Use of Cultrex Basement Membrane Extract to Improve Take and Growth of Xenografts in Mice

This protocol outlines methods and tips to improve mouse xenograft studies using Cultrex® Basement Membrane Extract (BME). Some specific tips and considerations you can find in this protocol include:

  • Tumor tissue processing and injection tips to improve initiation of tumor cells in mouse xenografts
  • Considerations for xenograft injection site, optimizing cell number, and identifying mouse strains
  • Use of Cultrex BME to enhance the tumor cell take and growth in xenograft studies in mice

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Organoid and 3-D Cell Culture Protocols