DLG1 Antibody

Novus Biologicals | Catalog # NBP1-20907

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Western Blot, Peptide ELISA

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG
View all DLG1 Primary Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-NSKTRDKGEIPDD corresponding to internal region according to NP_001091894.1, NP_004078.2.

Epitope

C terminus

Specificity

This antibody is expected to recognize both reported isoforms (NP_001091894.1and NP_004078.2).

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for DLG1 Antibody

Western Blot: DLG1 Antibody [NBP1-20907]

Western Blot: DLG1 Antibody [NBP1-20907]

Western Blot: DLG1 Antibody [NBP1-20907] - (0.3ug/ml) staining of KELLY lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for DLG1 Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:16000

Western Blot

0.3 - 1 ug/ml
Application Notes
WB: Approx. 150 kDa band observed in KELLY lysate (calculated MW of 103 kDa band according to NP_004078.2). The observed molecular weight corresponds to earlier findings with different antibodies from other sources.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: DLG1

DLG1(disks large homolog 1), also known as SAP97(synapse-associated protein 97), is a scaffolding protein that contains three PDZ domains, one SH3 domain, one L27 domain, and one guanylate kinase-like domain. DLG1has been found to control ion channel clustering at post-synaptic densities in neural cells and to also play a role in adherens junction assembly, and the recruitment of signaling molecules to discreet plasma membrane domains.

Alternate Names

discs, large homolog 1 (Drosophila), disks large homolog 1, DKFZp761P0818, DKFZp781B0426, hDlg, large (Drosophila) homolog 1, presynaptic protein SAP97

Entrez Gene IDs

1739 (Human); 13383 (Mouse); 25252 (Rat)

Gene Symbol

DLG1

UniProt

NP_001091894.1 (Human)

Additional DLG1 Products

Product Documents for DLG1 Antibody

Certificate of Analysis

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Product Specific Notices for DLG1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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