CometAssay Single Cell Gel Electrophoresis Assay

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Product Details
Citations (318)

CometAssay Single Cell Gel Electrophoresis Assay Summary

Includes twenty-five specially treated CometSlides (2 Well) and sufficient reagents for 50 test samples.

Key Benefits

• Specially treated slides to promote agarose adherence
• Ready to use low melt agarose (LMAgarose) in convenient size
• Lysis Solution suitable for either alkaline or neutral comet assay
• Optimized electrophoresis conditions

Product Specifications

  • Applicable for the analysis of either single- or double-strand DNA breaks
  • Study cellular responses to DNA damage
  • Screen for inhibitors of DNA repair
  • Test chemicals for toxicity
  • Screen for environmental mutagens

What is the CometAssay?

The Comet assay, or single cell gel electrophoresis assay, provides a simple and effective method for evaluating DNA damage in cells. The principle of the assay is based upon the ability of denatured, cleaved DNA fragments to migrate out of the nucleoid under the influence of an electric field, whereas undamaged DNA migrates slower and remains within the confines of the nucleoid when a current is applied. Evaluation of the DNA “comet” tail shape and migration pattern allows for assessment of DNA damage. The general Comet assay protocol includes first immobilizing cells in a bed of low melting point agarose, gently lysing the cells, treating cells with neutral or alkali solutions to unwind and denature the DNA as well as hydrolyze sites of damage. DNA is then subjected to electrophoresis and stained with a fluorescent DNA intercalating dye.

Kit Contents

• CometAssay Lysis Solution
• CometAssay LMAgarose
• CometSlides (2 Well, 25 Slides)
• 200 mM EDTA, pH 10


Shipping Conditions
The product is shipped ambient or with polar packs. Upon receipt, store it immediately at the temperature recommended on the product label.
Store products immediately at the temperature recommended on the product labels.


For research use only. Not for diagnostic use.

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Citations for CometAssay Single Cell Gel Electrophoresis Assay

