Granzyme M Antibody (D1) - BSA Free

Novus Biologicals | Catalog # NBP3-41198

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # D1

Format

BSA Free
View all Granzyme M Primary Antibodies »

Product Specifications

Immunogen

Immunized with recombinant Human Granzyme M (Uniprot#: P51124; Ile26-Ala257 (Uniprot#: P51124)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Scientific Data Images for Granzyme M Antibody (D1) - BSA Free

Granzyme M Antibody (D1)

Western Blot: Granzyme M Antibody (D1) [NBP3-41198] -

Western Blot: Granzyme M Antibody (D1) [NBP3-41198] - Sample: Recombinant Granzyme M, Human.
Granzyme M Antibody (D1)

Immunohistochemistry-Paraffin: Granzyme M Antibody (D1) [NBP3-41198] -

Immunohistochemistry-Paraffin: Granzyme M Antibody (D1) [NBP3-41198] - Vector Red staining on IHC-P; Samples: Human Tonsil Tissue; Primary Ab: 10ug/ml NBP3-41198; Second Ab: 2ug/mL HRP-Linked Caprine Anti-Mouse IgG Monoclonal Antibody

Applications for Granzyme M Antibody (D1) - BSA Free

Application
Recommended Usage

Immunohistochemistry

5-20ug/mL

Immunohistochemistry-Paraffin

5-20ug/mL

Western Blot

0.01-2ug/mL

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

0.01M PBS, pH7.4, 50% glycerol

Format

BSA Free

Preservative

0.05% Proclin 300

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Granzyme M

The GZMM gene encodes a 257 amino acid long, 27 kDA granzyme M protein that cleaves peptide substrates after methionine, leucine, and norleucine. In doing so, it encourages caspase activation and apoptosis of target cells. GZMM has been investigated for its role in arrhythmogenic right ventricular dysplasia as it participates in the immune system, alternative complement activation, and granzyme pathways. It is known to interact with genes CASP3, DFFA, EZR, NPM1, and PAK2.

Alternate Names

EC 3.4.21, EC 3.4.21.-, granzyme M, granzyme M (lymphocyte met-ase 1), HU-Met-1, LMET1, lymphocyte met-ase 1, Met-1 serine protease, MET1met-ase, Met-ase, Natural killer cell granular protease

Gene Symbol

GZMM

Additional Granzyme M Products

Product Documents for Granzyme M Antibody (D1) - BSA Free

Certificate of Analysis

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Product Specific Notices for Granzyme M Antibody (D1) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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