Cynomolgus Monkey OX40 (XP_005545179) VersaClone cDNA Summary
OX40 (CD134; TNFRSF4) is a T cell costimulatory molecule of the TNF receptor superfamily that coordinates with other costimulators (CD28, CD40, CD30, CD27 and 4-1BB) to manage the activation of the immune response. OX40 is upregulated on antigen activated CD4+ and CD8+ T cells with costimulation by CD40-CD40 Ligand and CD28-B7. OX40 interactions with OX40 Ligand on antigen presenting cells enhances T cell survival, proliferation, and cytokine production. It also inhibits the conversion of effector T cells into regulatory T cells (Tregs) and can promote the maintenance of and recall response in memory T cells. OX40 is constitutively expressed on Tregs where it promotes Treg proliferation and immunosuppressive activity. OX40-OX40 Ligand signaling is involved in allergic airway inflammation, graft-versus-host disease, and autoimmune disease.
No product specific FAQs exist for this product, however you mayView all cDNA Clone FAQs
Reviews for Cynomolgus Monkey OX40 (XP_005545179) VersaClone cDNA
There are currently no reviews for this product. Be the first to review Cynomolgus Monkey OX40 (XP_005545179) VersaClone cDNA and earn rewards!
Have you used Cynomolgus Monkey OX40 (XP_005545179) VersaClone cDNA?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image