FOXO4 Antibody

Novus Biologicals | Catalog # NB100-59745

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Western Blot, Peptide ELISA

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG
View all FOXO4 Primary Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-EAASQDRMPQDLD corresponding to internal region according to NP_005929.2.

Epitope

EAASQDRMPQDLD

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for FOXO4 Antibody

Western Blot: FOXO4 Antibody [NB100-59745]

Western Blot: FOXO4 Antibody [NB100-59745]

Western Blot: FOXO4 Antibody [NB100-59745] - Staining of K562 cell lysate (35 ug protein in RIPA buffer). Antibody at 1 ug/mL. Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for FOXO4 Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:64000

Western Blot

1 - 3 ug/mL

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: FOXO4

FOXO4 is a forkhead transcription factor involved in the regulation of the insulin signaling pathway. It binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. FOXO4 down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. It is also involved in negative regulation of the cell cycle.

Alternate Names

AFX, AFX1myeloid/lymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog);translocated to, 7, Fork head domain transcription factor AFX1, forkhead box O4, forkhead box protein O4, MLLT7MGC120490, myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila);translocated to, 7

Entrez Gene IDs

4303 (Human)

Gene Symbol

FOXO4

UniProt

NP_005929.2 (Human)

Additional FOXO4 Products

Product Documents for FOXO4 Antibody

Certificate of Analysis

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Product Specific Notices for FOXO4 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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