FRA-1/FOSL1 Antibody - BSA Free

Name: FRA-1/FOSL1 Antibody - BSA Free
Brand: Novus Biologicals
SKU: NBP2-57326
Price: 559 USD
Availability: InStock

Novus Biologicals | Catalog # NBP2-57326

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Product Specifications
Scientific Data
Applications
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Rat (96%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Chromatin Immunoprecipitation-exo-Seq

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

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Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: LVPSINTMSGSQELQWMVQPHFLGPSSYPRPLTYPQYSPPQPRPGVIRALGPPPGVRRRPCEQISPE

Reactivity Notes

Mouse 88%

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for FRA-1/FOSL1 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: FRA-1/FOSL1 Antibody [NBP2-57326]

Immunocytochemistry/Immunofluorescence: FRA-1/FOSL1 Antibody [NBP2-57326] - Staining of human cell line U-251 MG shows localization to nucleoplasm. Antibody staining is shown in green.

Chromatin Immunoprecipitation-exo-Seq: FRA-1/FOSL1 Antibody - BSA Free [NBP2-57326]

ChIP-Exo-Seq composite graph for Anti-FOSL1 (NBP2-57326) tested in K562 cells. Strand-specific reads (blue: forward, red: reverse) and IgG controls (black: forward, grey: reverse) are plotted against the distance from a composite set of reference binding sites. The antibody exhibits robust target enrichment compared to a non-specific IgG control and precisely reveals its structural organization around the binding site. Data generated by Prof. B. F. Pugh´s Lab at Cornell University.

Applications for FRA-1/FOSL1 Antibody - BSA Free

Application

Recommended Usage

Chromatin Immunoprecipitation-exo-Seq

1-10ug per reaction

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Application Notes

ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: FRA-1

The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.

Long Name

Fos-related antigen 1

Alternate Names

FOSL1, FRA1

Gene Symbol

FOSL1

Additional FRA-1 Products

Product Documents for FRA-1/FOSL1 Antibody - BSA Free

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Certificate of Analysis

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Product Specific Notices for FRA-1/FOSL1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.