CNP belongs to the natriuretic peptide hormone family which also includes ANP and BNP. CNP modulates cGMP-mediated proliferation and differentiation in a wide variety of tissues through interactions with its receptor, ANPRB. CNP promotes vasorelaxation and vascular remodeling. It is upregulated in damaged vascular endothelium.
CNP/NPPC Antibody (462608) [DyLight 350]
Novus Biologicals | Catalog # FAB31271D
Key Product Details
Species Reactivity
Human
Applications
Western Blot
Label
DyLight 350 (Excitation = 353 nm, Emission = 432 nm)
Antibody Source
Monoclonal Rat IgG2B Clone # 462608
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Product Specifications
Immunogen
E. coli-derived recombinant human CNP
Lys24-Cys126
Accession # P23582
Lys24-Cys126
Accession # P23582
Specificity
Detects human pro-CNP and mature CNP53 and CNP29 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) ANP or rhBNP is observed.
Clonality
Monoclonal
Host
Rat
Isotype
IgG2B
Description
This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label.
For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.
For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.
Applications for CNP/NPPC Antibody (462608) [DyLight 350]
Application
Recommended Usage
Western Blot
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Recommended applications are based on validated applications from the unconjugated base product MAB31271. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols.
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Formulation
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: CNP
Long Name
C-type Natriuretic Peptide
Alternate Names
NPPC
Gene Symbol
NPPC
Additional CNP Products
Product Documents for CNP/NPPC Antibody (462608) [DyLight 350]
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for CNP/NPPC Antibody (462608) [DyLight 350]
DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
Related Research Areas
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Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
- Cellular Response to Hypoxia Protocols
- R&D Systems Quality Control Western Blot Protocol
- Troubleshooting Guide: Western Blot Figures
- Western Blot Conditions
- Western Blot Protocol
- Western Blot Protocol for Cell Lysates
- Western Blot Troubleshooting
- Western Blot Troubleshooting Guide
- View all Protocols, Troubleshooting, Illustrated assays and Webinars
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