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

318 Citations: Showing 1 - 10
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  1. Compartmentalized regulation of NAD+ by Di (2-ethyl-hexyl) phthalate induces DNA damage in placental trophoblast
    Authors: S Zhao, Y Hong, YY Liang, XL Li, JC Shen, CC Sun, LL Chu, J Hu, H Wang, DX Xu, SC Zhang, DD Xu, T Xu, LL Zhao
    Redox Biology, 2022;55(0):102414.  2022
  2. Translesion DNA synthesis mediates acquired resistance to olaparib plus temozolomide in small cell lung cancer
    Authors: M Stanzione, J Zhong, E Wong, TJ LaSalle, JF Wise, A Simoneau, DT Myers, S Phat, M Sade-Feldm, MS Lawrence, MK Hadden, L Zou, AF Farago, NJ Dyson, BJ Drapkin
    Science Advances, 2022;8(19):eabn1229.  2022
  3. The Salutary Effects of Catalpol on Diesel Exhaust Particles-Induced Thrombogenic Changes and Cardiac Oxidative Stress, Inflammation and Apoptosis
    Authors: A Nemmar, S Beegam, NE Zaaba, S Alblooshi, S Alseiari, BH Ali
    Biomedicines, 2022;10(1):.  2022
  4. The human ion channel TRPM2 modulates cell survival in neuroblastoma through E2F1 and FOXM1
    Authors: I Hirschler-, F Festa, S Huang, GL Moldovan, C Nicolae, A Dhoonmoon, L Bao, K Keefer, SJ Chen, HG Wang, JY Cheung, BA Miller
    Scientific Reports, 2022;12(1):6311.  2022
  5. SF3B1 homeostasis is critical for survival and therapeutic response in T cell leukemia
    Authors: C Han, A Khodadadi-, AH Lorch, Q Jin, V Serafin, P Zhu, Y Politanska, L Sun, BT Gutierrez-, MV Pryzhkova, H Abdala-Val, ET Bartom, B Buldini, G Basso, SE Velu, K Sarma, BB Mattamana, BK Cho, RC Obeng, YA Goo, PW Jordan, A Tsirigos, Y Zhou, P Ntziachris
    Science Advances, 2022;8(3):eabj8357.  2022
  6. Lamin B1 deletion in myeloid neoplasms causes nuclear anomaly and altered hematopoietic stem cell function
    Authors: A Reilly, J Philip Cre, S Stewart, MC Stolla, Y Wang, J Du, R Wellington, S Busch, EH Estey, PS Becker, M Fang, SB Keel, JL Abkowitz, LA Soma, J Ma, Z Duan, S Doulatov
    Cell Stem Cell, 2022;0(0):.  2022
  7. Targeted CUL4A inhibition synergizes with cisplatin to yield long-term survival in models of head and neck squamous cell carcinoma through a DDB2-mediated mechanism
    Authors: TM Jones, CM Espitia, A Ooi, JE Bauman, JS Carew, ST Nawrocki
    Cell Death & Disease, 2022;13(4):350.  2022
  8. Assessment of the ameliorative effect of curcumin on pendimethalin-induced genetic and biochemical toxicity
    Authors: A Acar, D Singh, AK Srivastava
    Scientific Reports, 2022;12(1):2195.  2022
  9. Hesperadin suppresses pancreatic cancer through ATF4/GADD45A axis at nanomolar concentrations
    Authors: Y Zhang, J Wu, Y Fu, R Yu, H Su, Q Zheng, H Wu, S Zhou, K Wang, J Zhao, S Shen, G Xu, L Wang, C Yan, X Zou, Y Lv, S Zhang
    Oncogene, 2022;0(0):.  2022
  10. Cytotoxicity, crosslinking and biological activity of three mitomycins
    Authors: SY Cheng, L Delgado-Cr, CC Clement, O Zacarias, M Concheiro-, N Towler, T Snyder, M Zheng, N Almodovar, C Gonzalez, M Romaine, AM Sapse, E Champeil
    Bioorganic chemistry, 2022;123(0):105744.  2022
  11. RNase H2, mutated in Aicardi-Gouti�res syndrome, resolves co-transcriptional R-loops to prevent DNA breaks and inflammation
    Authors: A Cristini, M Tellier, F Constantin, C Accalai, LO Albulescu, R Heiringhof, N Bery, O Sordet, S Murphy, N Gromak
    Nature Communications, 2022;13(1):2961.  2022
  12. Chronic arsenic exposure suppresses ATM pathway activation in human keratinocytes
    Authors: AN Nail, LM McCaffrey, M Banerjee, AP Ferragut C, JC States
    Toxicology and Applied Pharmacology, 2022;446(0):116042.  2022
  13. Reducing Chemotherapy-Induced DNA Damage via nAChR-Mediated Redox Reprograming-A New Mechanism for SCLC Chemoresistance Boosted by Nicotine
    Authors: Y Wang, T Bian, L Song, Y Jiang, Z Huo, RG Salloum, GW Warren, FJ Kaye, N Fujioka, L Jin, C Xing
    Cancers, 2022;14(9):.  2022
  14. Effective Radiosensitization of Bladder Cancer Cells by Pharmacological Inhibition of DNA-PK and ATR
    Authors: AA Chughtai, J Pannhausen, P Dinger, J Wirtz, R Knüchel, NT Gaisa, MJ Eble, M Rose
    Biomedicines, 2022;10(6):.  2022
  15. Multinucleated Retinal Pigment Epithelial Cells Adapt to Vision and Exhibit Increased DNA Damage Response
    Authors: Q Ke, L Gong, X Zhu, R Qi, M Zou, B Chen, W Liu, S Huang, Y Liu, DW Li
    Cells, 2022;11(9):.  2022
  16. Use of CRISPR/Cas9 with homology-directed repair to silence the human topoisomerase IIalpha intron-19 5' splice site: Generation of etoposide resistance in human leukemia K562 cells
    Authors: VA Hernandez, J Carvajal-M, X Wang, M Pietrzak, JC Yalowich, TS Elton
    PLoS ONE, 2022;17(5):e0265794.  2022
  17. Combination of chemotherapy with BRAF inhibitors results in effective eradication of malignant melanoma by preventing ATM-dependent DNA repair
    Authors: J Alonso-Mar, A Villanueva, JM Piulats, M Martínez-I, L Solé, J Martín-Lib, S Segura, RM Pujol, M Iglesias, A Bigas, F Gallardo, L Espinosa
    Oncogene, 2021;0(0):.  2021
  18. USP9X-mediated KDM4C deubiquitination promotes lung cancer radioresistance by epigenetically inducing TGF-&beta2 transcription
    Authors: X Jie, WP Fong, R Zhou, Y Zhao, Y Zhao, R Meng, S Zhang, X Dong, T Zhang, K Yang, G Wu, S Xu
    Cell Death and Differentiation, 2021;0(0):.  2021
  19. WD repeat domain 5 promotes chemoresistance and Programmed Death-Ligand 1 expression in prostate cancer
    Authors: Q Zhou, X Chen, H He, S Peng, Y Zhang, J Zhang, L Cheng, S Liu, M Huang, R Xie, T Lin, J Huang
    Theranostics, 2021;11(10):4809-4824.  2021
  20. Melanoma subpopulations that rapidly escape MAPK pathway inhibition incur DNA damage and rely on stress signalling
    Authors: C Yang, C Tian, TE Hoffman, NK Jacobsen, SL Spencer
    Nature Communications, 2021;12(1):1747.  2021
  21. PRPF19 regulates p53-dependent cellular senescence by modulating alternative splicing of MDM4 mRNA
    Authors: K Yano, RU Takahashi, B Shiotani, J Abe, T Shidooka, Y Sudo, Y Yamamoto, S Kan, H Sakagami, H Tahara
    The Journal of Biological Chemistry, 2021;297(1):100882.  2021
  22. PARylation prevents the proteasomal degradation of topoisomerase I DNA-protein crosslinks and induces their deubiquitylation
    Authors: Y Sun, J Chen, SN Huang, YP Su, W Wang, K Agama, S Saha, LM Jenkins, JM Pascal, Y Pommier
    Nature Communications, 2021;12(1):5010.  2021
  23. Replication Stress Response Modifies Sarcomeric Cardiomyopathy Remodeling
    Authors: S Pal, BR Nixon, MS Glennon, P Shridhar, SL Satterfiel, YR Su, JR Becker
    Journal of the American Heart Association, 2021;10(15):e021768.  2021
  24. Multi-platform profiling characterizes molecular subgroups and resistance networks in chronic lymphocytic leukemia
    Authors: J Bloehdorn, A Braun, A Taylor-Wei, BMC Jebaraj, S Robrecht, J Krzykalla, H Pan, A Giza, G Akylzhanov, K Holzmann, A Scheffold, HE Johnston, RF Yeh, T Klymenko, E Tausch, B Eichhorst, L Bullinger, K Fischer, M Weisser, T Robak, C Schneider, J Gribben, LN Dahal, MJ Carter, O Elemento, DA Landau, DS Neuberg, MS Cragg, A Benner, M Hallek, CJ Wu, H Döhner, S Stilgenbau, D Mertens
    Nature Communications, 2021;12(1):5395.  2021
  25. The prolyl-isomerase PIN1 is essential for nuclear Lamin-B structure and function and protects heterochromatin under mechanical stress
    Authors: F Napoletano, G Ferrari Br, IAP Voto, A Santin, L Celora, E Campaner, C Dezi, A Bertossi, E Valentino, M Santorsola, A Rustighi, V Fajner, E Maspero, F Ansaloni, V Cancila, CF Valenti, M Santo, OB Artimagnel, S Finaurini, U Gioia, S Polo, R Sanges, C Tripodo, A Mallamaci, S Gustincich, F d'Adda di, F Mantovani, V Specchia, G Del Sal
    Cell Reports, 2021;36(11):109694.  2021
  26. Exosome-derived microRNA-433 inhibits tumorigenesis through incremental infiltration of CD4 and CD8 cells in non-small cell lung cancer
    Authors: B Liu, R Zhang, Y Zhu, R Hao
    Oncology Letters, 2021;22(2):607.  2021
  27. Targeting lactate dehydrogenase a improves radiotherapy efficacy in non-small cell lung cancer: from bedside to bench
    Authors: Y Yang, Y Chong, M Chen, W Dai, X Zhou, Y Ji, G Qiu, X Du
    Journal of Translational Medicine, 2021;19(1):170.  2021
  28. VDAC1 oligomerization may enhance DDP-induced hepatocyte apoptosis by exacerbating oxidative stress and mitochondrial DNA damage
    Authors: X Zhu, L Luo, Y Xiong, N Jiang, Y Wang, Y Lv, Y Xie
    FEBS Open Bio, 2021;0(0):.  2021
  29. Glycoprotein PTGDS promotes tumorigenesis of diffuse large B-cell lymphoma by MYH9-mediated regulation of Wnt-beta-catenin-STAT3 signaling
    Authors: S Hu, S Ren, Y Cai, J Liu, Y Han, Y Zhao, J Yang, X Zhou, X Wang
    Cell Death and Differentiation, 2021;0(0):.  2021
  30. Modulation of pancreatic cancer cell sensitivity to FOLFIRINOX through microRNA-mediated regulation of DNA damage
    Authors: P Carotenuto, F Amato, A Lampis, C Rae, S Hedayat, MC Previdi, D Zito, M Raj, V Guzzardo, F Sclafani, A Lanese, C Parisi, C Vicentini, I Said-Hunti, JC Hahne, A Hallsworth, V Kirkin, K Young, R Begum, A Wotherspoo, K Kouvelakis, SX Azevedo, V Michalarea, R Upstill-Go, S Rao, D Watkins, N Starling, A Sadanandam, DK Chang, AV Biankin, NB Jamieson, A Scarpa, D Cunningham, I Chau, P Workman, M Fassan, N Valeri, C Braconi
    Nature Communications, 2021;12(1):6738.  2021
  31. Genomic aberrations after short-term exposure to colibactin-producing E. coli transform primary colon epithelial cells
    Authors: A Iftekhar, H Berger, N Bouznad, J Heuberger, F Boccellato, U Dobrindt, H Hermeking, M Sigal, TF Meyer
    Nature Communications, 2021;12(1):1003.  2021
  32. AMPK-mediated phosphorylation on 53BP1 promotes c-NHEJ
    Authors: Y Jiang, Y Dong, Y Luo, S Jiang, FL Meng, M Tan, J Li, Y Zang
    Cell Reports, 2021;34(7):108713.  2021
  33. Disruption of nucleocytoplasmic trafficking as a cellular senescence driver
    Authors: JH Park, SJ Ryu, BJ Kim, HJ Cho, CH Park, HJC Choi, EJ Jang, EJ Yang, JA Hwang, SH Woo, JH Lee, JH Park, KM Choi, YY Kwon, CK Lee, JT Park, SC Cho, YI Lee, SB Lee, JA Han, KA Cho, MS Kim, D Hwang, YS Lee, SC Park
    Experimental & Molecular Medicine, 2021;53(6):1092-1108.  2021
  34. Lycorine hydrochloride suppresses stress-induced premature cellular senescence by stabilizing the genome of human cells
    Authors: W Zhang, J Yang, Y Chen, R Xue, Z Mao, W Lu, Y Jiang
    Aging Cell, 2021;0(0):e13307.  2021
  35. Long noncoding RNA BS-DRL1 modulates the DNA damage response and genome stability by interacting with HMGB1 in neurons
    Authors: MM Lou, XQ Tang, GM Wang, J He, F Luo, MF Guan, F Wang, H Zou, JY Wang, Q Zhang, MJ Xu, QL Shi, LB Shen, GM Ma, Y Wu, YY Zhang, AB Liang, TH Wang, LL Xiong, J Wang, J Xu, WY Wang
    Nature Communications, 2021;12(1):4075.  2021
  36. Antifungal agent Terbinafine restrains tumor growth in preclinical models of hepatocellular carcinoma via AMPK-mTOR axis
    Authors: EB Zhang, X Zhang, K Wang, F Zhang, TW Chen, N Ma, QZ Ni, YK Wang, QW Zheng, HJ Cao, J Xia, B Zhu, S Xu, X Ding, X Wang, Z Li, S Cheng, D Xie, JJ Li
    Oncogene, 2021;0(0):.  2021
  37. 13-Acetoxysarcocrassolide Exhibits Cytotoxic Activity Against Oral Cancer Cells Through the Interruption of the Keap1/Nrf2/p62/SQSTM1 Pathway: The Need to Move Beyond Classical Concepts
    Authors: YC Liu, BR Peng, KC Hsu, M El-Shazly, SP Shih, TE Lin, FW Kuo, YC Chou, HY Lin, MC Lu
    Mar Drugs, 2020;18(8):.  2020
  38. Germline biallelic MCM8 variants are associated with early-onset Lynch-like syndrome
    Authors: M Golubicki, L Bonjoch, JG Acuña-Ocho, M Díaz-Gay, J Muñoz, M Cuatrecasa, T Ocaña, S Iseas, G Mendez, D Cisterna, SA Schubert, M Nielsen, T van Wezel, Y Goldberg, E Pikarsky, J Robbio, E Roca, A Castells, F Balaguer, M Antelo, S Castellví-
    JCI Insight, 2020;0(0):.  2020
  39. BRD4 Prevents R-Loop Formation and Transcription-Replication Conflicts by Ensuring Efficient Transcription Elongation
    Authors: DS Edwards, R Maganti, JP Tanksley, J Luo, JJH Park, E Balkanska-, J Ling, SR Floyd
    Cell Rep, 2020;32(12):108166.  2020
  40. Replication Stress Induces Global Chromosome Breakage in the Fragile X Genome
