Catalog Number: 2490
Alternate Names: Plavix
Chemical Name: Methyl 2-(4,5,6,7-tetrahydrothieno[3,2-c]pyridin-5-yl)-2-(2-chlorophenyl)acetate hydrochloride
Biological Activity
Selective, high affinity P2Y12 receptor antagonist (pKi = 6.9 for hP2Y12 receptor). Inhibits ADP-induced platelet aggregation; potent antithrombotic agent. Requires bioactivation, unlike PSB 0739.

Active Enantiomer also available.

Technical Data
  • M.Wt:
    358.28
  • Formula:
    C16H16NO2SCl.HCl
  • Solubility:
    Soluble to 100 mM in DMSO and to 100 mM in ethanol
  • Purity:
    >99%
  • Storage:
    Desiccate at +4°C
  • CAS No:
    130209-90-4
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Other Product-Specific Information:
Background References
  1. Pharmacological profiles of cloned mammalian P2Y-receptor subtypes.
    Kugelgen
    Pharmacol.Ther., 2006;110:415
  2. P2Y12, a new platelet ADP receptor, target of clopidogrel.
    Savi et al.
    Biochem.Biophys.Res.Comm., 2001;283:379

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