Key Product Details

Species Reactivity

Rat

Applications

Western Blot, Neutralization

Label

FITC (Excitation = 495 nm, Emission = 519 nm)

Antibody Source

Monoclonal Mouse IgG2A Clone # 198314
View all Growth Hormone R/GHR Primary Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant rat Growth Hormone R/GHR
Phe19-Arg265
Accession # P16310

Specificity

Detects rat Growth Hormone R/GHR in direct ELISAs and Western blots. In direct ELISAs and Western blots, 100% cross-reactivity with recombinant human GHR is observed, but no cross-reactivity with recombinant mouse GHR is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Applications for Growth Hormone R Antibody (198314) [FITC]

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Neutralization

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Growth Hormone R/GHR

Growth hormone receptor encodes a protein that is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. A common alternate allele of this gene, called GHRd3, lacks exon three and has been well-characterized. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. Other splice variants, including one encoding a soluble form of the protein (GHRtr), have been observed but have not been thoroughly characterized.

Long Name

Growth Hormone Receptor

Alternate Names

GHR

Gene Symbol

GHR

Additional Growth Hormone R/GHR Products

Product Documents for Growth Hormone R Antibody (198314) [FITC]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for Growth Hormone R Antibody (198314) [FITC]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs

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