FOXE1 Antibody

Novus Biologicals | Catalog # NB100-1271

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Peptide ELISA

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG
View all FOXE1 Primary Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-AYPGGIDRFVSAM corresponding to C-Terminus according to NP_004464.2.

Localization

Nuclear

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for FOXE1 Antibody

Immunohistochemistry-Paraffin: FOXE1 Antibody [NB100-1271]

Immunohistochemistry-Paraffin: FOXE1 Antibody [NB100-1271]

Immunohistochemistry-Paraffin: FOXE1 Antibody [NB100-1271] - Staining of paraffin embedded Human Thyroid Gland. Steamed antigen retrieval with Tris/EDTA buffer pH 9, HRP-staining.
Immunohistochemistry-Paraffin: FOXE1 Antibody [NB100-1271]

Immunohistochemistry-Paraffin: FOXE1 Antibody [NB100-1271]

Immunohistochemistry-Paraffin: FOXE1 Antibody [NB100-1271] - Staining of paraffin embedded Human Testis. Steamed antigen retrieval with Tris/EDTA buffer pH 9, AP-staining.

Applications for FOXE1 Antibody

Application
Recommended Usage

Immunohistochemistry

2 - 5 ug/ml

Immunohistochemistry-Paraffin

2 - 5 ug/ml

Peptide ELISA

Detection limit 1:8000
Application Notes
WB: Preliminary experiments gave an approx. 70 kDa band in human thymus and thyroid gland lysates after 0.3 ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 38.1 kDa band according to NP_004464.2. The 70 kDa band was successfully blocked by incubation with the immunizing peptide. IHC: Paraffin embedded Human Thyroid Gland shows nuclear staining in thyrocytes. Paraffin embedded Human Testis.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: FOXE1

This intronless gene belongs to the forkhead family of transcription factors, which is characterized by a distinct forkhead domain. This gene functions as a thyroid transcription factor which likely plays a crucial role in thyroid morphogenesis. Mutations in this gene are associated with congenital hypothyroidism and cleft palate with thyroid dysgenesis. The map localization of this gene suggests it may also be a candidate gene for squamous cell epithelioma and hereditary sensory neuropathy type I.

Alternate Names

FKHL15HFKL5, forkhead box E1 (thyroid transcription factor 2), forkhead box E2, Forkhead box protein E2, forkhead, drosophila, homolog-like 15, Forkhead-related protein FKHL15, HFKH4Thyroid transcription factor 2, TITF2HNF-3/fork head-like protein 5, TTF2forkhead box protein E1, TTF-2FOXE2

Entrez Gene IDs

2304 (Human)

Gene Symbol

FOXE1

UniProt

NP_004464. (Human)

Additional FOXE1 Products

Product Documents for FOXE1 Antibody

Certificate of Analysis

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Product Specific Notices for FOXE1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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