Desmocollin-1 Antibody - BSA Free

Novus Biologicals | Catalog # NBP2-62695

Novus Biologicals
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all Desmocollin-1 Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: RQVILQVGVINEAQFSKAASSQTPTMCTTTVTVKIIDSDEGPECHPPVKVIQSQDGFPAGQELLGYKALDPEISSGEGLRYQKLGDEDNWFEINQHTG

Reactivity Notes

Mouse (80%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Desmocollin-1 Antibody - BSA Free

Immunohistochemistry-Paraffin: Desmocollin-1 Antibody [NBP2-62695]

Immunohistochemistry-Paraffin: Desmocollin-1 Antibody [NBP2-62695]

Immunohistochemistry-Paraffin: Desmocollin-1 Antibody [NBP2-62695] - Staining of human Placenta shows no positivity in trophoblastic cells as expected.
Immunohistochemistry-Paraffin: Desmocollin-1 Antibody [NBP2-62695]

Immunohistochemistry-Paraffin: Desmocollin-1 Antibody [NBP2-62695]

Immunohistochemistry-Paraffin: Desmocollin-1 Antibody [NBP2-62695] - Analysis in human skin and pancreas tissues using Anti-DSC1 antibody. Corresponding DSC1 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: Desmocollin-1 Antibody [NBP2-62695]

Immunohistochemistry-Paraffin: Desmocollin-1 Antibody [NBP2-62695]

Immunohistochemistry-Paraffin: Desmocollin-1 Antibody [NBP2-62695] - Staining of human skin shows high expression.
Immunohistochemistry-Paraffin: Desmocollin-1 Antibody [NBP2-62695]

Immunohistochemistry-Paraffin: Desmocollin-1 Antibody [NBP2-62695]

Immunohistochemistry-Paraffin: Desmocollin-1 Antibody [NBP2-62695] - Staining of human hair shows strong membranous and cytoplasmic positivity in internal root sheath.
Immunohistochemistry-Paraffin: Desmocollin-1 Antibody [NBP2-62695]

Immunohistochemistry-Paraffin: Desmocollin-1 Antibody [NBP2-62695]

Immunohistochemistry-Paraffin: Desmocollin-1 Antibody [NBP2-62695] - Staining of human pancreas shows low expression as expected.
Immunohistochemistry-Paraffin: Desmocollin-1 Antibody [NBP2-62695]

Immunohistochemistry-Paraffin: Desmocollin-1 Antibody [NBP2-62695]

Immunohistochemistry-Paraffin: Desmocollin-1 Antibody [NBP2-62695] - Staining of human Endometrium shows no positivity in glandular cells as expected.
Immunohistochemistry-Paraffin: Desmocollin-1 Antibody [NBP2-62695]

Immunohistochemistry-Paraffin: Desmocollin-1 Antibody [NBP2-62695]

Immunohistochemistry-Paraffin: Desmocollin-1 Antibody [NBP2-62695] - Staining of human Pancreas shows no positivity in exocrine glandular cells as expected.
Immunohistochemistry-Paraffin: Desmocollin-1 Antibody [NBP2-62695]

Immunohistochemistry-Paraffin: Desmocollin-1 Antibody [NBP2-62695]

Immunohistochemistry-Paraffin: Desmocollin-1 Antibody [NBP2-62695] - Staining of human Skin shows strong membranous positivity in squamous epithelial cells.

Applications for Desmocollin-1 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Desmocollin-1

The protein encoded by the Desmosomal Protein gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Alternative splicing results in two transcript variants encoding distinct isoforms. (provided by RefSeq)

Alternate Names

CDHF1, Desmocollin1, DG2/DG3, DSC1

Gene Symbol

DSC1

Additional Desmocollin-1 Products

Product Documents for Desmocollin-1 Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for Desmocollin-1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

Cadherin Superfamily

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Protocols

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