7 results for "CDK1 Subfamily Inhibitors" in Products
CDK1 Subfamily Inhibitors
The CDK1 subfamily of cyclin-dependent kinases includes CDK1, CDK2 and CDK3. All three members of this family can bind cyclin A, cyclin B, cyclin E and possibly cyclin C, and are fundamentally involved in regulation of the cell cycle.
CDK1
CDK1 is a 34kDa protein that is highly conserved and is essential for cell cycle progression in mammals. The roles of CDK2 and CDK3 in the cell cycle are dispensable as CDK1 can interact with multiple different cyclins to compensate if CDK2 and/or CDK3 are ...
Cdk1 inhibitor
| Chemical Name: | 5-(6-Quinolinylmethylene)-2-[(2-thienylmethyl)amino]-4(5H)-thiazolone |
| Purity: | ≥98% |
Cdk2 inhibitor; also potent inhibitor of aurora kinase A and B
| Chemical Name: | 4-[[6-(Cyclohexylmethoxy)-1H-purin-2-yl]amino]-N,N-diethylbenzamide |
| Purity: | ≥98% |
Potent CDK1 inhibitor
| Chemical Name: | rel-N2-[(1R,2S)-2-Aminocyclohexyl]-N6-(3-chlorophenyl)-9-ethyl-9H-purine-2,6-diamine dihydrochloride |
| Purity: | ≥98% |
Potent CDK2 inhibitor
| Alternate Names: | AUZ 454 |
| Chemical Name: | N-[4-[(2-Amino-4-pyrimidinyl)oxy]phenyl]-N'-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]urea |
| Purity: | ≥98% |
SKP2 (S-phase kinase-associated protein 2) inhibitor; upregulates p27 and arrests cell cycle in G1 phase
| Chemical Name: | N-(4-Butyl-2-methylphenyl)acetamide |
| Purity: | ≥98% |
Potent and selective inhibitor of CDK2, CDK5, CDK1 and CDK9
| Alternate Names: | SCH 727965 |
| Chemical Name: | (2S)-1-[3-Ethyl-7-[[(1-oxido-3-pyridinyl)methyl]amino]pyrazolo[1,5-a]pyrimidin-5-yl]-2-piperidineethanol |
| Purity: | ≥98% |
Potent and selective PKMYT1 inhibitor
| Alternate Names: | Lunresertib |
| Chemical Name: | (S)-2-Amino-1-(3-hydroxy-2,6-dimethylphenyl)-5,6-dimethylpyrrolo[2,3-b]pyridine-3-carboxamide |
| Purity: | ≥98% |
