Hydrochloride salt of CHIR 99021
(Cat. No. 4423), a highly selective GSK-3 inhibitor.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
AKT kinase activity is required for lithium to modulate mood-related behaviors in mice.
Pan et al.
Selective glycogen synthase kinase 3 inhibitors potentiate insulin activation of glucose transport and utilization in vitro and in vivo.
Ring et al.
Pleiotropy of glycogen synthase kinase-3 inhibition by CHIR99021 promotes self-renewal of embyronic stem cells from refractory mouse strains.
Ye et al.
PLoS One, 2012;7:e35892