CGP 74514 dihydrochloride

Catalog # Availability Size / Price Qty
5472/10
5472/50
Cat.No. 5472 - CGP 74514 dihydrochloride | C19H24ClN7.2HCl
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Description: Potent cdk1 inhibitor

Chemical Name: rel-N2-[(1R,2S)-2-Aminocyclohexyl]-N6-(3-chlorophenyl)-9-ethyl-9H-purine-2,6-diamine dihydrochloride

Product Details
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Biological Activity

Potent cdk1 inhibitor (IC50 = 25 nM). Reduces Akt phosphorylation and increases mitochondrial damage in leukemia cells in vitro in combination with LY 294002.

Technical Data

Formula:
C19H24ClN7.2HCl
Solubility:
Soluble to 50 mM in water and to 100 mM in DMSO
Storage:
Store the unopened product at room temperature. Do not use past expiration date.

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

Product Datasheets

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