GDF-8/Myostatin Antibody (GDF9/4261)

Novus Biologicals | Catalog # NBP3-07706

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Western Blot, ELISA

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG Clone # GDF9/4261
View all GDF-8/Myostatin Primary Antibodies »

Product Specifications

Immunogen

Recognizes the 113 amino acid carboxy-terminal fragment of GDF-8/Myostatin protein (Uniprot: O14793)

Localization

Cytoplasmic (secreted)

Specificity

Myostatin is a well-characterized negative regulator of skeletal muscle and can inhibit myogenesis and stimulate adipogenesis. Clone Myo 2/1A has been shown to have the reverse effect, up- regulate myogenesis and down- regulate adipogenesis.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG

Theoretical MW

52 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

200ug/ml of antibody purified from Bioreactor Concentrate by Protein A or G. Prepared in 10 mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0 mg/ml. (NBP3-08680)

Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80 C.

Applications for GDF-8/Myostatin Antibody (GDF9/4261)

Application
Recommended Usage

Western Blot

1-2 ug/ml
Application Notes
ELISA: For coating, order antibody without BSA).
Optimal dilution for a specific application should be determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

10 mM PBS with 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: GDF-8/Myostatin

Myostatin (GDF8) is a negative regulator of muscle growth in mammals, and loss-of-function mutations are associated with increased skeletal-muscle mass in mice, cattle, and humans.

Long Name

Growth Differentiation Factor 8

Alternate Names

GDF8, MSLHP, MSTN, Myostatin

Gene Symbol

MSTN

UniProt

O14793 (Human)

Additional GDF-8/Myostatin Products

Product Documents for GDF-8/Myostatin Antibody (GDF9/4261)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for GDF-8/Myostatin Antibody (GDF9/4261)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs

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