GPR3 Antibody - BSA Free

Novus Biologicals | Catalog # NBP1-02376

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human, Monkey, Primate

Predicted:

Equine (94%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, ELISA

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all GPR3 Primary Antibodies »

Product Specifications

Immunogen

Synthetic 17 amino acid peptide from N-terminal extracellular domain of human GPR3.

Epitope

N-Terminus extracellular domain

Reactivity Notes

Gorilla, Gibbon, Marmoset. Predicted cross-reactivity based on sequence identity: Bovine (88%), Rabbit (88%), Elephant (82%), Panda (82%), Porcine (82%).

Specificity

Human GPR3. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except CASKIN2 (53%), INPPL1 (47%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for GPR3 Antibody - BSA Free

Immunohistochemistry-Paraffin: GPR3 Antibody - BSA Free [NBP1-02376]

Immunohistochemistry-Paraffin: GPR3 Antibody - BSA Free [NBP1-02376]

Immunohistochemistry-Paraffin: GPR3 Antibody - BSA Free [NBP1-02376] - Staining of human brain after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

Applications for GPR3 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

10 ug/ml
Application Notes
.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.1% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: GPR3

GPR3 has been identified as a constitutively active lysophospholipid/lysosphingolipid receptor. GPR3 receptor is a link in communication between the somatic cells and oocyte of the ovarian follicle where GPR3 maintains meiotic arrest in mouse oocytes. Oocytes from Gpr3 knockout mice resume meiosis within antral follicles, independently of an increase in luteinizing hormone, and this phenotype Mice deficient in GPR3 exhibit premature ovarian failure due to early oocyte aging (Ledent et al. 2005).

Long Name

G Protein-coupled Receptor 3

Alternate Names

ACCA, G protein-coupled receptor 3

Entrez Gene IDs

2827 (Human)

Gene Symbol

GPR3

UniProt

P46089 (Human)

Additional GPR3 Products

Product Documents for GPR3 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for GPR3 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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