FGF activity is mediated by a family of type I transmembrane tyrosine kinases, which undergo dimerization and autophosphorylation after ligand binding. Five distinct genes encode closely related FGF receptors, FGFR1 through 5. FGFRs contain three Ig-like domains and a stretch of acidic residues between the first and second Ig-like domains. FGFR1, 2, 3, and -4 have a cytoplasmic split tyrosine-kinase domain, but FGFR5 does not. Multiple forms of FGFR1, 2, and 3 are generated by alternative splicing.
FGFR2 Antibody - BSA Free
Novus Biologicals | Catalog # NBP1-88670
![Immunohistochemistry-Paraffin: FGFR2 Antibody [NBP1-88670]](https://resources.rndsystems.com/images/products/FGF-R2-Antibody-Immunohistochemistry-Paraffin-NBP1-88670-img0004.jpg "Immunohistochemistry-Paraffin: FGFR2 Antibody [NBP1-88670]")
Loading...
Key Product Details
Species Reactivity
Validated:
Human, Mouse
Cited:
Mouse
Predicted:
Rat (91%). Backed by our 100% Guarantee.
Applications
Validated:
Immunohistochemistry, Immunohistochemistry-Paraffin
Cited:
IF/IHC
Label
Unconjugated
Antibody Source
Polyclonal Rabbit IgG
Format
BSA Free
Loading...
Product Specifications
Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: PPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMV
Reactivity Notes
Mouse reactivity reported in scientific literature (PMID: 25035393).
Clonality
Polyclonal
Host
Rabbit
Isotype
IgG
Scientific Data Images for FGFR2 Antibody - BSA Free
Immunohistochemistry-Paraffin: FGFR2 Antibody [NBP1-88670]
Immunohistochemistry-Paraffin: FGF R2 Antibody [NBP1-88670] - Staining of human prostate shows moderate membranous positivity in glandular cells and weak cytoplasmic staining of smooth muscle cells.![Immunohistochemistry-Paraffin: FGFR2 Antibody [NBP1-88670]](https://resources.rndsystems.com/images/products/FGF-R2-Antibody-Immunohistochemistry-Paraffin-NBP1-88670-img0002.jpg "Immunohistochemistry-Paraffin: FGFR2 Antibody [NBP1-88670]")
Immunohistochemistry-Paraffin: FGFR2 Antibody [NBP1-88670]
Immunohistochemistry-Paraffin: FGF R2 Antibody [NBP1-88670] - Staining of human Fallopian tube shows moderate membranous positivity in glandular cells.![Immunohistochemistry-Paraffin: FGFR2 Antibody [NBP1-88670]](https://resources.rndsystems.com/images/products/FGF-R2-Antibody-Immunohistochemistry-Paraffin-NBP1-88670-img0003.jpg "Immunohistochemistry-Paraffin: FGFR2 Antibody [NBP1-88670]")
Immunohistochemistry-Paraffin: FGFR2 Antibody [NBP1-88670]
Immunohistochemistry-Paraffin: FGF R2 Antibody [NBP1-88670] - Staining of human endometrium shows moderate membranous positivity in glandular cells.![Immunohistochemistry-Paraffin: FGFR2 Antibody [NBP1-88670]](https://resources.rndsystems.com/images/products/FGF-R2-Antibody-Immunohistochemistry-Paraffin-NBP1-88670-img0005.jpg "Immunohistochemistry-Paraffin: FGFR2 Antibody [NBP1-88670]")
Immunohistochemistry-Paraffin: FGFR2 Antibody [NBP1-88670]
Immunohistochemistry-Paraffin: FGF R2 Antibody [NBP1-88670] - Staining of human skeletal muscle shows low positivity as expected.Applications for FGFR2 Antibody - BSA Free
Application
Recommended Usage
Immunohistochemistry
1:20 - 1:50
Immunohistochemistry-Paraffin
1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Formulation, Preparation, and Storage
Purification
Affinity purified
Formulation
PBS (pH 7.2) and 40% Glycerol
Format
BSA Free
Preservative
0.02% Sodium Azide
Concentration
Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Background: FGFR2
Long Name
Fibroblast Growth Factor Receptor 2
Alternate Names
CD332, FGF R2
Entrez Gene IDs
2263 (Human)
Gene Symbol
FGFR2
UniProt
Additional FGFR2 Products
Product Documents for FGFR2 Antibody - BSA Free
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for FGFR2 Antibody - BSA Free
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
Citations for FGFR2 Antibody - BSA Free
Powered by Bioz
Customer Reviews for FGFR2 Antibody - BSA Free
There are currently no reviews for this product. Be the first to review FGFR2 Antibody - BSA Free and earn rewards!
