100%). Backed by our 100% Guarantee.

Applications

Western Blot, Peptide ELISA

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG
View all Centaurin alpha 1 Primary Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-QEYAVEAHFKHKP corresponding to C-Terminus according to NP_006860.1.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for Centaurin alpha 1 Antibody

Western Blot: Centaurin alpha 1 Antibody [NB300-907]

Western Blot: Centaurin alpha 1 Antibody [NB300-907]

Western Blot: Centaurin alpha 1 Antibody [NB300-907] - Staining of Human Cerebellum (A), Mouse (B), Rat (C) and Pig (D) Brain lysates (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for Centaurin alpha 1 Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:32000

Western Blot

1 - 3 ug/ml
Application Notes
WB: Approx. 40 kDa band observed in human brain and mouse brain lysates (calculated MW of 43.4 kDa band according to NP_006860).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Centaurin alpha 1

The centaurin alpha 1 protein is a high affinity PtdIns(3,4,5)P3 binding protein enriched in brain. By acting as a GTPase activating protein for ADP ribosylation factor 6 (ARF6), centaurin alpha 1 is able to switch off ARF6 and inhibit its ability to mediate beta 2 adrenoceptor internalization and negatively regulates ARF6 activity by functioning as an in vivo PIP3 dependent ARF6 GAP.

Alternate Names

arf-GAP with dual PH domain-containing protein 1, ArfGAP with dual PH domains 1, CENTA1centaurin-alpha-1, centaurin, alpha 1, centaurin-alpha, Centaurin-alpha-1, Cnt-a1, GCS1L, p42IP4, Putative MAPK-activating protein PM25

Entrez Gene IDs

11033 (Human); 231821 (Mouse); 171097 (Rat)

Gene Symbol

ADAP1

UniProt

NP_006860. (Human)

Additional Centaurin alpha 1 Products

Product Documents for Centaurin alpha 1 Antibody

Certificate of Analysis

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Product Specific Notices for Centaurin alpha 1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for Centaurin alpha 1 Antibody

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