    Authors: A Chakrabort, P Jenjaroenp, J Li, S El Hilali, A McCulley, B Haarer, EA Hoffman, A Belak, A Thorland, H Hehnly, C Schildkrau, CL Chen, VA Kuznetsov, W Feng
    Cell Rep, 2020;32(12):108179.  2020
  41. Inhibition of non-homologous end joining of gamma ray-induced DNA double-strand breaks by cAMP signaling in lung cancer cells
    Authors: SE Noh, YS Juhnn
    Sci Rep, 2020;10(1):14455.  2020
  42. An artificial metalloenzyme for catalytic cancer-specific DNA cleavage and operando imaging
    Authors: L Gao, Y Zhang, L Zhao, W Niu, Y Tang, F Gao, P Cai, Q Yuan, X Wang, H Jiang, X Gao
    Sci Adv, 2020;6(29):eabb1421.  2020
  43. BRD4 prevents the accumulation of R-loops and protects against transcription-replication collision events and DNA damage
    Authors: FC Lam, YW Kong, Q Huang, TL Vu Han, AD Maffa, EM Kasper, MB Yaffe
    Nat Commun, 2020;11(1):4083.  2020
  44. Ligand-induced gene activation is associated with oxidative genome damage whose repair is required for transcription
    Authors: S Sengupta, H Wang, C Yang, B Szczesny, ML Hegde, S Mitra
    Proc. Natl. Acad. Sci. U.S.A., 2020;0(0):.  2020
  45. Signaling from Plastid Genome Stability Modulates Endoreplication and Cell Cycle during Plant Development
    Authors: S Duan, L Hu, B Dong, HL Jin, HB Wang
    Cell Rep, 2020;32(6):108019.  2020
  46. Exome sequencing identifies novel mutation signatures of UV radiation and trichostatin A in primary human keratinocytes
    Authors: Y Shen, W Ha, W Zeng, D Queen, L Liu
    Sci Rep, 2020;10(1):4943.  2020
  47. ATRX/EZH2 complex epigenetically regulates FADD/PARP1 axis, contributing to TMZ resistance in glioma
    Authors: B Han, X Meng, P Wu, Z Li, S Li, Y Zhang, C Zha, Q Ye, C Jiang, J Cai, T Jiang
    Theranostics, 2020;10(7):3351-3365.  2020
  48. Hempseed Lignanamides Rich-Fraction: Chemical Investigation and Cytotoxicity towards U-87 Glioblastoma Cells
    Authors: E Nigro, G Crescente, M Formato, MT Pecoraro, M Mallardo, S Piccolella, A Daniele, S Pacifico
    Molecules, 2020;25(5):.  2020
  49. Extracellular matrix stiffness determines DNA repair efficiency and cellular sensitivity to genotoxic agents
    Authors: M Deng, J Lin, S Nowsheen, T Liu, Y Zhao, PW Villalta, D Sicard, DJ Tschumperl, S Lee, J Kim, Z Lou
    Science Advances, 2020;6(37):.  2020
  50. Fitter Mitochondria Are Associated With Radioresistance in Human Head and Neck SQD9 Cancer Cells
    Authors: D Grasso, HCD Medeiros, LX Zampieri, V Bol, P Danhier, MW van Gisber, C Bouzin, D Brusa, V Grégoire, H Smeets, APM Stassen, LJ Dubois, P Lambin, M Dutreix, P Sonveaux
    Front Pharmacol, 2020;11(0):263.  2020
  51. Deleting key autophagy elongation proteins induces acquirement of tumor-associated phenotypes via ISG15
    Authors: E Kong, HD Kim, J Kim
    Cell Death Differ., 2020;0(0):.  2020
  52. Phosphoglycerate Mutase 1 Activates DNA Damage Repair via Regulation of WIP1 Activity
    Authors: S Ohba, TA Johannesse, K Chatla, X Yang, RO Pieper, J Mukherjee
    Cell Rep, 2020;31(2):107518.  2020
  53. HDAC1 dysregulation induces aberrant cell cycle and DNA damage in progress of TDP-43 proteinopathies
    Authors: CC Wu, LW Jin, IF Wang, WY Wei, PC Ho, YC Liu, KJ Tsai
    EMBO Mol Med, 2020;12(6):e10622.  2020
  54. Cooperation of the NEIL3 and Fanconi anemia/BRCA pathways in interstrand crosslink repair
    Authors: N Li, J Wang, SS Wallace, J Chen, J Zhou, AD D'Andrea
    Nucleic Acids Res., 2020;0(0):.  2020
  55. Autophagy gene haploinsufficiency drives chromosome instability, increases migration, and promotes early ovarian tumors
    Authors: JR Delaney, CB Patel, J Bapat, CM Jones, M Ramos-Zapa, KK Ortell, R Tanios, M Haghighiab, J Axelrod, JW DeStefano, I Tancioni, DD Schlaepfer, O Harismendy, AR La Spada, DG Stupack
    PLoS Genet., 2020;16(1):e1008558.  2020
  56. UBE2O targets Mxi1 for ubiquitination and degradation to promote lung cancer progression and radioresistance
    Authors: Y Huang, X Yang, Y Lu, Y Zhao, R Meng, S Zhang, X Dong, S Xu, G Wu
    Cell Death Differ., 2020;0(0):.  2020
  57. MYC Promotes Bone Marrow Stem Cell Dysfunction in Fanconi Anemia
    Authors: A Rodríguez, K Zhang, A Färkkilä, J Filiatraul, C Yang, M Velázquez, E Furutani, DC Goldman, B García de, G Garza-Mayé, K McQueen, LA Sambel, B Molina, L Torres, M González, E Vadillo, R Pelayo, WH Fleming, M Grompe, A Shimamura, S Hautaniemi, J Greenberge, S Frías, K Parmar, AD D'Andrea
    Cell Stem Cell, 2020;0(0):.  2020
  58. An artificial metalloenzyme for catalytic cancer-specific DNA cleavage and operando imaging
    Authors: L Gao, Y Zhang, L Zhao, W Niu, Y Tang, F Gao, P Cai, Q Yuan, X Wang, H Jiang, X Gao
    Sci Adv, 2020;6(29):eabb1421.  2020
  59. Mahogunin Ring Finger 1 Is Required for Genomic Stability and Modulates the Malignant Phenotype of Melanoma Cells
    Authors: I Martínez-V, M Abrisqueta, C Herraiz, J Sirés-Camp, M Castejón-G, DC Bennett, C Olivares, JC García-Bor, C Jiménez-Ce
    Cancers (Basel), 2020;12(10):.  2020
  60. Phospho-Ser784-VCP Is Required for DNA Damage Response and Is Associated with Poor Prognosis of Chemotherapy-Treated Breast Cancer
    Authors: C Zhu, A Rogers, K Asleh, J Won, D Gao, S Leung, S Li, KR Vij, J Zhu, JM Held, Z You, TO Nielsen, J Shao
    Cell Rep, 2020;31(10):107745.  2020
  61. Inhibition of HIF-1alpha by Atorvastatin During 131I-RTX Therapy in Burkitt's Lymphoma Model
    Authors: EH Kim, HY Ko, AR Yu, H Kim, J Zaheer, HJ Kang, YC Lim, KD Cho, HY Joo, MK Kang, JJ Lee, SS Lee, HJ Kang, SM Lim, JS Kim
    Cancers (Basel), 2020;12(5):.  2020
  62. Antitumor effect of a WEE1 inhibitor and potentiation of olaparib sensitivity by DNA damage response modulation in triple-negative breast cancer
    Authors: DH Ha, A Min, S Kim, H Jang, SH Kim, HJ Kim, HS Ryu, JL Ku, KH Lee, SA Im
    Sci Rep, 2020;10(1):9930.  2020
  63. Persistent DNA damage-induced NLRP12 improves hematopoietic stem cell function
    Authors: Q Lin, L Wu, Z Ma, FA Chowdhury, HH Mazumder, W Du
    JCI Insight, 2020;5(10):.  2020
  64. Antiplasmodial and Genotoxic Study of Selected Ghanaian Medicinal Plants
    Authors: S Adukpo, D Elewosi, RH Asmah, AK Nyarko, PK Ekpe, DA Edoh, MF Ofori
    Evid Based Complement Alternat Med, 2020;2020(0):1582724.  2020
  65. Inhibition of Chk1 by miR-320c increases oxaliplatin responsiveness in triple-negative breast cancer
    Authors: S Lim, Y Kim, SB Lee, HG Kang, DH Kim, JW Park, D Chung, H Kong, KH Yoo, Y Kim, W Han, KH Chun, JH Park
    Oncogenesis, 2020;9(10):91.  2020
  66. Signaling from Plastid Genome Stability Modulates Endoreplication and Cell Cycle during Plant Development
    Authors: S Duan, L Hu, B Dong, HL Jin, HB Wang
    Cell Rep, 2020;32(6):108019.  2020
  67. Ligand-induced gene activation is associated with oxidative genome damage whose repair is required for transcription
    Authors: S Sengupta, H Wang, C Yang, B Szczesny, ML Hegde, S Mitra
    Proc. Natl. Acad. Sci. U.S.A., 2020;0(0):.  2020
  68. BRD4 prevents the accumulation of R-loops and protects against transcription-replication collision events and DNA damage
    Authors: FC Lam, YW Kong, Q Huang, TL Vu Han, AD Maffa, EM Kasper, MB Yaffe
    Nat Commun, 2020;11(1):4083.  2020
  69. Wogonin Induces Apoptosis and Reverses Sunitinib Resistance of Renal Cell Carcinoma Cells via Inhibiting CDK4-RB Pathway
    Authors: Y Wang, S Chen, S Sun, G Liu, L Chen, Y Xia, J Cui, W Wang, X Jiang, L Zhang, Y Zhu, Y Zou, B Shi
    Front Pharmacol, 2020;11(0):1152.  2020
  70. Early neuronal accumulation of DNA double strand breaks in Alzheimer's disease
    Authors: NM Shanbhag, MD Evans, W Mao, AL Nana, WW Seeley, A Adame, RA Rissman, E Masliah, L Mucke
    Acta Neuropathol Commun, 2019;7(1):77.  2019
  71. Lineage Tracing Reveals a Subset of Reserve Muscle Stem Cells Capable of Clonal Expansion under Stress
    Authors: A Scaramozza, D Park, S Kollu, I Beerman, X Sun, DJ Rossi, CP Lin, DT Scadden, C Crist, AS Brack
    Cell Stem Cell, 2019;0(0):.  2019
  72. Canonical cytosolic iron-sulfur cluster assembly and non-canonical functions of DRE2 in Arabidopsis
    Authors: X Wang, X Chen, L Sun, W Qian
    PLoS Genet., 2019;15(4):e1008094.  2019
  73. The Antioxidant from Ethanolic Extract of Rosa cymosa Fruits Activates Phosphatase and Tensin Homolog In Vitro and In Vivo: A New Insight on Its Antileukemic Effect
    Authors: KC Wang, YC Liu, M El-Shazly, SP Shih, YC Du, YM Hsu, HY Lin, YC Chen, YC Wu, SC Yang, MC Lu
    Int J Mol Sci, 2019;20(8):.  2019
  74. MiR-34s negatively regulate homologous recombination through targeting RAD51
    Authors: S Chen, R Liu, Q Wang, Z Qi, Y Hu, P Zhou, Z Wang
    Arch. Biochem. Biophys., 2019;666(0):73-82.  2019
  75. Berberine downregulates CDC6 and inhibits proliferation via targeting JAK-STAT3 signaling in keratinocytes
    Authors: S Sun, X Zhang, M Xu, F Zhang, F Tian, J Cui, Y Xia, C Liang, S Zhou, H Wei, H Zhao, G Wu, B Xu, X Liu, G Yang, Q Wang, L Zhang, Y Gong, C Shao, Y Zou
    Cell Death Dis, 2019;10(4):274.  2019
  76. PPAR? Interaction with UBR5/ATMIN Promotes DNA Repair to Maintain Endothelial Homeostasis
    Authors: CG Li, C Mahon, NM Sweeney, E Verschuere, V Kantamani, D Li, JK Hennigs, DP Marciano, I Diebold, O Abu-Halawa, M Elliott, S Sa, F Guo, L Wang, A Cao, C Guignabert, J Sollier, NP Nickel, M Kaschwich, KA Cimprich, M Rabinovitc
    Cell Rep, 2019;26(5):1333-1343.e7.  2019
  77. Myeloid cell-derived HB-EGF Drives Tissue Recovery After Pancreatitis
    Authors: HJ Wen, S Gao, Y Wang, M Ray, MA Magnuson, CVE Wright, MP Di Maglian, TL Frankel, HC Crawford
    Cell Mol Gastroenterol Hepatol, 2019;0(0):.  2019
  78. Early-onset aging and mitochondrial defects associated with loss of histone acetyltransferase 1 (Hat1)
    Authors: P Nagarajan, PA Agudelo Ga, CC Iyer, LV Popova, WD Arnold, MR Parthun
    Aging Cell, 2019;0(0):e12992.  2019
  79. miR-200c Modulates the Pathogenesis of Radiation-Induced Oral Mucositis
    Authors: J Tao, M Fan, D Zhou, Y Hong, J Zhang, H Liu, S Sharma, G Wang, Q Dong
    Oxid Med Cell Longev, 2019;2019(0):2352079.  2019
  80. A SWI/SNF subunit regulates chromosomal dissociation of structural maintenance complex 5 during DNA repair in plant cells
    Authors: J Jiang, N Mao, H Hu, J Tang, D Han, S Liu, Q Wu, Y Liu, C Peng, J Lai, C Yang
    Proc. Natl. Acad. Sci. U.S.A., 2019;0(0):.  2019
  81. OTU deubiquitinase 4 is silenced and radiosensitizes non-small cell lung cancer cells via inhibiting DNA repair
    Authors: Z Wu, M Qiu, Y Guo, J Zhao, Z Liu, H Wang, M Meng, Z Yuan, Z Mi
    Cancer Cell Int., 2019;19(0):99.  2019
  82. Protective effects of novel derivatives of vitamin D3 and lumisterol against UVB-induced damage in human keratinocytes involve activation of Nrf2 and p53 defense mechanisms
    Authors: A Chaiprason, Z Janjetovic, TK Kim, SG Jarrett, JA D'Orazio, MF Holick, EKY Tang, RC Tuckey, U Panich, W Li, AT Slominski
    Redox Biol, 2019;24(0):101206.  2019
  83. PP2AC? deficiency impairs early cortical development through inducing DNA damage in neuroprojenitor cells
    Authors: B Liu, L Lin, S Riazuddin, A Zubair, L Wang, LJ Di, R Li, TT Dong, CX Deng, WM Tong
    Int. J. Biochem. Cell Biol., 2019;109(0):40-58.  2019
  84. Delta-24-RGD combined with radiotherapy exerts a potent antitumor effect in diffuse intrinsic pontine glioma and pediatric high grade glioma models
    Authors: N Martinez-V, M Marigil, M García-Mou, M Gonzalez-H, JJ Aristu, LI Ramos-Garc, S Tejada, R Díez-Valle, A Patiño-Gar, OJ Becher, C Gomez-Manz, J Fueyo, MM Alonso
    Acta Neuropathol Commun, 2019;7(1):64.  2019
  85. Nitric oxide-donor/PARP-inhibitor combination: A new approach for sensitization to ionizing radiation
    Authors: A Wilson, V Menon, Z Khan, A Alam, L Litovchick, V Yakovlev
    Redox Biol, 2019;24(0):101169.  2019
  86. Trabectedin triggers direct and NK-mediated cytotoxicity in multiple myeloma
    Authors: M Cucè, ME Gallo Cant, MA Siciliano, C Riillo, D Caracciolo, F Scionti, N Staropoli, V Zuccalà, L Maltese, A Di Vito, K Grillone, V Barbieri, M Arbitrio, MT Di Martino, M Rossi, N Amodio, P Tagliaferr, P Tassone, C Botta
    J Hematol Oncol, 2019;12(1):32.  2019