Have you used FGFR2 Antibody - BSA Free?
Submit a review and receive an Amazon gift card!
$25/€18/£15/$25CAN/¥2500 Yen for a review with an image
$10/€7/£6/$10CAN/¥1110 Yen for a review without an image
Submit a review
Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
- Antigen Retrieval Protocol (PIER)
- Antigen Retrieval for Frozen Sections Protocol
- Appropriate Fixation of IHC/ICC Samples
- Cellular Response to Hypoxia Protocols
- Chromogenic IHC Staining of Formalin-Fixed Paraffin-Embedded (FFPE) Tissue Protocol
- Chromogenic Immunohistochemistry Staining of Frozen Tissue
- ClariTSA™ Fluorophore Kits
- Detection & Visualization of Antibody Binding
- Fluorescent IHC Staining of Frozen Tissue Protocol
- Graphic Protocol for Heat-induced Epitope Retrieval
- Graphic Protocol for the Preparation and Fluorescent IHC Staining of Frozen Tissue Sections
- Graphic Protocol for the Preparation and Fluorescent IHC Staining of Paraffin-embedded Tissue Sections
- Graphic Protocol for the Preparation of Gelatin-coated Slides for Histological Tissue Sections
- IHC Sample Preparation (Frozen sections vs Paraffin)
- Immunofluorescent IHC Staining of Formalin-Fixed Paraffin-Embedded (FFPE) Tissue Protocol
- Immunohistochemistry (IHC) and Immunocytochemistry (ICC) Protocols
- Immunohistochemistry Frozen Troubleshooting
- Immunohistochemistry Paraffin Troubleshooting
- Preparing Samples for IHC/ICC Experiments
- Preventing Non-Specific Staining (Non-Specific Binding)
- Primary Antibody Selection & Optimization
- Protocol for Heat-Induced Epitope Retrieval (HIER)
- Protocol for Making a 4% Formaldehyde Solution in PBS
- Protocol for VisUCyte™ HRP Polymer Detection Reagent
- Protocol for the Preparation & Fixation of Cells on Coverslips
- Protocol for the Preparation and Chromogenic IHC Staining of Frozen Tissue Sections
- Protocol for the Preparation and Chromogenic IHC Staining of Frozen Tissue Sections - Graphic
- Protocol for the Preparation and Chromogenic IHC Staining of Paraffin-embedded Tissue Sections
- Protocol for the Preparation and Chromogenic IHC Staining of Paraffin-embedded Tissue Sections - Graphic
- Protocol for the Preparation and Fluorescent IHC Staining of Frozen Tissue Sections
- Protocol for the Preparation and Fluorescent IHC Staining of Paraffin-embedded Tissue Sections
- Protocol for the Preparation of Gelatin-coated Slides for Histological Tissue Sections
- TUNEL and Active Caspase-3 Detection by IHC/ICC Protocol
- The Importance of IHC/ICC Controls
- Troubleshooting Guide: Immunohistochemistry
- View all Protocols, Troubleshooting, Illustrated assays and Webinars
Loading...
Associated Pathways
MAPK Signaling Pathway: Mitogen Stimulation Pathway
mTOR Signaling Pathway
