Fc gamma RIIA/CD32a Antibody (3B6) - BSA Free

Novus Biologicals | Catalog # NBP3-26587

Recombinant Monoclonal Antibody
Novus Biologicals
100% Guarantee

Key Product Details

Species Reactivity

Human

Applications

Western Blot, ELISA

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 3B6 expressed in HEK293

Format

BSA Free
View all Fc gamma RIIA/CD32a Primary Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from Human Fc gamma RIIA/CD32a [UniProt P12318]

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Fc gamma RIIA/CD32a Antibody (3B6) - BSA Free

Fc gamma RIIA/CD32a Antibody (3B6)

Western Blot: Fc gamma RIIA/CD32a Antibody (3B6) [NBP3-26587] -

Western Blot: Fc gamma RIIA/CD32a Antibody (3B6) [NBP3-26587] - Positive Western Blot detected in: THP-1 whole cell lysate.
All lanes: Fc gamma RIIA/CD32a Antibody at 1: 1000
Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution.
Predicted band size: 35, 36 kDa
Observed band size: 45 kDa

Applications for Fc gamma RIIA/CD32a Antibody (3B6) - BSA Free

Application
Recommended Usage

Western Blot

1:500-1:5000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, and 50% glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20 to -70C. Avoid freeze-thaw cycles.

Background: Fc gamma RIIA/CD32a

The FCGR2A gene encodes a low affinity immunoglobulin gamma Fc region receptor II-a protein that in isoform 1 is 317 amino acids long at 35 kDA and at isoform 2 is 316 amino acids long at nearly 35 kDA. These proteins are found on the surface of many immune system response cells that act as a low affinity receptor through encouraging responses against pathogens and soluble antigens. Additionally, it functions to initiate phagocytosis of opsonized antigens. FCGR2A participates in Fc-GammaR pathway, osteoclast differentiation, signaling events controlled by PTP1B, and NFAT in immune response. It is known to interact with genes SYK, FYN, HCK, LGALS3, and PIK3R1. FCGR2A is linked to lupus, thrombocytopenia, b-cell lymphomas, otitis media, adult-onset still's disease, guillain-barre syndrome, asymptomatic dengue, severe acute respiratory syndrome.

Long Name

Fc gamma Receptor II A

Alternate Names

CD32a, FCGR2A, FcgRIIA, FCRIIA

Gene Symbol

FCGR2A

Additional Fc gamma RIIA/CD32a Products

Product Documents for Fc gamma RIIA/CD32a Antibody (3B6) - BSA Free

Certificate of Analysis

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Product Specific Notices for Fc gamma RIIA/CD32a Antibody (3B6) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs for Fc gamma RIIA/CD32a Antibody (3B6) - BSA Free

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  • Q: Does any of your FCGR2A antibodies (19C10, 6D11, 13G9) cross react to FCGR2B?

    A: For these antibodies, we have used the full-length protein FCGR2A (NP_067674) as the immunogen and we have not mapped the epitope that is detected with each Ab yet. I did an alignment of these two proteins and they are highly conserved thus it seems likely that there will be cross-reactivity.

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