Cystic fibrosis transmembrane conductance regulator (CFTR) is a multi-pass transmembrane protein that functions as a chloride channel. CFTR belongs to the ATP-binding cassette (ABC) superfamily. Mutations in CFTR cause the pulmonary disease, cystic fibrosis (CF). Specifically, deletion of phenyalanine at position 508 (DeltaF508-CFTR) results in a folding defect which impairs chloride channel function. The mechanism by which channel dysfunction relates to disease symptoms is a focus of intense research. CFTR dysfunction results in disruption of ion transport and subsequent blockage of airways by secreted mucus. CFTR may also play a role in the skeletal muscle atrophy and dysfunction that characterizes CF. In addition, CFTR-mediated chloride secretion underlies fluid accumulation and cyst growth in autosomal dominant polycystic kidney disease (ADPKD).
Porcine CFTR ELISA Kit (Colorimetric)
Novus Biologicals | Catalog # NBP3-50069
Product Specifications
Assay Type
Kit Type
Species
Description
Precision
Intra-Assay Precision (Precision within an assay) CV% 10
Inter-Assay Precision (Precision between assays) CV% 10
Recovery for Porcine CFTR ELISA Kit (Colorimetric)
Recovery
Linearity
Scientific Data Images for Porcine CFTR ELISA Kit (Colorimetric)
ELISA: Porcine CFTR ELISA Kit (Colorimetric) [NBP3-50069]
Standard Curve Reference.Kit Contents for Porcine CFTR ELISA Kit (Colorimetric)
- Biotinylated Detection Ab Diluent
- Certificate of Analysis
- Concentrated Biotinylated Detection Ab (100x)
- Concentrated HRP Conjugate (100x)
- Concentrated Wash Buffer (25x)
- HRP Conjugate Diluent
- Micro ELISA Plate (Dismountable)
- Plate Sealer
- Product Description
- Reference Standard
- Reference Standard & Sample Diluent
- Stop Solution
- Substrate Reagent
Preparation and Storage
Shipping
Stability & Storage
Background: CFTR
Long Name
Alternate Names
Gene Symbol
Additional CFTR Products
Product Documents for Porcine CFTR ELISA Kit (Colorimetric)
Certificate of Analysis
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Product Specific Notices for Porcine CFTR ELISA Kit (Colorimetric)
This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.
Related Research Areas
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Protocols
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- Sandwich ELISA (Colorimetric) – Biotin/Streptavidin Detection Protocol
- Sandwich ELISA (Colorimetric) – Direct Detection Protocol
- Troubleshooting Guide: ELISA
- View all Protocols, Troubleshooting, Illustrated assays and Webinars
Associated Pathways