  87. Molecular damage and responses of oral keratinocyte to hydrogen peroxide
    Authors: KY Lin, CH Chung, JS Ciou, PF Su, PW Wang, DB Shieh, TC Wang
    BMC Oral Health, 2019;19(1):10.  2019
  88. ITPase deficiency causes a Martsolf-like syndrome with a lethal infantile dilated cardiomyopathy
    Authors: MT Handley, K Reddy, J Wills, E Rosser, A Kamath, M Halachev, G Falkous, D Williams, P Cox, A Meynert, ES Raymond, H Morrison, S Brown, E Allan, I Aligianis, AP Jackson, BH Ramsahoye, A von Kriegs, RW Taylor, AJ Finch, DR FitzPatric
    PLoS Genet., 2019;15(3):e1007605.  2019
  89. Promotion of homology-directed DNA repair by polyamines
    Authors: CY Lee, GC Su, WY Huang, MY Ko, HY Yeh, GD Chang, SJ Lin, P Chi
    Nat Commun, 2019;10(1):65.  2019
  90. Preclinical study using androgen receptor (AR) degradation enhancer to increase radiotherapy efficacy via targeting radiation-increased AR to better suppress prostate cancer progression
    Authors: FJ Chou, Y Chen, D Chen, Y Niu, G Li, P Keng, S Yeh, C Chang
    EBioMedicine, 2019;0(0):.  2019
  91. Molecular origin of AuNPs-induced cytotoxicity and mechanistic study
    Authors: E Lee, H Jeon, M Lee, J Ryu, C Kang, S Kim, J Jung, Y Kwon
    Sci Rep, 2019;9(1):2494.  2019
  92. Nucleostemin reveals a dichotomous nature of genome maintenance in mammary tumor progression
    Authors: T Lin, TC Lin, DJ McGrail, PK Bhupal, YH Ku, W Zhang, L Meng, SY Lin, G Peng, RYL Tsai
    Oncogene, 2019;0(0):.  2019
  93. Absence of Cytosolic 2-Cys Prx Subtypes I and II Exacerbates TNF-?-Induced Apoptosis via Different Routes
    Authors: S Lee, JY Lee, EW Lee, S Park, DH Kang, C Min, DJ Lee, D Kang, J Song, J Kwon, SW Kang
    Cell Rep, 2019;26(8):2194-2211.e6.  2019
  94. Epithelial?mesenchymal transition induced by bone morphogenetic protein 9 hinders cisplatin efficacy in ovarian cancer cells
    Authors: Y Wang, B Yang, J Zhao, X Yu, X Liu, L Zhang, Y Zhang, X Li, Z Zhai
    Mol Med Rep, 2019;0(0):.  2019
  95. Male mice, caged in the International Space Station for 35 days, sire healthy offspring
    Authors: T Matsumura, T Noda, M Muratani, R Okada, M Yamane, A Isotani, T Kudo, S Takahashi, M Ikawa
    Sci Rep, 2019;9(1):13733.  2019
  96. PAGE4 promotes prostate cancer cells survive under oxidative stress through modulating MAPK/JNK/ERK pathway
    Authors: C Lv, S Fu, Q Dong, Z Yu, G Zhang, C Kong, C Fu, Y Zeng
    J. Exp. Clin. Cancer Res., 2019;38(1):24.  2019
  97. DNA damage-induced PARP1 activation confers cardiomyocyte dysfunction through NAD+ depletion in experimental atrial fibrillation
    Authors: D Zhang, X Hu, J Li, J Liu, L Baks-Te Bu, M Wiersma, NU Malik, DMS van Marion, M Tolouee, F Hoogstra-B, EAH Lanters, AM van Roon, AAF de Vries, DA Pijnappels, NMS de Groot, RH Henning, BJJM Brundel
    Nat Commun, 2019;10(1):1307.  2019
  98. Prolyl isomerization of FAAP20 catalyzed by PIN1 regulates the Fanconi anemia pathway
    Authors: J Wang, B Chan, M Tong, Y Paung, U Jo, D Martin, M Seeliger, J Haley, H Kim
    PLoS Genet., 2019;15(2):e1007983.  2019
  99. MiR-210-3p protects endometriotic cells from oxidative stress-induced cell cycle arrest by targeting BARD1
    Authors: Y Dai, X Lin, W Xu, X Lin, Q Huang, L Shi, Y Pan, Y Zhang, Y Zhu, C Li, L Liu, S Zhang
    Cell Death Dis, 2019;10(2):144.  2019
  100. Water soluble and insoluble components of PM2.5 and their functional cardiotoxicities on neonatal rat cardiomyocytes in vitro
    Authors: Z Qi, Y Song, Q Ding, X Liao, R Li, G Liu, S Tsang, Z Cai
    Ecotoxicol. Environ. Saf., 2019;168(0):378-387.  2019
  101. ATM orchestrates the DNA-damage response to counter toxic non-homologous end-joining at broken replication forks
    Authors: G Balmus, D Pilger, J Coates, M Demir, M Sczaniecka, AC Barros, M Woods, B Fu, F Yang, E Chen, M Ostermaier, T Stankovic, H Ponstingl, M Herzog, K Yusa, FM Martinez, ST Durant, Y Galanty, P Beli, DJ Adams, A Bradley, E Metzakopia, JV Forment, SP Jackson
    Nat Commun, 2019;10(1):87.  2019
  102. miR-205 enhances radiation sensitivity of prostate cancer cells by impairing DNA damage repair through PKC? and ZEB1 inhibition
    Authors: R El Bezawy, S Tinelli, M Tortoreto, V Doldi, V Zuco, M Folini, C Stucchi, T Rancati, R Valdagni, P Gandellini, N Zaffaroni
    J. Exp. Clin. Cancer Res., 2019;38(1):51.  2019
  103. A PLK1 kinase inhibitor enhances the chemosensitivity of cisplatin by inducing pyroptosis in oesophageal squamous cell carcinoma
    Authors: M Wu, Y Wang, D Yang, Y Gong, F Rao, R Liu, Y Danna, J Li, J Fan, J Chen, W Zhang, Q Zhan
    EBioMedicine, 2019;0(0):.  2019
  104. Neuroprotective effects of blueberry anthocyanins against perfluorooctanoic sulfonate on planarian Dugesia japonica
    Authors: X Shao, B Zhao, B Wang, B Zhao, Y Zhu, Z Yuan, J Zhang
    Ecotoxicol. Environ. Saf., 2019;175(0):39-47.  2019
  105. Synthetic lethality between BRCA1 deficiency and poly(ADP-ribose) polymerase inhibition is modulated by processing of endogenous oxidative DNA damage
    Authors: S Giovannini, MC Weller, S Repmann, H Moch, J Jiricny
    Nucleic Acids Res., 2019;0(0):.  2019
  106. Rap1 regulates hematopoietic stem cell survival and affects oncogenesis and response to chemotherapy
    Authors: E Khattar, KZY Maung, CL Chew, A Ghosh, MMH Mok, P Lee, J Zhang, WHJ Chor, G Cildir, CQ Wang, NK Mohd-Ismai, DWL Chin, SC Lee, H Yang, YJ Shin, DH Nam, L Chen, AP Kumar, LW Deng, M Ikawa, J Gunaratne, M Osato, V Tergaonkar
    Nat Commun, 2019;10(1):5349.  2019
  107. LOXL2-mediated H3K4 oxidation reduces chromatin accessibility in triple-negative breast cancer cells
    Authors: JP Cebrià-Cos, L Pascual-Re, A Gonzalez-P, G Serra-Bard, J Querol, M Cosín, G Verde, RA Cigliano, W Sanseverin, S Segura-Bay, A Iturbide, D Andreu, P Nuciforo, C Bernado-Mo, V Rodilla, J Arribas, J Yelamos, AG de Herrero, TH Stracker, S Peiró
    Oncogene, 2019;0(0):.  2019
  108. Acquired Resistance of EGFR-Mutated Lung Cancer to Tyrosine Kinase Inhibitor Treatment Promotes PARP Inhibitor Sensitivity
    Authors: L Marcar, K Bardhan, L Gheorghiu, P Dinkelborg, H Pfäffle, Q Liu, M Wang, Z Piotrowska, LV Sequist, K Borgmann, JE Settleman, JA Engelman, AN Hata, H Willers
    Cell Rep, 2019;27(12):3422-3432.e4.  2019
  109. ATAD5 promotes replication restart by regulating RAD51 and PCNA in response to replication stress
    Authors: SH Park, N Kang, E Song, M Wie, EA Lee, S Hwang, D Lee, JS Ra, IB Park, J Park, S Kang, JH Park, S Hohng, KY Lee, K Myung
    Nat Commun, 2019;10(1):5718.  2019
  110. IL-24 Inhibits Lung Cancer Growth by Suppressing GLI1 and Inducing DNA Damage
    Authors: J Panneersel, A Srivastava, M Mehta, A Chen, YD Zhao, A Munshi, R Ramesh
    Cancers (Basel), 2019;11(12):.  2019
  111. Prexasertib treatment induces homologous recombination deficiency and synergizes with olaparib in triple-negative breast cancer cells
    Authors: C Mani, S Jonnalagad, J Lingareddy, S Awasthi, WH Gmeiner, K Palle
    Breast Cancer Res., 2019;21(1):104.  2019
  112. Combined Targeting of G9a and Checkpoint kinase 1 Synergistically Inhibits Pancreatic Cancer Cell Growth by Replication Fork Collapse
    Authors: G Urrutia, A Salmonson, JA Toro-Zapat, TM de Assunca, A Mathison, N Dusetti, J Iovanna, R Urrutia, G Lomberk
    Mol. Cancer Res., 2019;0(0):.  2019
  113. HuR Reduces Radiation-Induced DNA Damage by Enhancing Expression of ARID1A
    Authors: D Andrade, M Mehta, J Griffith, S Oh, J Corbin, A Babu, S De, A Chen, YD Zhao, S Husain, S Roy, L Xu, J Aube, R Janknecht, M Gorospe, T Herman, R Ramesh, A Munshi
    Cancers (Basel), 2019;11(12):.  2019
  114. Combined cell death of co-exposure to aldehyde mixtures on human bronchial epithelial BEAS-2B cells: Molecular insights into the joint action
    Authors: S Zhang, J Zhang, W Cheng, H Chen, A Wang, Y Liu, H Hou, Q Hu
    Chemosphere, 2019;244(0):125482.  2019
  115. Selective Killing of RAS-Malignant Tissues by Exploiting Oncogene-Induced DNA Damage
    Authors: L Murcia, M Clemente-R, P Pierre-Eli, A Royou, M Milán
    Cell Rep, 2019;28(1):119-131.e4.  2019
  116. Pwp1 regulates telomere length by stabilizing shelterin complex and maintaining histone H4K20 trimethylation
    Authors: Y Yu, W Jia, Y Lyu, D Su, M Bai, J Shen, J Qiao, T Han, W Liu, J Chen, W Chen, D Ye, X Guo, S Zhu, J Xi, R Zhu, X Wan, S Gao, J Zhu, J Kang
    Cell Discov, 2019;5(0):47.  2019
  117. Mortaparib, a novel dual inhibitor of mortalin and PARP1, is a potential drug candidate for ovarian and cervical cancers
    Authors: JF Putri, P Bhargava, JK Dhanjal, T Yaguchi, D Sundar, SC Kaul, R Wadhwa
    J. Exp. Clin. Cancer Res., 2019;38(1):499.  2019
  118. Deletion of the SAPS1 subunit of protein phosphatase 6 in mice increases radiosensitivity and impairs the cellular DNA damage response
    Authors: J Dziegielew, MA Bo?kowska, EA Poniecka, J Heo, K Du, RB Crittenden, TP Bender, DL Brautigan, JM Larner
    DNA Repair (Amst.), 2019;85(0):102737.  2019
  119. Anticancer effect of fucoidan on cell proliferation, cell cycle progression, genetic damage and apoptotic cell death in HepG2 cancer cells
    Authors: A P, A K, S L, M M, M K
    Toxicol Rep, 2019;6(0):556-563.  2019
  120. MRE11-RAD50-NBS1 promotes Fanconi Anemia R-loop suppression at transcription-replication conflicts
    Authors: EY Chang, S Tsai, MJ Aristizaba, JP Wells, Y Coulombe, FF Busatto, YA Chan, A Kumar, Y Dan Zhu, AY Wang, LA Fournier, P Hieter, MS Kobor, JY Masson, PC Stirling
    Nat Commun, 2019;10(1):4265.  2019
  121. APC loss affects DNA damage repair causing doxorubicin resistance in breast cancer cells
    Authors: CD Stefanski, K Keffler, S McClintock, L Milac, JR Prosperi
    Neoplasia, 2019;21(12):1143-1150.  2019
  122. Celastrol-induced degradation of FANCD2 sensitizes pediatric high-grade gliomas to the DNA-crosslinking agent carboplatin
    Authors: DS Metselaar, MH Meel, B Benedict, P Waranecki, J Koster, GJL Kaspers, E Hulleman
    EBioMedicine, 2019;0(0):.  2019
  123. Exploring the kidney hazard of exposure to mercuric chloride in mice:Disorder of mitochondrial dynamics induces oxidative stress and results in apoptosis
    Authors: S Li, R Baiyun, Z Lv, J Li, D Han, W Zhao, L Yu, N Deng, Z Liu, Z Zhang
    Chemosphere, 2019;234(0):822-829.  2019
  124. Cisplatin exposure causes c-Myc-dependent resistance to CDK4/6 inhibition in HPV-negative head and neck squamous cell carcinoma
    Authors: AM Robinson, R Rathore, NJ Redlich, DR Adkins, T VanArsdale, BA Van Tine, LS Michel
    Cell Death Dis, 2019;10(11):867.  2019
  125. Acetylshikonin Sensitizes Hepatocellular Carcinoma Cells to Apoptosis through ROS-Mediated Caspase Activation
    Authors: M Hong, J Li, S Li, M M Almutair
    Cells, 2019;8(11):.  2019
  126. BIRC5/Survivin is a novel ATG12-ATG5 conjugate interactor and an autophagy-induced DNA damage suppressor in human cancer and mouse embryonic fibroblast cells
    Authors: TY Lin, HH Chan, SH Chen, S Sarvagalla, PS Chen, MS Coumar, SM Cheng, YC Chang, CH Lin, E Leung, CHA Cheung
    Autophagy, 2019;0(0):1-18.  2019
  127. Luminescent ruthenium(II) polypyridyl complexes acted as radiosensitizer for pancreatic cancer by enhancing radiation-induced DNA damage
    Authors: Y Zhou, Y Xu, L Lu, J Ni, J Nie, J Cao, Y Jiao, Q Zhang
    Theranostics, 2019;9(22):6665-6675.  2019
  128. Precision Chemo-Radiotherapy for HER2 Tumors Using Antibody Conjugates of an Auristatin Derivative with Reduced Cell Permeability
    Authors: DV Hingorani, MK Doan, MF Camargo, J Aguilera, SM Song, D Pizzo, DJ Scanderbeg, EEW Cohen, AM Lowy, SR Adams, SJ Advani
    Mol. Cancer Ther., 2019;0(0):.  2019
  129. Transcriptional Modulation by Idelalisib Synergizes with Bendamustine in Chronic Lymphocytic Leukemia
    Authors: SEF Kost, A Saleh, EM Mejia, M Mostafizar, EDJ Bouchard, V Banerji, AJ Marshall, SB Gibson, JB Johnston, S Katyal
    Cancers (Basel), 2019;11(10):.  2019
  130. The miR-205-5p/BRCA1/RAD17 Axis Promotes Genomic Instability in Head and Neck Squamous Cell Carcinomas
    Authors: F Valenti, A Sacconi, F Ganci, G Grasso, S Strano, G Blandino, S Di Agostin
    Cancers (Basel), 2019;11(9):.  2019
  131. TRIM66 reads unmodified H3R2K4 and H3K56ac to respond to DNA damage in embryonic stem cells
