Catalog Number: 2312
Chemical Name: 6,7-Dinitroquinoxaline-2,3-dione disodium salt
Biological Activity
Water-soluble form of DNQX (Cat. No. 0189). Selective non-NMDA receptor antagonist.
Technical Data
  • M.Wt:
    296.1
  • Formula:
    C8H2N4O6Na2
  • Solubility:
    Soluble to 100 mM in water
  • Purity:
    >98%
  • Storage:
    Desiccate at RT
  • CAS No:
    1312992-24-7
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Quinoxalinediones: potent competitive non-NMDA glutamate receptor antagonists.
    Honore et al.
    Science, 1988;241:701
  2. Structure-activity relationships in the development of excitatory amino acid receptor agonists and competitive antagonists.
    Watkins et al.
    TiPS, 1990;11:25
Citations:

The citations listed below are publications that use Tocris products. Selected citations for DNQX disodium salt include:

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  1. Postnatal development of the electrophysiological properties of somatostatin interneurons in the anterior cingulate cortex of mice.
    Authors: Pan Et al.
    J Neurosci 2016;6:28137
  2. Absence of plateau potentials in dLGN cells leads to a breakdown in retinogeniculate refinement.
    Authors: Dilger Et al.
    J Neurosci 2015;35:3652
  3. Giant ankyrin-G stabilizes somatodendritic GABAergic synapses through opposing endocytosis of GABAA receptors.
    Authors: Tseng Et al.
    Sci Rep 2015;112:1214
  4. Retinal input to efferent target amacrine cells in the avian retina.
    Authors: Lindstrom Et al.
    Proc Natl Acad Sci U S A 2010;27:103
  5. Transient change in GABA(A) receptor subunit mRNA expression in Lurcher cerebellar nuclei during Purkinje cell degeneration.
    Authors: Linnemann Et al.
    Vis Neurosci 2006;7:59
Tocris Small Molecules
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DNQX

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