Desmoglein-3 Antibody - BSA Free

Novus Biologicals | Catalog # NBP2-54744

Novus Biologicals
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Key Product Details

Validated by

Orthogonal Validation, Independent Antibodies

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all Desmoglein-3 Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed against a Recombinant Protein corresponding to amino acids: FRPASKTFTVQKGISSKKLVDYILGTYQAIDEDTNKAASNVKYVMGRNDGGYLMIDSKTAEIKFVKNMNRDSTFIVNKTITAEVLAIDEYTGKTSTGTVYVRVPDFND

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (80%), Rat (81%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Novus Biologicals Rabbit Desmoglein-3 Antibody - BSA Free (NBP2-54744) is a polyclonal antibody validated for use in IHC. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for Desmoglein-3 Antibody - BSA Free

Immunohistochemistry-Paraffin: Desmoglein-3 Antibody [NBP2-54744]

Immunohistochemistry-Paraffin: Desmoglein-3 Antibody [NBP2-54744]

Immunohistochemistry-Paraffin: Desmoglein-3 Antibody [NBP2-54744] - Staining of human testis.
Immunohistochemistry-Paraffin: Desmoglein-3 Antibody [NBP2-54744]

Immunohistochemistry-Paraffin: Desmoglein-3 Antibody [NBP2-54744]

Immunohistochemistry-Paraffin: Desmoglein-3 Antibody [NBP2-54744] - Staining of human esophagus shows high expression.
Immunohistochemistry-Paraffin: Desmoglein-3 Antibody [NBP2-54744]

Immunohistochemistry-Paraffin: Desmoglein-3 Antibody [NBP2-54744]

Immunohistochemistry-Paraffin: Desmoglein-3 Antibody [NBP2-54744] - Staining of human stomach shows low expression as expected.
Immunohistochemistry-Paraffin: Desmoglein-3 Antibody [NBP2-54744]

Immunohistochemistry-Paraffin: Desmoglein-3 Antibody [NBP2-54744]

Immunohistochemistry-Paraffin: Desmoglein-3 Antibody [NBP2-54744] - Staining in human esophagus and stomach tissues using anti-DSG3 antibody. Corresponding DSG3 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: Desmoglein-3 Antibody [NBP2-54744]

Immunohistochemistry-Paraffin: Desmoglein-3 Antibody [NBP2-54744]

Immunohistochemistry-Paraffin: Desmoglein-3 Antibody [NBP2-54744] - Staining of human colon, esophagus, lymph node and testis using Anti-DSG3 antibody NBP2-54744 (A) shows similar protein distribution across tissues to independent antibody NBP2-54729 (B).
Immunohistochemistry-Paraffin: Desmoglein-3 Antibody [NBP2-54744]

Immunohistochemistry-Paraffin: Desmoglein-3 Antibody [NBP2-54744]

Immunohistochemistry-Paraffin: Desmoglein-3 Antibody [NBP2-54744] - Staining of human lymph node.
Immunohistochemistry-Paraffin: Desmoglein-3 Antibody [NBP2-54744]

Immunohistochemistry-Paraffin: Desmoglein-3 Antibody [NBP2-54744]

Immunohistochemistry-Paraffin: Desmoglein-3 Antibody [NBP2-54744] - Staining of human colon.

Applications for Desmoglein-3 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Desmoglein-3

Desmoglein 3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.

Alternate Names

CDHF6, Desmoglein3, DSG3

Gene Symbol

DSG3

Additional Desmoglein-3 Products

Product Documents for Desmoglein-3 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for Desmoglein-3 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

Adhesion Molecules
Cadherin Superfamily

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Protocols

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