    Authors: J Chen, Z Wang, X Guo, F Li, Q Wei, X Chen, D Gong, Y Xu, W Chen, Y Liu, J Kang, Y Shi
    Nat Commun, 2019;10(1):4273.  2019
  132. Dual Processing of R-Loops and Topoisomerase I Induces Transcription-Dependent DNA Double-Strand Breaks
    Authors: A Cristini, G Ricci, S Britton, S Salimbeni, SN Huang, J Marinello, P Calsou, Y Pommier, G Favre, G Capranico, N Gromak, O Sordet
    Cell Rep, 2019;28(12):3167-3181.e6.  2019
  133. Protein phosphatase 2A controls ongoing DNA replication by binding to and regulating cell division cycle 45 (CDC45)
    Authors: AL Perl, CM O'Connor, P Fa, F Mayca Pozo, J Zhang, Y Zhang, G Narla
    J. Biol. Chem., 2019;0(0):.  2019
  134. Intrinsic adriamycin resistance in p53-mutated breast cancer is related to the miR-30c/FANCF/REV1-mediated DNA damage response
    Authors: S Lin, L Yu, X Song, J Bi, L Jiang, Y Wang, M He, Q Xiao, M Sun, OI Olopade, L Zhao, M Wei
    Cell Death Dis, 2019;10(9):666.  2019
  135. Keap1 controls protein S-nitrosation and apoptosis-senescence switch in endothelial cells
    Authors: A Kopacz, D Klóska, B Proniewski, D Cysewski, N Personnic, A Piechota-P, P Kaczara, A Zakrzewska, HJ Forman, J Dulak, A Józkowicz, A Grochot-Pr
    Redox Biol, 2019;28(0):101304.  2019
  136. E-cigarette flavored pods induce inflammation, epithelial barrier dysfunction, and DNA damage in lung epithelial cells and monocytes
    Authors: T Muthumalag, T Lamb, MR Friedman, I Rahman
    Sci Rep, 2019;9(1):19035.  2019
  137. Kinase-dead ATR differs from ATR loss by limiting the dynamic exchange of ATR and RPA
    Authors: D Menolfi, W Jiang, BJ Lee, T Moiseeva, Z Shao, V Estes, MG Frattini, CJ Bakkenist, S Zha
    Nat Commun, 2018;9(1):5351.  2018
  138. DNA-PK inhibition synergizes with oncolytic virus M1 by inhibiting antiviral response and potentiating DNA damage
    Authors: X Xiao, J Liang, C Huang, K Li, F Xing, W Zhu, Z Lin, W Xu, G Wu, J Zhang, X Lin, Y Tan, J Cai, J Hu, X Chen, Y Huang, Z Qin, P Qiu, X Su, L Chen, Y Lin, H Zhang, G Yan
    Nat Commun, 2018;9(1):4342.  2018
  139. Macrophages Regulate the Systemic Response to DNA Damage by a Cell Nonautonomous Mechanism.
    Authors: Geiger-Maor A, Guedj A, Even-Ram S, Smith Y, Galun E, Rachmilewitz J
    Cancer Res, 2015;75(13):2663-73.  2015
  140. Targeting HGF/c-MET induces cell cycle arrest, DNA damage, and apoptosis for primary effusion lymphoma.
    Authors: Dai L, Trillo-Tinoco J, Cao Y, Bonstaff K, Doyle L, Del Valle L, Whitby D, Parsons C, Reiss K, Zabaleta J, Qin Z
    Blood, 2015;126(26):2821-31.  2015
  141. Improved apoptotic cell death in drug-resistant non-small-cell lung cancer cells by tumor necrosis factor-related apoptosis-inducing ligand-based treatment.
    Authors: Gatti L, Cossa G, Tinelli S, Carenini N, Arrighetti N, Pennati M, Cominetti D, de Cesare M, Zunino F, Zaffaroni N, Perego P
    J Pharmacol Exp Ther, 2014;348(3):360-71.  2014
  142. CRL4Cdt2 E3 ubiquitin ligase and proliferating cell nuclear antigen (PCNA) cooperate to degrade thymine DNA glycosylase in S phase.
    Authors: Shibata E, Dar A, Dutta A
    J Biol Chem, 2014;289(33):23056-64.  2014
  143. Tripartite Motif-containing 33 (TRIM33) protein functions in the poly(ADP-ribose) polymerase (PARP)-dependent DNA damage response through interaction with Amplified in Liver Cancer 1 (ALC1) protein.
    Authors: Kulkarni A, Oza J, Yao M, Sohail H, Ginjala V, Tomas-Loba A, Horejsi Z, Tan A, Boulton S, Ganesan S
    J Biol Chem, 2013;288(45):32357-69.  2013
  144. DNA damage in normally and prematurely aged mice.
    Authors: Maslov A, Ganapathi S, Westerhof M, Quispe-Tintaya W, White R, Van Houten B, Reiling E, Dolle M, van Steeg H, Hasty P, Hoeijmakers J, Vijg J
    Aging Cell, 2013;12(3):467-77.  2013
  145. Low and high linear energy transfer radiation sensitization of HCC cells by metformin.
    Authors: Kim E, Kim M, Cho C, Jung W, Jeong Y, Jeong J
    J Radiat Res, 2013;55(3):432-42.  2013
  146. Dbf4 is direct downstream target of ataxia telangiectasia mutated (ATM) and ataxia telangiectasia and Rad3-related (ATR) protein to regulate intra-S-phase checkpoint.
    Authors: Lee AY, Chiba T, Truong LN
    J. Biol. Chem., 2012;287(4):2531-43.  2012
  147. BID Binds to Replication Protein A and Stimulates ATR Function following Replicative Stress.
    Authors: Liu Y, Vaithiyalingam S, Shi Q
    Mol. Cell. Biol., 2011;31(21):4298-309.  2011
  148. Multiple DNA damage signaling and repair pathways deregulated by simian virus 40 large T antigen.
    Authors: Boichuk S, Hu L, Hein J
    J. Virol., 2010;84(16):8007-20.  2010
  149. The microtubule-targeting agent CA4P regresses leukemic xenografts by disrupting interaction with vascular cells and mitochondrial-dependent cell death.
    Authors: Petit I, Karajannis MA, Vincent L, Young L, Butler J, Hooper AT, Shido K, Steller H, Chaplin DJ, Feldman E, Rafii S
    Blood, 2007;111(4):1951-61.  2007
  150. Human liver sinusoidal endothelial cells induce apoptosis in activated T cells: a role in tolerance induction.
    Authors: Karrar A, Broome U, Uzunel M, Qureshi AR, Sumitran-Holgersson S
    Gut, 2006;56(2):243-52.  2006
  151. The hypoxia-inducible factor renders cancer cells more sensitive to vitamin C-induced toxicity.
    Authors: Tian W, Wang Y, Xu Y, Guo X, Wang B, Sun L, Liu L, Cui F, Zhuang Q, Bao X, Schley G, Chung T, Laslett A, Willam C, Qin B, Maxwell P, Esteban M
    J Biol Chem, 0;289(6):3339-51.  0
  152. Potential for genomic instability associated with retrotranspositionally-incompetent L1 loci.
    Authors: Kines K, Sokolowski M, deHaro D, Christian C, Belancio V
    Nucleic Acids Res, 0;42(16):10488-502.  0
  153. Self assembled dual responsive micelles stabilized with protein for co-delivery of drug and siRNA in cancer therapy.
    Authors: Aji Alex M, Nehate C, Veeranarayanan S, Kumar D, Kulshreshtha R, Koul V
    Biomaterials, 0;133(0):94-106.  0
  154. USP28 is recruited to sites of DNA damage by the tandem BRCT domains of 53BP1 but plays a minor role in double-strand break metabolism.
    Authors: Knobel P, Belotserkovskaya R, Galanty Y, Schmidt C, Jackson S, Stracker T
    Mol Cell Biol, 0;34(11):2062-74.  0
  155. 53BP1 promotes microhomology-mediated end-joining in G1-phase cells.
    Authors: Xiong X, Du Z, Wang Y, Feng Z, Fan P, Yan C, Willers H, Zhang J
    Nucleic Acids Res, 0;43(3):1659-70.  0
  156. RhoB promotes gammaH2AX dephosphorylation and DNA double-strand break repair.
    Authors: Mamouni K, Cristini A, Guirouilh-Barbat J, Monferran S, Lemarie A, Faye J, Lopez B, Favre G, Sordet O
    Mol Cell Biol, 0;34(16):3144-55.  0
  157. Targeting aberrant DNA double-strand break repair in triple-negative breast cancer with alpha-particle emitter radiolabeled anti-EGFR antibody.
    Authors: Song H, Hedayati M, Hobbs R, Shao C, Bruchertseifer F, Morgenstern A, Deweese T, Sgouros G
    Mol Cancer Ther, 0;12(10):2043-54.  0
  158. Damage response of XRCC1 at sites of DNA single strand breaks is regulated by phosphorylation and ubiquitylation after degradation of poly(ADP-ribose).
    Authors: Wei L, Nakajima S, Hsieh C, Kanno S, Masutani M, Levine A, Yasui A, Lan L
    J Cell Sci, 0;126(0):4414-23.  0
  159. Lurbinectedin Specifically Triggers the Degradation of Phosphorylated RNA Polymerase II and the Formation of DNA Breaks in Cancer Cells.
    Authors: Santamaria Nunez G, Robles C, Giraudon C, Martinez-Leal J, Compe E, Coin F, Aviles P, Galmarini C, Egly J
    Mol Cancer Ther, 0;15(10):2399-2412.  0
  160. A novel role for the Pol I transcription factor UBTF in maintaining genome stability through the regulation of highly transcribed Pol II genes.
    Authors: Sanij E, Diesch J, Lesmana A, Poortinga G, Hein N, Lidgerwood G, Cameron D, Ellul J, Goodall G, Wong L, Dhillon A, Hamdane N, Rothblum L, Pearson R, Haviv I, Moss T, Hannan R
    Genome Res, 0;25(2):201-12.  0
  161. Long noncoding RNA POU6F2-AS2 is associated with oesophageal squamous cell carcinoma.
    Authors: Liu J, Sun X, Zhu H, Qin Q, Yang X, Sun X
    J Biochem, 0;160(4):195-204.  0
  162. The NEK1 interactor, C21ORF2, is required for efficient DNA damage repair.
    Authors: Fang X, Lin H, Wang X, Zuo Q, Qin J, Zhang P
    Acta Biochim Biophys Sin (Shanghai), 0;47(10):834-41.  0
  163. Dynamic regulation of Rad51 by E2F1 and p53 in prostate cancer cells upon drug-induced DNA damage under hypoxia.
    Authors: Wu M, Wang X, McGregor N, Pienta K, Zhang J
    Mol Pharmacol, 0;85(6):866-76.  0
  164. Co-targeting of convergent nucleotide biosynthetic pathways for leukemia eradication.
    Authors: Nathanson D, Armijo A, Tom M, Li Z, Dimitrova E, Austin W, Nomme J, Campbell D, Ta L, Le T, Lee J, Darvish R, Gordin A, Wei L, Liao H, Wilks M, Martin C, Sadeghi S, Murphy J, Boulos N, Phelps M, Faull K, Herschman H, Jung M, Czernin J, Lavie A, Radu C
    J Exp Med, 0;211(3):473-86.  0
  165. YU238259 Is a Novel Inhibitor of Homology-Dependent DNA Repair That Exhibits Synthetic Lethality and Radiosensitization in Repair-Deficient Tumors.
    Authors: Stachelek G, Peterson-Roth E, Liu Y, Fernandez R, Pike L, Qian J, Abriola L, Hoyer D, Hungerford W, Merkel J, Glazer P
    Mol Cancer Res, 0;13(10):1389-97.  0
  166. Distribution, quantification and toxicity of cinnamaldehyde in electronic cigarette refill fluids and aerosols.
    Authors: Behar R, Luo W, Lin S, Wang Y, Valle J, Pankow J, Talbot P
    Tob Control, 0;25(0):ii94-ii102.  0
  167. BRUCE regulates DNA double-strand break response by promoting USP8 deubiquitination of BRIT1.
    Authors: Ge C, Che L, Ren J, Pandita R, Lu J, Li K, Pandita T, Du C
    Proc Natl Acad Sci U S A, 0;112(11):E1210-9.  0
  168. Dual functions of the homeoprotein DLX4 in modulating responsiveness of tumor cells to topoisomerase II-targeting drugs.
    Authors: Trinh B, Ko S, Barengo N, Lin S, Naora H
    Cancer Res, 0;73(2):1000-10.  0
  169. Homologous recombination repair signaling in chemical carcinogenesis: prolonged particulate hexavalent chromium exposure suppresses the Rad51 response in human lung cells.
    Authors: Qin Q, Xie H, Wise S, Browning C, Thompson K, Holmes A, Wise J
    Toxicol Sci, 0;142(1):117-25.  0
  170. Connexin 30 expression inhibits growth of human malignant gliomas but protects them against radiation therapy.
    Authors: Artesi M, Kroonen J, Bredel M, Nguyen-Khac M, Deprez M, Schoysman L, Poulet C, Chakravarti A, Kim H, Scholtens D, Seute T, Rogister B, Bours V, Robe P
    Neuro Oncol, 0;17(3):392-406.  0
  171. Ghrelin Prevents Cisplatin-Induced Testicular Damage by Facilitating Repair of DNA Double Strand Breaks Through Activation of p53 in Mice.
    Authors: Garcia J, Chen J, Guillory B, Donehower L, Smith R, Lamb D
    Biol Reprod, 0;93(1):24.  0
  172. Identification and characterization of a potent activator of p53-independent cellular senescence via a small-molecule screen for modifiers of the integrated stress response.
    Authors: Sayers C, Papandreou I, Guttmann D, Maas N, Diehl J, Witze E, Koong A, Koumenis C
    Mol Pharmacol, 0;83(3):594-604.  0
  173. Special AT-rich Sequence-binding Protein 1 (SATB1) Functions as an Accessory Factor in Base Excision Repair.
    Authors: Kaur S, Coulombe Y, Ramdzan Z, Leduy L, Masson J, Nepveu A
    J Biol Chem, 0;291(43):22769-22780.  0
  174. HTLV-1 bZIP factor HBZ promotes cell proliferation and genetic instability by activating OncomiRs.
    Authors: Vernin C, Thenoz M, Pinatel C, Gessain A, Gout O, Delfau-Larue M, Nazaret N, Legras-Lachuer C, Wattel E, Mortreux F
    Cancer Res, 0;74(21):6082-93.  0
  175. Damaging legacy: maternal cigarette smoking has long-term consequences for male offspring fertility.
    Authors: Sobinoff A, Sutherland J, Beckett E, Stanger S, Johnson R, Jarnicki A, McCluskey A, St John J, Hansbro P, McLaughlin E
    Hum Reprod, 0;29(12):2719-35.  0
  176. A novel role of Kruppel-like factor 8 in DNA repair in breast cancer cells.
    Authors: Lu H, Hu L, Li T, Lahiri S, Shen C, Wason M, Mukherjee D, Xie H, Yu L, Zhao J
    J Biol Chem, 0;287(52):43720-9.  0
  177. DNA double-strand break repair: a theoretical framework and its application.
    Authors: Murray P, Cornelissen B, Vallis K, Chapman S
