Dicer Antibody (CL0378)

Novus Biologicals | Catalog # NBP3-52092

Recombinant Monoclonal Antibody
Novus Biologicals
100% Guarantee

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Mouse IgG2A Clone # CL0378
View all Dicer Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed using a recombinant protein derived from Q9UPY3, with the exact immunogen sequence remaining proprietary.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Scientific Data Images for Dicer Antibody (CL0378)

Dicer Antibody (CL0378) Western Blot: Dicer Antibody (CL0378) [NBP3-52092]

Western Blot: Dicer Antibody (CL0378) [NBP3-52092]

Analysis in RT-4 cells transfected with control siRNA, target specific siRNA probe #1 and #2,. Remaining relative intensity is presented. Loading control: Anti-GAPDH.
Dicer Antibody (CL0378) Immunohistochemistry: Dicer Antibody (CL0378) [NBP3-52092]

Immunohistochemistry: Dicer Antibody (CL0378) [NBP3-52092]

Staining of human breast cancer shows moderate cytoplasmic positivity in tumor cells.
Dicer Antibody (CL0378) Immunohistochemistry: Dicer Antibody (CL0378) [NBP3-52092]

Immunohistochemistry: Dicer Antibody (CL0378) [NBP3-52092]

Staining of human colorectal cancer shows moderate cytoplasmic positivity in tumor cells.
Dicer Antibody (CL0378) Immunohistochemistry: Dicer Antibody (CL0378) [NBP3-52092]

Immunohistochemistry: Dicer Antibody (CL0378) [NBP3-52092]

Staining of human testis shows moderate to strong cytoplasmic positivity in a subset of cells in seminiferous ducts.
Dicer Antibody (CL0378) Immunohistochemistry: Dicer Antibody (CL0378) [NBP3-52092]

Immunohistochemistry: Dicer Antibody (CL0378) [NBP3-52092]

Staining of human endometrium shows moderate cytoplasmic positivity in glandular cells.
Dicer Antibody (CL0378) Immunohistochemistry: Dicer Antibody (CL0378) [NBP3-52092]

Immunohistochemistry: Dicer Antibody (CL0378) [NBP3-52092]

Staining of human cerebral cortex shows moderate cytoplasmic positivity in neurons.

Applications for Dicer Antibody (CL0378)

Application
Recommended Usage

Immunohistochemistry

1:50-1:200

Immunohistochemistry-Paraffin

1:50-1:200

Western Blot

1 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Dicer

Dicer encodes a protein possessing an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. The encoded protein functions as a ribonuclease and is required by the RNA interference and small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq]

Alternate Names

DCR1, DICER, dicer 1, double-stranded RNA-specific endoribonuclease, dicer 1, ribonuclease type III, Dicer1, Dcr-1 homolog (Drosophila), EC 3.1.26, EC 3.1.26.-, EC 3.1.26.3, Helicase MOI, Helicase with RNase motif, helicase-moi, HERNADicer1, Dcr-1 homolog, K12H4.8-LIKE, KIAA0928endoribonuclease Dicer

Gene Symbol

DICER1

Additional Dicer Products

Product Documents for Dicer Antibody (CL0378)

Certificate of Analysis

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Product Specific Notices for Dicer Antibody (CL0378)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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