Dcp1a Antibody

Novus Biologicals | Catalog # NB100-2830

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Western Blot, Peptide ELISA

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG
View all Dcp1a Primary Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-QVLTKNKDNHN corresponding to C-Terminus according to NP_060873.3.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for Dcp1a Antibody

Western Blot: Dcp1a Antibody [NB100-2830]

Western Blot: Dcp1a Antibody [NB100-2830]

Western Blot: Dcp1a Antibody [NB100-2830] - Staining of lysate of cell line A431 (35 ug protein in RIPA buffer). Antibody at 1 ug/mL. Detected by chemiluminescence.

Applications for Dcp1a Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:6000

Western Blot

1 - 3 ug/mL
Application Notes
WB: Approx. 75 kDa band observed in human lysates of A431 and HeLa (calculated MW of 63.3 kDa band according to NP_060873.3).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Dcp1a

Decapping is a key step in general and regulated mRNA decay. The protein encoded by this gene is a decapping enzyme. This protein and another decapping enzyme form a decapping complex, which interacts with the nonsense-mediated decay factor hUpf1 and may be recruited to mRNAs containing premature termination codons. This protein also participates in the TGF-beta signaling pathway.

Alternate Names

DCP1 decapping enzyme homolog A (S. cerevisiae), decapping enzyme hDcp1a, EC 3.-, FLJ21691, mRNA-decapping enzyme 1A, Nbla00360, putative protein product of Nbla00360, Smad4-interacting transcriptional co-activator, SMAD4IP1, SMIFHSA275986, Transcription factor SMIF

Entrez Gene IDs

55802 (Human); 75901 (Mouse)

Gene Symbol

DCP1A

UniProt

NP_060873.3 (Human)

Additional Dcp1a Products

Product Documents for Dcp1a Antibody

Certificate of Analysis

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Product Specific Notices for Dcp1a Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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