    J R Soc Interface, 0;13(114):20150679.  0
  178. Human CDK18 promotes replication stress signaling and genome stability.
    Authors: Barone G, Staples C, Ganesh A, Patterson K, Bryne D, Myers K, Patil A, Eyers C, Maslen S, Skehel J, Eyers P, Collis S
    Nucleic Acids Res, 0;44(18):8772-8785.  0
  179. EGFR-activating mutations correlate with a Fanconi anemia-like cellular phenotype that includes PARP inhibitor sensitivity.
    Authors: Pfaffle H, Wang M, Gheorghiu L, Ferraiolo N, Greninger P, Borgmann K, Settleman J, Benes C, Sequist L, Zou L, Willers H
    Cancer Res, 0;73(20):6254-63.  0
  180. Mechanisms of resistance to high and low linear energy transfer radiation in myeloid leukemia cells.
    Authors: Haro K, Scott A, Scheinberg D
    Blood, 0;120(10):2087-97.  0
  181. Molecular and cellular pharmacology of the hypoxia-activated prodrug TH-302.
    Authors: Meng F, Evans J, Bhupathi D, Banica M, Lan L, Lorente G, Duan J, Cai X, Mowday A, Guise C, Maroz A, Anderson R, Patterson A, Stachelek G, Glazer P, Matteucci M, Hart C
    Mol Cancer Ther, 0;11(3):740-51.  0
  182. Viral DNA replication-dependent DNA damage response activation during BK polyomavirus infection.
    Authors: Verhalen B, Justice J, Imperiale M, Jiang M
    J Virol, 0;89(9):5032-9.  0
  183. Therapeutic targeting of BRCA1-mutated breast cancers with agents that activate DNA repair.
    Authors: Alli E, Solow-Cordero D, Casey S, Ford J
    Cancer Res, 0;74(21):6205-15.  0
  184. (212)Pb-radioimmunotherapy induces G(2) cell-cycle arrest and delays DNA damage repair in tumor xenografts in a model for disseminated intraperitoneal disease.
    Authors: Yong K, Milenic D, Baidoo K, Brechbiel M
    Mol Cancer Ther, 0;11(3):639-48.  0
  185. Doxorubicin and vincristine affect undifferentiated rat spermatogonia.
    Authors: Beaud H, van Pelt A, Delbes G
    Reproduction, 0;153(6):725-735.  0
  186. Thirdhand smoke causes DNA damage in human cells.
    Authors: Hang B, Sarker A, Havel C, Saha S, Hazra T, Schick S, Jacob P, Rehan V, Chenna A, Sharan D, Sleiman M, Destaillats H, Gundel L
    Mutagenesis, 0;28(4):381-91.  0
  187. The RASSF1A tumor suppressor regulates XPA-mediated DNA repair.
    Authors: Donninger H, Clark J, Rinaldo F, Nelson N, Barnoud T, Schmidt M, Hobbing K, Vos M, Sils B, Clark G
    Mol Cell Biol, 0;35(1):277-87.  0
  188. MERIT40 cooperates with BRCA2 to resolve DNA interstrand cross-links.
    Authors: Jiang Q, Paramasivam M, Aressy B, Wu J, Bellani M, Tong W, Seidman M, Greenberg R
    Genes Dev, 0;29(18):1955-68.  0
  189. DNA-PK triggers histone ubiquitination and signaling in response to DNA double-strand breaks produced during the repair of transcription-blocking topoisomerase I lesions.
    Authors: Cristini A, Park J, Capranico G, Legube G, Favre G, Sordet O
    Nucleic Acids Res, 0;0(0):.  0
  190. Ubiquitylation of Ku80 by RNF126 Promotes Completion of Nonhomologous End Joining-Mediated DNA Repair.
    Authors: Ishida N, Nakagawa T, Iemura S, Yasui A, Shima H, Katoh Y, Nagasawa Y, Natsume T, Igarashi K, Nakayama K
    Mol Cell Biol, 0;37(4):.  0
  191. Replication stress by Py-Im polyamides induces a non-canonical ATR-dependent checkpoint response.
    Authors: Martinez T, Phillips J, Karanja K, Polaczek P, Wang C, Li B, Campbell J, Dervan P
    Nucleic Acids Res, 0;42(18):11546-59.  0
  192. Role of intracellular calcium and NADPH oxidase NOX5-S in acid-induced DNA damage in Barrett's cells and Barrett's esophageal adenocarcinoma cells.
    Authors: Li D, Cao W
    Am J Physiol Gastrointest Liver Physiol, 0;306(10):G863-72.  0
  193. Gold nanostars mediated combined photothermal and photodynamic therapy and X-ray imaging for cancer theranostic applications.
    Authors: Wang L, Meng D, Hao Y, Zhao Y, Li D, Zhang B, Zhang Y, Zhang Z
    J Biomater Appl, 0;30(5):547-57.  0
  194. The Role of HMGB1 in Radioresistance of Bladder Cancer.
    Authors: Shrivastava S, Mansure J, Almajed W, Cury F, Ferbeyre G, Popovic M, Seuntjens J, Kassouf W
    Mol Cancer Ther, 0;15(3):471-9.  0
  195. Development of a Test Method for the Evaluation of DNA Damage in Mouse Spermatogonial Stem Cells.
    Authors: Jeon H, Yi J, Kim T, Oh Y, Lee H, Lee M, Bang J, Ko K, Ahn I, Ko K, Kim J, Park H, Lee J, Sohn S
    Toxicol Res, 0;33(2):107-118.  0
  196. DNA Damage Response and DNA Repair in Skeletal Myocytes From a Mouse Model of Spinal Muscular Atrophy.
    Authors: Fayzullina S, Martin L
    J Neuropathol Exp Neurol, 0;75(9):889-902.  0
  197. Resistance of glioblastoma-initiating cells to radiation mediated by the tumor microenvironment can be abolished by inhibiting transforming growth factor-beta.
    Authors: Hardee M, Marciscano A, Medina-Ramirez C, Zagzag D, Narayana A, Lonning S, Barcellos-Hoff M
    Cancer Res, 0;72(16):4119-29.  0
  198. Physiological modulation of endogenous BRCA1 p220 abundance suppresses DNA damage during the cell cycle.
    Authors: Dimitrov S, Lu D, Naetar N, Hu Y, Pathania S, Kanellopoulou C, Livingston D
    Genes Dev, 0;27(20):2274-91.  0
  199. Amplification of TLK2 Induces Genomic Instability via Impairing the G2-M Checkpoint.
    Authors: Kim J, Anurag M, Veeraraghavan J, Schiff R, Li K, Wang X
    Mol Cancer Res, 0;14(10):920-927.  0
  200. A nuclease that mediates cell death induced by DNA damage and poly(ADP-ribose) polymerase-1.
    Authors: Wang Y, An R, Umanah G, Park H, Nambiar K, Eacker S, Kim B, Bao L, Harraz M, Chang C, Chen R, Wang J, Kam T, Jeong J, Xie Z, Neifert S, Qian J, Andrabi S, Blackshaw S, Zhu H, Song H, Ming G, Dawson V, Dawson T
    Science, 0;354(6308):.  0
  201. Regulation of mitochondrial poly(ADP-Ribose) polymerase activation by the beta-adrenoceptor/cAMP/protein kinase A axis during oxidative stress.
    Authors: Brunyanszki A, Olah G, Coletta C, Szczesny B, Szabo C
    Mol Pharmacol, 0;86(4):450-62.  0
  202. Combining PARP-1 inhibition and radiation in Ewing sarcoma results in lethal DNA damage.
    Authors: Lee H, Yoon C, Schmidt B, Park D, Zhang A, Erkizan H, Toretsky J, Kirsch D, Yoon S
    Mol Cancer Ther, 0;12(11):2591-600.  0
  203. Triplex structures induce DNA double strand breaks via replication fork collapse in NER deficient cells.
    Authors: Kaushik Tiwari M, Adaku N, Peart N, Rogers F
    Nucleic Acids Res, 0;44(16):7742-54.  0
  204. DNA strand breaks, acute phase response and inflammation following pulmonary exposure by instillation to the diesel exhaust particle NIST1650b in mice.
    Authors: Kyjovska Z, Jacobsen N, Saber A, Bengtson S, Jackson P, Wallin H, Vogel U
    Mutagenesis, 0;30(4):499-507.  0
  205. CSB interacts with SNM1A and promotes DNA interstrand crosslink processing.
    Authors: Iyama T, Lee S, Berquist B, Gileadi O, Bohr V, Seidman M, McHugh P, Wilson D
    Nucleic Acids Res, 0;43(1):247-58.  0
  206. Hematopoietic stem cell dysfunction underlies the progressive lymphocytopenia in XLF/Cernunnos deficiency.
    Authors: Avagyan S, Churchill M, Yamamoto K, Crowe J, Li C, Lee B, Zheng T, Mukherjee S, Zha S
    Blood, 0;124(10):1622-5.  0
  207. Nuclear GIT2 is an ATM substrate and promotes DNA repair.
    Authors: Lu D, Cai H, Park S, Siddiqui S, Premont R, Schmalzigaug R, Paramasivam M, Seidman M, Bodogai I, Biragyn A, Daimon C, Martin B, Maudsley S
    Mol Cell Biol, 0;35(7):1081-96.  0
  208. Requirement for human Mps1/TTK in oxidative DNA damage repair and cell survival through MDM2 phosphorylation.
    Authors: Yu Z, Huang Y, Shieh S
    Nucleic Acids Res, 0;44(3):1133-50.  0
  209. Cdc14A and Cdc14B Redundantly Regulate DNA Double-Strand Break Repair.
    Authors: Lin H, Ha K, Lu G, Fang X, Cheng R, Zuo Q, Zhang P
    Mol Cell Biol, 0;35(21):3657-68.  0
  210. Inhibiting protein arginine deiminases has antioxidant consequences.
    Authors: Witalison E, Cui X, Hofseth A, Subramanian V, Causey C, Thompson P, Hofseth L
    J Pharmacol Exp Ther, 0;353(1):64-70.  0
  211. FOXO3 Transcription Factor Is Essential for Protecting Hematopoietic Stem and Progenitor Cells from Oxidative DNA Damage.
    Authors: Bigarella C, Li J, Rimmele P, Liang R, Sobol R, Ghaffari S
    J Biol Chem, 0;292(7):3005-3015.  0
  212. Developmental expression of Musashi-1 and Musashi-2 RNA-binding proteins during spermatogenesis: analysis of the deleterious effects of dysregulated expression.
    Authors: Sutherland J, Fraser B, Sobinoff A, Pye V, Davidson T, Siddall N, Koopman P, Hime G, McLaughlin E
    Biol Reprod, 0;90(5):92.  0
  213. Kub5-Hera, the human Rtt103 homolog, plays dual functional roles in transcription termination and DNA repair.
    Authors: Morales J, Richard P, Rommel A, Fattah F, Motea E, Patidar P, Xiao L, Leskov K, Wu S, Hittelman W, Chiang C, Manley J, Boothman D
    Nucleic Acids Res, 0;42(8):4996-5006.  0
  214. Uracil-DNA glycosylase expression determines human lung cancer cell sensitivity to pemetrexed.
    Authors: Weeks L, Fu P, Gerson S
    Mol Cancer Ther, 0;12(10):2248-60.  0
  215. Intracellular accumulation of indium ions released from nanoparticles induces oxidative stress, proinflammatory response and DNA damage.
    Authors: Tabei Y, Sonoda A, Nakajima Y, Biju V, Makita Y, Yoshida Y, Horie M
    J Biochem, 0;159(2):225-37.  0
  216. Stimulation of lactate receptor (HCAR1) affects cellular DNA repair capacity.
    Authors: Wagner W, Kania K, Ciszewski W
    DNA Repair (Amst), 0;52(0):49-58.  0
  217. Ablation of XP-V gene causes adipose tissue senescence and metabolic abnormalities.
    Authors: Chen Y, Harris R, Hatahet Z, Chou K
    Proc Natl Acad Sci U S A, 0;112(33):E4556-64.  0
  218. Tobacco exposure results in increased E6 and E7 oncogene expression, DNA damage and mutation rates in cells maintaining episomal human papillomavirus 16 genomes.
    Authors: Wei L, Griego A, Chu M, Ozbun M
    Carcinogenesis, 0;35(10):2373-81.  0
  219. Speckle-type POZ protein, SPOP, is involved in the DNA damage response.
    Authors: Zhang D, Wang H, Sun M, Yang J, Zhang W, Han S, Xu B
    Carcinogenesis, 0;35(8):1691-7.  0
  220. Paternal DNA damage resulting from various sperm treatments persists after fertilization and is similar before and after DNA replication.
    Authors: Yamauchi Y, Riel J, Ward M
    J Androl, 0;33(2):229-38.  0
  221. HOXC10 Expression Supports the Development of Chemotherapy Resistance by Fine Tuning DNA Repair in Breast Cancer Cells.
    Authors: Sadik H, Korangath P, Nguyen N, Gyorffy B, Kumar R, Hedayati M, Teo W, Park S, Panday H, Munoz T, Menyhart O, Shah N, Pandita R, Chang J, Deweese T, Chang H, Pandita T, Sukumar S
    Cancer Res, 0;76(15):4443-56.  0
  222. Radioprotective properties of tocopherol succinate against ionizing radiation in mice.
    Authors: Singh V, Singh P, Wise S, Posarac A, Fatanmi O
    J Radiat Res, 0;54(2):210-20.  0
  223. Nek4 regulates entry into replicative senescence and the response to DNA damage in human fibroblasts.
    Authors: Nguyen C, Possemato R, Bauerlein E, Xie A, Scully R, Hahn W
    Mol Cell Biol, 0;32(19):3963-77.  0
  224. Differences in quantification of DNA double-strand breaks assessed by 53BP1/gammaH2AX focus formation assays and the comet assay in mammalian cells treated with irradiation and N-acetyl-L-cysteine.
    Authors: Kurashige T, Shimamura M, Nagayama Y
    J Radiat Res, 0;57(3):312-7.  0
  225. Sequential Combination Therapy of CDK Inhibition and Doxorubicin Is Synthetically Lethal in p53-Mutant Triple-Negative Breast Cancer.
    Authors: Jabbour-Leung N, Chen X, Bui T, Jiang Y, Yang D, Vijayaraghavan S, McArthur M, Hunt K, Keyomarsi K
    Mol Cancer Ther, 0;15(4):593-607.  0
  226. A role for the p53 tumour suppressor in regulating the balance between homologous recombination and non-homologous end joining.
    Authors: Moureau S, Luessing J, Harte E, Voisin M, Lowndes N
    Open Biol, 0;6(9):.  0
  227. A functional screen identifies miRNAs that inhibit DNA repair and sensitize prostate cancer cells to ionizing radiation.
    Authors: Hatano K, Kumar B, Zhang Y, Coulter J, Hedayati M, Mears B, Ni X, Kudrolli T, Chowdhury W, Rodriguez R, Deweese T, Lupold S
    Nucleic Acids Res, 0;43(8):4075-86.  0
