Fetal Bovine Serum - Charcoal/Dextran Treated

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Catalog # Availability Size / Price Qty
S11610
S11650
S11695
Fetal Bovine Serum - Charcoal/Dextran Treated
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Fetal Bovine Serum - Charcoal/Dextran Treated Summary

Charcoal-stripped Fetal Bovine Serum is used in applications requiring lower levels of hormones, steroids or growth factors in serum, such as insulin and estrogen related research.

Key Benefits

• Utilizes a proprietary and efficacious charcoal/dextran treatment
• All lots are verified for reduced hormeones, steroids, and lipid-like components
• Excellent cell growth characteristics and low endotoxin
• USDA-Approved FBS of Mexico/Central American origin
• Manufactured in our ISO 9001:2015 certified facility
• Formerly sold under the Atlanta Biologicals brand

Why Use FBS - Charcoal/Dextran Treated?

Pre-selected high quality Fetal Bovine Serum, also known as Fetal Calf Serum (FCS), is processed using a proprietary Charcoal/Dextran treatment proven to reduce the levels of many hormones, steroids, and other lipid-like components. Each lot produced is tested for various hormones and steroids before and after treatment to confirm the efficacy of the process. All lots of Charcoal/Dextran Treated FBS are manufactured in our ISO 9001:2015 certified facility.

Fetal Bovine Serum and other serum products should be stored and handled correctly to assure long-term stability and to preserve growth performance consistency throughout its shelf-life. In addition, heat inactivation of serum is frequently desired to inactivate complement within the serum. Below are protocol links for serum storage/handling and heat inactivation.

Protocol for Fetal Bovine Serum Storage, Thawing, and Freezing.
Protocol for Heat Inactivation of Serum Products.

Collection, Processing, and Testing of R&D Systems FBS

Collection and Processing - R&D Systems FBS is manufactured under a process that meets USDA requirements for animal products and ensures the product is traceable back to the date and location of collection. Our FBS manufacturing adheres to closed-system collection, processing in positive pressure, HEPA-filtered clean rooms, and triple 0.1 um filtration to remove contaminants. Strict control of the process from collection through processing enables us to provide a stable, consistent performing, and traceable supply of quality serum throughout global fluctuations in serum availability and regulatory requirements.

Virus Testing - Fetal Bovine Serum – Charcoal/Dextran Treated undergoes testing for adventitious viruses, such as: Bovine Viral Diarrhea Virus (BVDV), Infectious Bovine Rhinotracheitis Virus (IBRV), Parainfluenza-3 Virus (PI-3V), Bluetongue Virus (BTV), Bovine Respiratory Syncytial Virus (BRSV), Bovine Parvovirus (BPV), Bovine Adenovirus, Type 3 (BAV-3), Bovine Adenovirus, Type 5 (BAV-5), Reo virus, and Rabies virus.

Biochemical Testing - R&D Systems FBS undergo biochemical profiling including total protein, albumin, globulin, IgG, total bilirubin, glucose, iron, cholesterol, triglycerides, sodium and potassium. View the product insert for a complete list of biochemical profiling components, which may vary between grades.

Chemical Analysis - Each lot of FBS is tested for osmolality, pH, hemoglobin, endotoxin (LAL method) and microbiological contamination (using methods recommended by the U.S. Pharmacopeia).

Specifications

Osmolality
260 -350 mOsm
Purification
Triple 0.1 μm filtered
Sterility Testing
Pass
Testing Additional
pH - 6.5-8.5

Endotoxin - ≤ 50.0 EU/mL by Limulus Amebocyte Lysate (LAL) Assay

Hemoglobin - 25 mg/dL
Hormone Profile - Insulin, Estradiol,, Cortisol, Progesterone, Testosterone, T4, and T3
Shipping Conditions
On Dry Ice
Storage
-5 to -20 °C
Applications
Cell Culture
Species
Bovine
Country of Origin
UNITED STATES

Limitations

For research use only. Not for diagnositic use.

Product Datasheets

Data Example

Fetal Bovine Serum - Charcoal/Dextran Treated

Reagents Provided

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