Granzyme family serine proteases are stored in the granules of cytotoxic T lymphocytes and natural killer cells. Granzymes contain one S1 protease domain and are synthesized as preproproteins. Granzymes are released toward pathogen infected or transformed target cells during cellular immune reactions. Target cell entry by granzymes is through perforin channels. Granzymes trigger apoptosis by caspase-dependent and -independent mechanisms. There are five granzymes (A, B, G, H and K) in human and many more in mouse and rat.
Monkey Granzyme B ELISA Kit (Colorimetric)
Novus Biologicals | Catalog # NBP3-11808
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Key Product Details
Sample Type & Volume Required Per Well
Serum, plasma and other biological fluids (100 uL)
Sensitivity
9.38 pg/mL
Assay Range
15.63 - 1000 pg/mL
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Product Specifications
Assay Type
Sandwich-ELISA
Kit Type
ELISA Kit (Colorimetric)
Species
Monkey
Precision
Intra-Assay Precision (Precision within an assay) %CV 6.68
Inter-Assay Precision (Precision between assays) %CV 5.73
Recovery for Monkey Granzyme B ELISA Kit (Colorimetric)
Recovery
83 - 105%
Linearity
Scientific Data Images for Monkey Granzyme B ELISA Kit (Colorimetric)
ELISA: Monkey Granzyme B ELISA Kit (Colorimetric) [NBP3-11808] -
ELISA: Monkey Granzyme B ELISA Kit (Colorimetric) [NBP3-11808] - Standard Curve ReferenceKit Contents for Monkey Granzyme B ELISA Kit (Colorimetric)
- Biotinylated Detection Antibody Diluent
- Concentrated Biotinylated Detection Antibody
- Concentrated HRP Conjugate
- Concentrated Wash Buffer
- HRP Conjugate Diluent
- Micro ELISA Plate
- Plate Sealer
- Reference Standard
- Reference Standard & Sample Diluent
- Stop Solution
- Substrate Reagent
Preparation and Storage
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Storage of components varies. See protocol for specific instructions.
Background: Granzyme B
Alternate Names
CGL-1, CGL1, CSPB, CTLA-1, CTLA1, CTSGL1, Fragmentin-2, Granzyme-2, GRB, GrzB, GZMB, HLP, SECT
Gene Symbol
GZMB
Additional Granzyme B Products
Product Documents for Monkey Granzyme B ELISA Kit (Colorimetric)
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for Monkey Granzyme B ELISA Kit (Colorimetric)
This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.
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