  228. Engineered cellular gene-replacement platform for selective and inducible proteolytic profiling.
    Authors: Morgan C, Diaz J, Zeitlin S, Gray D, Wells J
    Proc Natl Acad Sci U S A, 0;112(27):8344-9.  0
  229. Silver nanoparticles: correlating nanoparticle size and cellular uptake with genotoxicity.
    Authors: Butler K, Peeler D, Casey B, Dair B, Elespuru R
    Mutagenesis, 0;30(4):577-91.  0
  230. Multiple isoforms of CDC25 oppose ATM activity to maintain cell proliferation during vertebrate development.
    Authors: Verduzco D, Dovey J, Shukla A, Kodym E, Skaug B, Amatruda J
    Mol Cancer Res, 0;10(11):1451-61.  0
  231. Androgen Deprivation Followed by Acute Androgen Stimulation Selectively Sensitizes AR-Positive Prostate Cancer Cells to Ionizing Radiation.
    Authors: Hedayati M, Haffner M, Coulter J, Raval R, Zhang Y, Zhou H, Mian O, Knight E, Razavi N, Dalrymple S, Isaacs J, Santos A, Hales R, Nelson W, Yegnasubramanian S, Deweese T
    Clin Cancer Res, 0;22(13):3310-3319.  0
  232. Lobarstin enhances chemosensitivity in human glioblastoma T98G cells.
    Authors: Kim S, Jo S, Lee H, Kim T, Kim I, Yim J, Chung H
    Anticancer Res, 0;33(12):5445-51.  0
  233. PNAS-4, an Early DNA Damage Response Gene, Induces S Phase Arrest and Apoptosis by Activating Checkpoint Kinases in Lung Cancer Cells.
    Authors: Yuan Z, Guo W, Yang J, Li L, Wang M, Lei Y, Wan Y, Zhao X, Luo N, Cheng P, Liu X, Nie C, Peng Y, Tong A, Wei Y
    J Biol Chem, 0;290(24):14927-44.  0
  234. LORD-Q: a long-run real-time PCR-based DNA-damage quantification method for nuclear and mitochondrial genome analysis.
    Authors: Lehle S, Hildebrand D, Merz B, Malak P, Becker M, Schmezer P, Essmann F, Schulze-Osthoff K, Rothfuss O
    Nucleic Acids Res, 0;42(6):e41.  0
  235. Poly(ADP-ribosyl)ation of FOXP3 Protein Mediated by PARP-1 Protein Regulates the Function of Regulatory T Cells.
    Authors: Luo X, Nie J, Wang S, Chen Z, Chen W, Li D, Hu H, Li B
    J Biol Chem, 0;290(48):28675-82.  0
  236. Caspase-9 is required for normal hematopoietic development and protection from alkylator-induced DNA damage in mice.
    Authors: Lu E, McLellan M, Ding L, Fulton R, Mardis E, Wilson R, Miller C, Westervelt P, DiPersio J, Link D, Walter M, Ley T, Graubert T
    Blood, 0;124(26):3887-95.  0
  237. Repair versus Checkpoint Functions of BRCA1 Are Differentially Regulated by Site of Chromatin Binding.
    Authors: Goldstein M, Kastan M
    Cancer Res, 0;75(13):2699-707.  0
  238. Repair of DNA Damage Induced by the Cytidine Analog Zebularine Requires ATR and ATM in Arabidopsis.
    Authors: Liu C, Finke A, Diaz M, Rozhon W, Poppenberger B, Baubec T, Pecinka A
    Plant Cell, 0;27(6):1788-800.  0
  239. hSSB1 (NABP2/ OBFC2B) is required for the repair of 8-oxo-guanine by the hOGG1-mediated base excision repair pathway.
    Authors: Paquet N, Adams M, Leong V, Ashton N, Touma C, Gamsjaeger R, Cubeddu L, Beard S, Burgess J, Bolderson E, O'Byrne K, Richard D
    Nucleic Acids Res, 0;43(18):8817-29.  0
  240. Hypoxic stress facilitates acute activation and chronic downregulation of fanconi anemia proteins.
    Authors: Scanlon S, Glazer P
    Mol Cancer Res, 0;12(7):1016-28.  0
  241. Unbiased compound screening identifies unexpected drug sensitivities and novel treatment options for gastrointestinal stromal tumors.
    Authors: Boichuk S, Lee D, Mehalek K, Makielski K, Wozniak A, Seneviratne D, Korzeniewski N, Cuevas R, Parry J, Brown M, Zewe J, Taguchi T, Kuan S, Schoffski P, Debiec-Rychter M, Duensing A
    Cancer Res, 0;74(4):1200-13.  0
  242. DNA damage in human skin keratinocytes caused by multiwalled carbon nanotubes with carboxylate functionalization.
    Authors: McShan D, Yu H
    Toxicol Ind Health, 0;30(6):489-98.  0
  243. Cytokine overproduction and crosslinker hypersensitivity are unlinked in Fanconi anemia macrophages.
    Authors: Garbati M, Hays L, Rathbun R, Jillette N, Chin K, Al-Dhalimy M, Agarwal A, Newell A, Olson S, Bagby G
    J Leukoc Biol, 0;99(3):455-65.  0
  244. A ubiquitylation site in Cockayne syndrome B required for repair of oxidative DNA damage, but not for transcription-coupled nucleotide excision repair.
    Authors: Ranes M, Boeing S, Wang Y, Wienholz F, Menoni H, Walker J, Encheva V, Chakravarty P, Mari P, Stewart A, Giglia-Mari G, Snijders A, Vermeulen W, Svejstrup J
    Nucleic Acids Res, 0;44(11):5246-55.  0
  245. miR-155 Overexpression Promotes Genomic Instability by Reducing High-fidelity Polymerase Delta Expression and Activating Error-Prone DSB Repair.
    Authors: Czochor J, Sulkowski P, Glazer P
    Mol Cancer Res, 0;14(4):363-73.  0
  246. Role of the Exocyst Complex Component Sec6/8 in Genomic Stability.
    Authors: Torres M, Pandita R, Kulak O, Kumar R, Formstecher E, Horikoshi N, Mujoo K, Hunt C, Zhao Y, Lum L, Zaman A, Yeaman C, White M, Pandita T
    Mol Cell Biol, 0;35(21):3633-45.  0
  247. CUX2 protein functions as an accessory factor in the repair of oxidative DNA damage.
    Authors: Pal R, Ramdzan Z, Kaur S, Duquette P, Marcotte R, Leduy L, Davoudi S, Lamarche-Vane N, Iulianella A, Nepveu A
    J Biol Chem, 0;290(37):22520-31.  0
  248. BCL2 suppresses PARP1 function and nonapoptotic cell death.
    Authors: Dutta C, Day T, Kopp N, van Bodegom D, Davids M, Ryan J, Bird L, Kommajosyula N, Weigert O, Yoda A, Fung H, Brown J, Shapiro G, Letai A, Weinstock D
    Cancer Res, 0;72(16):4193-203.  0
  249. Cyclin E1 deregulation occurs early in secretory cell transformation to promote formation of fallopian tube-derived high-grade serous ovarian cancers.
    Authors: Karst A, Jones P, Vena N, Ligon A, Liu J, Hirsch M, Etemadmoghadam D, Bowtell D, Drapkin R
    Cancer Res, 0;74(4):1141-52.  0
  250. Methylation of histone H4 lysine 20 by PR-Set7 ensures the integrity of late replicating sequence domains in Drosophila.
    Authors: Li Y, Armstrong R, Duronio R, MacAlpine D
    Nucleic Acids Res, 0;44(15):7204-18.  0
  251. PTH1-34 blocks radiation-induced osteoblast apoptosis by enhancing DNA repair through canonical Wnt pathway.
    Authors: Chandra A, Lin T, Zhu J, Tong W, Huo Y, Jia H, Zhang Y, Liu X, Cengel K, Xia B, Qin L
    J Biol Chem, 0;290(1):157-67.  0
  252. BRG1 promotes the repair of DNA double-strand breaks by facilitating the replacement of RPA with RAD51.
    Authors: Qi W, Wang R, Chen H, Wang X, Xiao T, Boldogh I, Ba X, Han L, Zeng X
    J Cell Sci, 0;128(2):317-30.  0
  253. UV Damage-Induced Phosphorylation of HBO1 Triggers CRL4DDB2-Mediated Degradation To Regulate Cell Proliferation.
    Authors: Matsunuma R, Niida H, Ohhata T, Kitagawa K, Sakai S, Uchida C, Shiotani B, Matsumoto M, Nakayama K, Ogura H, Shiiya N, Kitagawa M
    Mol Cell Biol, 0;36(3):394-406.  0
  254. Tumor radiosensitization by monomethyl auristatin E: mechanism of action and targeted delivery.
    Authors: Buckel L, Savariar E, Crisp J, Jones K, Hicks A, Scanderbeg D, Nguyen Q, Sicklick J, Lowy A, Tsien R, Advani S
    Cancer Res, 0;75(7):1376-1387.  0
  255. HT-COMET: a novel automated approach for high throughput assessment of human sperm chromatin quality.
    Authors: Albert O, Reintsch W, Chan P, Robaire B
    Hum Reprod, 0;31(5):938-46.  0
  256. A hormone-DNA repair circuit governs the response to genotoxic insult.
    Authors: Goodwin J, Schiewer M, Dean J, Schrecengost R, de Leeuw R, Han S, Ma T, Den R, Dicker A, Feng F, Knudsen K
    Cancer Discov, 0;3(11):1254-71.  0
  257. Cytidine deaminase Apobec3a induction in fallopian epithelium after exposure to follicular fluid.
    Authors: Brachova P, Alvarez N, Van Voorhis B, Christenson L
    Gynecol Oncol, 0;145(3):577-583.  0
  258. hMOF acetylation of DBC1/CCAR2 prevents binding and inhibition of SirT1.
    Authors: Zheng H, Yang L, Peng L, Izumi V, Koomen J, Seto E, Chen J
    Mol Cell Biol, 0;33(24):4960-70.  0
  259. Unique epigenetic influence of H2AX phosphorylation and H3K56 acetylation on normal stem cell radioresponses.
    Authors: Jacobs K, Misri S, Meyer B, Raj S, Zobel C, Sleckman B, Hallahan D, Sharma G
    Mol Biol Cell, 0;27(8):1332-45.  0
  260. Sequential combination therapy of ovarian cancer with degradable N-(2-hydroxypropyl)methacrylamide copolymer paclitaxel and gemcitabine conjugates.
    Authors: Zhang R, Yang J, Sima M, Zhou Y, Kopecek J
    Proc Natl Acad Sci U S A, 0;111(33):12181-6.  0
  261. miR-101 Enhances Cisplatin-Induced DNA Damage Through Decreasing Nicotinamide Adenine Dinucleotide Phosphate Levels by Directly Repressing Tp53-Induced Glycolysis and Apoptosis Regulator Expression in Prostate Cancer Cells.
    Authors: Huang S, Yang Z, Ma Y, Yang Y, Wang S
    DNA Cell Biol, 0;36(4):303-310.  0
  262. Role of MRE11 in cell proliferation, tumor invasion, and DNA repair in breast cancer.
    Authors: Yuan S, Hou M, Hsieh Y, Huang C, Lee Y, Chen Y, Lo S
    J Natl Cancer Inst, 0;104(19):1485-502.  0
  263. Sirt6 Promotes DNA End Joining in iPSCs Derived from Old Mice.
    Authors: Chen W, Liu N, Zhang H, Zhang H, Qiao J, Jia W, Zhu S, Mao Z, Kang J
    Cell Rep, 0;18(12):2880-2892.  0
  264. Sperm fucosyltransferase-5 mediates spermatozoa-oviductal epithelial cell interaction to protect human spermatozoa from oxidative damage.
    Authors: Huang V, Lee C, Lee Y, Lam K, Ko J, Yeung W, Ho P, Chiu P
    Mol Hum Reprod, 0;21(6):516-26.  0
  265. Mitochondrial reactive oxygen species are scavenged by Cockayne syndrome B protein in human fibroblasts without nuclear DNA damage.
    Authors: Cleaver J, Brennan-Minnella A, Swanson R, Fong K, Chen J, Chou K, Chen Y, Revet I, Bezrookove V
    Proc Natl Acad Sci U S A, 0;111(37):13487-92.  0
  266. The contribution of mitochondrial thymidylate synthesis in preventing the nuclear genome stress.
    Authors: Lee M, Wang L, Chang Z
    Nucleic Acids Res, 0;42(8):4972-84.  0
  267. Up-regulation of miR-1245 by c-myc targets BRCA2 and impairs DNA repair.
    Authors: Song L, Dai T, Xie Y, Wang C, Lin C, Wu Z, Ying Z, Wu J, Li M, Li J
    J Mol Cell Biol, 0;4(2):108-17.  0
  268. CREB-binding protein regulates Ku70 acetylation in response to ionization radiation in neuroblastoma.
    Authors: Subramanian C, Hada M, Opipari A, Castle V, Kwok R
    Mol Cancer Res, 0;11(2):173-81.  0
  269. Human single-stranded DNA binding protein 1 (hSSB1/NABP2) is required for the stability and repair of stalled replication forks.
    Authors: Bolderson E, Petermann E, Croft L, Suraweera A, Pandita R, Pandita T, Helleday T, Khanna K, Richard D
    Nucleic Acids Res, 0;42(10):6326-36.  0
  270. Inhibition of autophagy as a strategy to augment radiosensitization by the dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235.
    Authors: Cerniglia G, Karar J, Tyagi S, Christofidou-Solomidou M, Rengan R, Koumenis C, Maity A
    Mol Pharmacol, 0;82(6):1230-40.  0
  271. Effects of corexit oil dispersants and the WAF of dispersed oil on DNA damage and repair in cultured human bronchial airway cells, BEAS-2B.
    Authors: Major D, Derbes R, Wang H, Roy-Engel A
    Gene Rep, 0;3(0):22-30.  0
  272. RUG3 and ATM synergistically regulate the alternative splicing of mitochondrial nad2 and the DNA damage response in Arabidopsis thaliana.
    Authors: Su C, Zhao H, Zhao Y, Ji H, Wang Y, Zhi L, Li X
    Sci Rep, 0;7(0):43897.  0
  273. Quantitative proteomics profiling of murine mammary gland cells unravels impact of annexin-1 on DNA damage response, cell adhesion, and migration.
    Authors: Swa H, Blackstock W, Lim L, Gunaratne J
    Mol Cell Proteomics, 0;11(8):381-93.  0
  274. RAD51 plays a crucial role in halting cell death program induced by ionizing radiation in bovine oocytes.
    Authors: Kujjo L, Ronningen R, Ross P, Pereira R, Rodriguez R, Beyhan Z, Goissis M, Baumann T, Kagawa W, Camsari C, Smith G, Kurumizaka H, Yokoyama S, Cibelli J, Perez G
    Biol Reprod, 0;86(3):76.  0
  275. Glucocorticoids induce production of reactive oxygen species/reactive nitrogen species and DNA damage through an iNOS mediated pathway in breast cancer.
    Authors: Flaherty R, Owen M, Fagan-Murphy A, Intabli H, Healy D, Patel A, Allen M, Patel B, Flint M
    Breast Cancer Res, 0;19(1):35.  0
  276. Depletion of the chromatin remodeler CHD4 sensitizes AML blasts to genotoxic agents and reduces tumor formation.
