cGK2/PRKG2 Antibody - BSA Free

Novus Biologicals | Catalog # NBP1-84497

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (96%), Rat (96%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all cGK2/PRKG2 Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: REYHLKELREQLSKQTVAIAELTEELQNKCIQLNKLQDVVHMQGGSPLQASPDKVPLEVHRKTSGLVSLHSRRGAKAGVSAEPTTRTYDLNKPPEFSFEKARVRKDSSEKKLITDALNKNQFLKRLDPQQIKDMVE

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for cGK2/PRKG2 Antibody - BSA Free

cGK2/PRKG2 Antibody - BSA Free Immunohistochemistry-Paraffin: cGK2/PRKG2 Antibody - BSA Free [NBP1-84497]

Immunohistochemistry-Paraffin: cGK2/PRKG2 Antibody - BSA Free [NBP1-84497]

Staining of human skeletal muscle shows moderate to strong cytoplasmic positivity in myocytes.
cGK2/PRKG2 Antibody - BSA Free Immunohistochemistry-Paraffin: cGK2/PRKG2 Antibody - BSA Free [NBP1-84497]

Immunohistochemistry-Paraffin: cGK2/PRKG2 Antibody - BSA Free [NBP1-84497]

Staining of human small intestine shows strong cytoplasmic positivity in glandular cells.
cGK2/PRKG2 Antibody - BSA Free Immunohistochemistry-Paraffin: cGK2/PRKG2 Antibody - BSA Free [NBP1-84497]

Immunohistochemistry-Paraffin: cGK2/PRKG2 Antibody - BSA Free [NBP1-84497]

Staining of human lymph node shows strong cytoplasmic positivity in non-germinal center cells.
cGK2/PRKG2 Antibody - BSA Free Immunohistochemistry-Paraffin: cGK2/PRKG2 Antibody - BSA Free [NBP1-84497]

Immunohistochemistry-Paraffin: cGK2/PRKG2 Antibody - BSA Free [NBP1-84497]

Staining of human cerebral cortex shows strong cytoplasmic positivity in neurons.

Applications for cGK2/PRKG2 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: cGK2/PRKG2

cGK2/PRKG2, also known as cGMP-dependent protein kinase 2, is 762 amino acids long and approximately 87kDa. cGK2/PRKG2 is a protein kinase that is highly expressed in the brain, intestine and lung. Current research surrounding cGK2/PRKG2 has shown a potential link with several disorders and diseases including cystic fibrosis, gout, malaria, lung cancer, alcoholism, diarrhea, and hyperphenylalaninemia. cGK2/PRKG2 may also interact with PTS, LASP1, YWHAB, MYLK, and PLCB3 in pathways such as cGMP signaling, platelet homeostasis, EDNRB signaling, signaling in gap junctions, nitric oxide metabolism, and eNOS activation and regulation.

Long Name

cGMP-dependent protein kinase 2

Alternate Names

cGK 2, cGK2, cGKII, PRKG2, PRKGR2

Gene Symbol

PRKG2

Additional cGK2/PRKG2 Products

Product Documents for cGK2/PRKG2 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for cGK2/PRKG2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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