Klotho beta is expressed primarily in the liver and pancreas and functions as a cofactor for FGF-19 subfamily member interactions with their receptors. It facilitates human FGF-19 (mouse FGF-15) binding to FGF R4 in the liver to inhibit bile acid synthesis. It also enhances FGF-21 binding to FGF R1c in adipocytes, leading to increased Insulin-dependent glucose uptake.
Cynomolgus Monkey Klotho beta (EHH53620.1) VersaClone cDNA
R&D Systems | Catalog # RDC3033
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Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: Klotho beta
Alternate Names
KLB
Gene Symbol
KLB
UniProt
Additional Klotho beta Products
Product Documents for Cynomolgus Monkey Klotho beta (EHH53620.1) VersaClone cDNA
Certificate of Analysis
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Note: Certificate of Analysis not available for kit components.
Product Specific Notices for Cynomolgus Monkey Klotho beta (EHH53620.1) VersaClone cDNA
For research use only
Related Research Areas
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