GPIHBP1 Antibody [Biotin]

Novus Biologicals | Catalog # NB110-41539B

Novus Biologicals

Key Product Details

Species Reactivity

Human, Mouse

Applications

Western Blot, Immunocytochemistry/ Immunofluorescence

Label

Biotin

Antibody Source

Polyclonal Rabbit IgG
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Product Specifications

Immunogen

A synthetic peptide corresponding to an internal region [within residues 170-250] of mouse GPIHBP1. [Swiss-Prot# Q9D1N2]

Localization

Plasma membrane

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Applications for GPIHBP1 Antibody [Biotin]

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: GPIHBP1

GPI-anchored HDL-binding protein 1 (Gpihbp1) is a novel protein that may be involved in the regulation of the delivery of fats to cells for energy and storage. Digested fats travel to the small intestine, where they are packaged into chylomicrons (particles filled with triglycerides). Chylomicrons then travel through the bloodstream and deliver triglycerides to tissues that are hungry for fuel or to adipose tissue for energy storage. Triglycerides are broken down or hydrolyzed by the enzyme lipoprotein lipase (LpL). The triglyceride breakdown products are then taken up and used by cells. Gpihbp1 is the molecule in capillaries that facilitates the capture of chylomicrons and facilitates the interaction with LpL. It has been shown that fats in the bloodstream are not readily metabolized in the absence of GPIHBP1.

Long Name

Glycosylphosphatidylinositol Anchored High Density Lipoprotein Binding Protein 1

Alternate Names

GPI-Anchored HDL-Binding Protein 1, GPI-HBP1, HBP1, HYPL1D

Gene Symbol

GPIHBP1

Additional GPIHBP1 Products

Product Documents for GPIHBP1 Antibody [Biotin]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for GPIHBP1 Antibody [Biotin]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for GPIHBP1 Antibody [Biotin]

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  • Q: Can you recommend a streptavidin 647 secondary for biotinylated GPIHBP1 antibody NB110-41539B? Also, can I use another primary rabbit IgG antibody with an anti-Rabbit IgG secondary in the 561 nm channel along with this biotinylated GPIHBP1 or will the rabbit IgG host isotype cause issues?

    A: Ideally, you would not need a secondary for most applications. However, if you are looking for an anti-streptavidin that is conjugated with a "647" dye, I am afraid we do not have this dye available. If you are planning to use another antibody that is a rabbit polyclonal antibody, I would suggest not to use this pair, as this NB110-41539B is also rabbit polyclonal and it would cross react with the secondary antibody.

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