GPR17 Antibody - BSA Free

Novus Biologicals | Catalog # NBP3-46187

Novus Biologicals
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot, ELISA

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all GPR17 Primary Antibodies »

Product Specifications

Immunogen

G protein-coupled receptor 17. (Uniprot# Q13304)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

50 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for GPR17 Antibody - BSA Free

GPR17 Antibody - BSA Free

Western Blot: GPR17 Antibody - BSA Free [NBP3-46187] -

Western Blot: GPR17 Antibody - BSA Free [NBP3-46187] - Human serum tissue were subjected to SDS PAGE followed by western blot with (GPR17 antibody) at dilution of 1:300

Applications for GPR17 Antibody - BSA Free

Application
Recommended Usage

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS, 50% Glycerol, pH (7.3)

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: GPR17

GPR17, a former orphan G-coupled protein is specifically activated by P2Y and CysLT endogenous ligands, leading to both adenylyl cyclase inhibition and intracellular calcium increases. In both rats and humans GPR17 expressed in the organs which suffer ischemic damage, like the brain, heart and kidneys. Studies by Ciana, et. al. have shown that inhibition of GPR17 reduces ischemic damage in a rat focal ischemia model. These results suggest GPR17 is the common molecular target mediating brain damage by nucleotides and CysLTs.

Long Name

G Protein-coupled Receptor 17

Alternate Names

P2Y-like Receptor, R12, UDP/CysLT Receptor

Gene Symbol

GPR17

Additional GPR17 Products

Product Documents for GPR17 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for GPR17 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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