GABA Transporter 2 Antibody - Azide and BSA Free

Novus Biologicals | Catalog # NBP2-47147

Novus Biologicals
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Key Product Details

Species Reactivity

Rat

Applications

Immunohistochemistry, Western Blot, ELISA

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

Azide and BSA Free
View all GABA Transporter 2 Primary Antibodies »

Product Specifications

Immunogen

A 15 residue synthetic peptide derived from C-terminal domain of rat GAT-2.

Specificity

Reacts with GAT-2 from rat, mouse and human central nervous system.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Applications for GABA Transporter 2 Antibody - Azide and BSA Free

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:500

Western Blot

1:200 - 1:5000

Formulation, Preparation, and Storage

Purification

Protein A purified

Reconstitution

Lyophilized powder, reconstituted in distilled water.

Formulation

0.1M Tris, 0.1M Glycine and 2% Sucrose

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: GABA Transporter 2

GABA is a major inhibitory neurotransmitter and the GABAergic transmission is terminated by the rapid Na+/Cl-dependent uptake of through GABA transporters. There are multiple subtypes of GABA transporters (GAT1, GAT2, GAT3; and betaine GABA transporter (BGT-1). There is ~50% homology between each subtypes. GAT1 and GAT3 have been detected in various parts of the brain while GAT2 is found in many tissues. It appears that GAT1 and GAT3 are involved in distinct GABAergic transmission while GAT2 may be important in non-neural functions. GAT2 is a gamma-amino butyric acid (GABA) transporter. It is a 602 amino acid (85kDa) transmembrane protein

Long Name

Sodium- and chloride-dependent GABA transporter 2

Alternate Names

GAT-2, GAT2, SLC6A13

Gene Symbol

SLC6A13

UniProt

P31646 (Rat)

Additional GABA Transporter 2 Products

Product Documents for GABA Transporter 2 Antibody - Azide and BSA Free

Certificate of Analysis

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Product Specific Notices for GABA Transporter 2 Antibody - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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