    Authors: Sperlazza J, Rahmani M, Beckta J, Aust M, Hawkins E, Wang S, Zu Zhu S, Podder S, Dumur C, Archer K, Grant S, Ginder G
    Blood, 0;126(12):1462-72.  0
  277. Replication fork integrity and intra-S phase checkpoint suppress gene amplification.
    Authors: Kondratova A, Watanabe T, Marotta M, Cannon M, Segall A, Serre D, Tanaka H
    Nucleic Acids Res, 0;43(5):2678-90.  0
  278. NEO212, temozolomide conjugated to perillyl alcohol, is a novel drug for effective treatment of a broad range of temozolomide-resistant gliomas.
    Authors: Cho H, Wang W, Jhaveri N, Lee D, Sharma N, Dubeau L, Schonthal A, Hofman F, Chen T
    Mol Cancer Ther, 0;13(8):2004-17.  0
  279. Potential new mechanisms of placental damage in celiac disease: anti-transglutaminase antibodies impair human endometrial angiogenesis.
    Authors: Di Simone N, De Spirito M, Di Nicuolo F, Tersigni C, Castellani R, Silano M, Maulucci G, Papi M, Marana R, Scambia G, Gasbarrini A
    Biol Reprod, 0;89(4):88.  0
  280. Long-term exposure to diesel engine exhaust induces primary DNA damage: a population-based study.
    Authors: Duan H, Jia X, Zhai Q, Ma L, Wang S, Huang C, Wang H, Niu Y, Li X, Dai Y, Yu S, Gao W, Chen W, Zheng Y
    Occup Environ Med, 0;73(2):83-90.  0
  281. Endoglin (CD105) contributes to platinum resistance and is a target for tumor-specific therapy in epithelial ovarian cancer.
    Authors: Ziebarth A, Nowsheen S, Steg A, Shah M, Katre A, Dobbin Z, Han H, Lopez-Berestein G, Sood A, Conner M, Yang E, Landen C
    Clin Cancer Res, 0;19(1):170-82.  0
  282. Resveratrol sensitizes acute myelogenous leukemia cells to histone deacetylase inhibitors through reactive oxygen species-mediated activation of the extrinsic apoptotic pathway.
    Authors: Yaseen A, Chen S, Hock S, Rosato R, Dent P, Dai Y, Grant S
    Mol Pharmacol, 0;82(6):1030-41.  0
  283. USP1 targeting impedes GBM growth by inhibiting stem cell maintenance and radioresistance.
    Authors: Lee J, Chang N, Yoon Y, Yang H, Cho H, Kim E, Shin Y, Kang W, Oh Y, Mun G, Joo K, Nam D, Lee J
    Neuro Oncol, 0;18(1):37-47.  0
  284. Oncolytic virus-mediated manipulation of DNA damage responses: synergy with chemotherapy in killing glioblastoma stem cells.
    Authors: Kanai R, Rabkin S, Yip S, Sgubin D, Zaupa C, Hirose Y, Louis D, Wakimoto H, Martuza R
    J Natl Cancer Inst, 0;104(1):42-55.  0
  285. NQO1-Mediated Tumor-Selective Lethality and Radiosensitization for Head and Neck Cancer.
    Authors: Li L, Reddy S, Lin Z, Liu S, Park H, Chun S, Bornmann W, Thibodeaux J, Yan J, Chakrabarti G, Xie X, Sumer B, Boothman D, Yordy J
    Mol Cancer Ther, 0;15(7):1757-67.  0
  286. A panel of in vitro tests to evaluate genotoxic and morphological neoplastic transformation potential on Balb/3T3 cells by pristine and remediated titania and zirconia nanoparticles.
    Authors: Stoccoro A, Di Bucchianico S, Uboldi C, Coppede F, Ponti J, Placidi C, Blosi M, Ortelli S, Costa A, Migliore L
    Mutagenesis, 0;31(5):511-29.  0
  287. Identification of potentially cytotoxic lesions induced by UVA photoactivation of DNA 4-thiothymidine in human cells.
    Authors: Reelfs O, Macpherson P, Ren X, Xu Y, Karran P, Young A
    Nucleic Acids Res, 0;39(22):9620-32.  0
  288. Tight regulation of ubiquitin-mediated DNA damage response by USP3 preserves the functional integrity of hematopoietic stem cells.
    Authors: Lancini C, van den Berk P, Vissers J, Gargiulo G, Song J, Hulsman D, Serresi M, Tanger E, Blom M, Vens C, van Lohuizen M, Jacobs H, Citterio E
    J Exp Med, 0;211(9):1759-77.  0
  289. Augmentation of response to chemotherapy by microRNA-506 through regulation of RAD51 in serous ovarian cancers.
    Authors: Liu G, Yang D, Rupaimoole R, Pecot C, Sun Y, Mangala L, Li X, Ji P, Cogdell D, Hu L, Wang Y, Rodriguez-Aguayo C, Lopez-Berestein G, Shmulevich I, De Cecco L, Chen K, Mezzanzanica D, Xue F, Sood A, Zhang W
    J Natl Cancer Inst, 0;107(7):.  0
  290. Intracellular deoxyribonucleotide pool imbalance and DNA damage in cells treated with hydroxyurea, an inhibitor of ribonucleotide reductase.
    Authors: Osterman Golkar S, Czene S, Gokarakonda A, Haghdoost S
    Mutagenesis, 0;28(6):653-60.  0
  291. c-Myc-miR-29c-REV3L signalling pathway drives the acquisition of temozolomide resistance in glioblastoma.
    Authors: Luo H, Chen Z, Wang S, Zhang R, Qiu W, Zhao L, Peng C, Xu R, Chen W, Wang H, Chen Y, Yang J, Zhang X, Zhang S, Chen D, Wu W, Zhao C, Cheng G, Jiang T, Lu D, You Y, Liu N, Wang H
    Brain, 0;138(0):3654-72.  0
  292. A dual role of BRCA1 in two distinct homologous recombination mediated repair in response to replication arrest.
    Authors: Feng Z, Zhang J
    Nucleic Acids Res, 0;40(2):726-38.  0
  293. Preclinical activity profile and therapeutic efficacy of the HSP90 inhibitor ganetespib in triple-negative breast cancer.
    Authors: Proia D, Zhang C, Sequeira M, Jimenez J, He S, Spector N, Shapiro G, Tolaney S, Nagai M, Acquaviva J, Smith D, Sang J, Bates R, El-Hariry I
    Clin Cancer Res, 0;20(2):413-24.  0
  294. Nedd8-activating enzyme inhibitor MLN4924 provides synergy with mitomycin C through interactions with ATR, BRCA1/BRCA2, and chromatin dynamics pathways.
    Authors: Garcia K, Blank J, Bouck D, Liu X, Sappal D, Hather G, Cosmopoulos K, Thomas M, Kuranda M, Pickard M, Liu R, Bandi S, Smith P, Lightcap E
    Mol Cancer Ther, 0;13(6):1625-35.  0
  295. Characterizing Requirements for Small Ubiquitin-like Modifier (SUMO) Modification and Binding on Base Excision Repair Activity of Thymine-DNA Glycosylase in Vivo.
    Authors: McLaughlin D, Coey C, Yang W, Drohat A, Matunis M
    J Biol Chem, 0;291(17):9014-24.  0
  296. Cell cycle stage-specific roles of Rad18 in tolerance and repair of oxidative DNA damage.
    Authors: Yang Y, Durando M, Smith-Roe S, Sproul C, Greenwalt A, Kaufmann W, Oh S, Hendrickson E, Vaziri C
    Nucleic Acids Res, 0;41(4):2296-312.  0
  297. PKR inhibits the DNA damage response, and is associated with poor survival in AML and accelerated leukemia in NHD13 mice.
    Authors: Cheng X, Byrne M, Brown K, Konopleva M, Kornblau S, Bennett R, May W
    Blood, 0;126(13):1585-94.  0
  298. 2'-Fluoro-modified phosphorothioate oligonucleotide can cause rapid degradation of P54nrb and PSF.
    Authors: Shen W, Liang X, Sun H, Crooke S
    Nucleic Acids Res, 0;43(9):4569-78.  0
  299. Trifluridine Induces p53-Dependent Sustained G2 Phase Arrest with Its Massive Misincorporation into DNA and Few DNA Strand Breaks.
    Authors: Matsuoka K, Iimori M, Niimi S, Tsukihara H, Watanabe S, Kiyonari S, Kiniwa M, Ando K, Tokunaga E, Saeki H, Oki E, Maehara Y, Kitao H
    Mol Cancer Ther, 0;14(4):1004-13.  0
  300. Disruption of DNA Damage-Response by Propyl Gallate and 9-Aminoacridine.
    Authors: Matsuda S, Matsuda Y, Yanagisawa S, Ikura M, Ikura T, Matsuda T
    Toxicol Sci, 0;151(2):224-35.  0
  301. Induction of DNA damage signaling upon Rift Valley fever virus infection results in cell cycle arrest and increased viral replication.
    Authors: Baer A, Austin D, Narayanan A, Popova T, Kainulainen M, Bailey C, Kashanchi F, Weber F, Kehn-Hall K
    J Biol Chem, 0;287(10):7399-410.  0
  302. PKCalpha and HMGB1 antagonistically control hydrogen peroxide-induced poly-ADP-ribose formation.
    Authors: Andersson A, Bluwstein A, Kumar N, Teloni F, Traenkle J, Baudis M, Altmeyer M, Hottiger M
    Nucleic Acids Res, 0;44(16):7630-45.  0
  303. A novel role for the mono-ADP-ribosyltransferase PARP14/ARTD8 in promoting homologous recombination and protecting against replication stress.
    Authors: Nicolae C, Aho E, Choe K, Constantin D, Hu H, Lee D, Myung K, Moldovan G
    Nucleic Acids Res, 0;43(6):3143-53.  0
  304. WWOX, the common fragile site FRA16D gene product, regulates ATM activation and the DNA damage response.
    Authors: Abu-Odeh M, Salah Z, Herbel C, Hofmann T, Aqeilan R
    Proc Natl Acad Sci U S A, 0;111(44):E4716-25.  0
  305. Aspirin inhibits the SHH/GLI1 signaling pathway and sensitizes malignant glioma cells to temozolomide therapy.
    Authors: Ming J, Sun B, Li Z, Lin L, Meng X, Han B, Wang R, Wu P, Li J, Cai J, Jiang C
    Aging (Albany NY), 0;9(4):1233-1247.  0
  306. XPD-dependent activation of apoptosis in response to triplex-induced DNA damage.
    Authors: Kaushik Tiwari M, Rogers F
    Nucleic Acids Res, 0;41(19):8979-94.  0
  307. Stem Cell-Soluble Signals Enhance Multilumen Formation in SMG Cell Clusters.
    Authors: Maruyama C, Leigh N, Nelson J, McCall A, Mellas R, Lei P, Andreadis S, Baker O
    J Dent Res, 0;94(11):1610-7.  0
  308. The TMPRSS2-ERG Gene Fusion Blocks XRCC4-Mediated Nonhomologous End-Joining Repair and Radiosensitizes Prostate Cancer Cells to PARP Inhibition.
    Authors: Chatterjee P, Choudhary G, Alswillah T, Xiong X, Heston W, Magi-Galluzzi C, Zhang J, Klein E, Almasan A
    Mol Cancer Ther, 0;14(8):1896-906.  0
  309. Human papillomavirus type 16 E6* induces oxidative stress and DNA damage.
    Authors: Williams V, Filippova M, Filippov V, Payne K, Duerksen-Hughes P
    J Virol, 0;88(12):6751-61.  0
  310. Overexpression of HPV16 E6* Alters beta-Integrin and Mitochondrial Dysfunction Pathways in Cervical Cancer Cells.
    Authors: Evans W, Filippova M, Filippov V, Bashkirova S, Zhang G, Reeves M, Duerksen-Hughes P
    Cancer Genomics Proteomics, 0;13(4):259-73.  0
  311. ATM regulates NF-kappaB-dependent immediate-early genes via RelA Ser 276 phosphorylation coupled to CDK9 promoter recruitment.
    Authors: Fang L, Choudhary S, Zhao Y, Edeh C, Yang C, Boldogh I, Brasier A
    Nucleic Acids Res, 0;42(13):8416-32.  0
  312. ATDC (Ataxia Telangiectasia Group D Complementing) Promotes Radioresistance through an Interaction with the RNF8 Ubiquitin Ligase.
    Authors: Yang H, Palmbos P, Wang L, Kim E, Ney G, Liu C, Prasad J, Misek D, Yu X, Ljungman M, Simeone D
    J Biol Chem, 0;290(45):27146-57.  0
  313. Linking Cancer Metabolism to DNA Repair and Accelerated Senescence.
    Authors: Efimova E, Takahashi S, Shamsi N, Wu D, Labay E, Ulanovskaya O, Weichselbaum R, Kozmin S, Kron S
    Mol Cancer Res, 0;14(2):173-84.  0
  314. Nucleotide excision repair-dependent DNA double-strand break formation and ATM signaling activation in mammalian quiescent cells.
    Authors: Wakasugi M, Sasaki T, Matsumoto M, Nagaoka M, Inoue K, Inobe M, Horibata K, Tanaka K, Matsunaga T
    J Biol Chem, 0;289(41):28730-7.  0
  315. The Opposing Actions of Arabidopsis CHROMOSOME TRANSMISSION FIDELITY7 and WINGS APART-LIKE1 and 2 Differ in Mitotic and Meiotic Cells.
    Authors: De K, Bolanos-Villegas P, Mitra S, Yang X, Homan G, Jauh G, Makaroff C
    Plant Cell, 0;28(2):521-36.  0
  316. The retinoblastoma tumor suppressor modulates DNA repair and radioresponsiveness.
    Authors: Thangavel C, Boopathi E, Ciment S, Liu Y, O'Neill R, Sharma A, McMahon S, Mellert H, Addya S, Ertel A, Birbe R, Fortina P, Dicker A, Knudsen K, Den R
    Clin Cancer Res, 0;20(21):5468-5482.  0
  317. Innate inflammation induced by the 8-oxoguanine DNA glycosylase-1-KRAS-NF-kappaB pathway.
    Authors: Aguilera-Aguirre L, Bacsi A, Radak Z, Hazra T, Mitra S, Sur S, Brasier A, Ba X, Boldogh I
    J Immunol, 0;193(9):4643-53.  0
  318. Environmentally Relevant Concentrations of Arsenite Induce Dose-Dependent Differential Genotoxicity Through Poly(ADP-Ribose) Polymerase Inhibition and Oxidative Stress in Mouse Thymus Cells.
    Authors: Xu H, Zhou X, Wen X, Lauer F, Liu K, Hudson L, Aleksunes L, Burchiel S
    Toxicol Sci, 0;149(1):31-41.  0


  1. Are there other dyes beside SYBR Gold that can be used in the Comet Assay?

    • Yes, other dyes that can be substituted for SYBR Gold in staining solution for the Comet Assay. The important parameters to consider in choosing a DNA stain for the comet assay are similar fluorescence and decay rates for single-and  double-strand DNA. See Appendix C in the product insert for a table of DNA stains parameters. R&D Systems selected SYBR Gold dye due to the high background to noise ratio. It is the responsibility of the end-users to optimize the use of an alternative dye chosen for the Comet Assay.

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