HAAO Antibody - BSA Free

Novus Biologicals | Catalog # NBP1-85892

Novus Biologicals
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Key Product Details

Validated by

Orthogonal Validation, Independent Antibodies

Species Reactivity

Validated:

Human

Predicted:

Mouse (92%), Rat (94%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all HAAO Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: AWVKENRGSFQPPVCNKLMHQEQLKVMFVGGPNTRKDYHIEEGEEVFYQLEGDMVLRVLEQGKHRDVVIRQGEIFLLPARVPHSPQ

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for HAAO Antibody - BSA Free

Immunohistochemistry-Paraffin: HAAO Antibody [NBP1-85892]

Immunohistochemistry-Paraffin: HAAO Antibody [NBP1-85892]

Immunohistochemistry-Paraffin: HAAO Antibody [NBP1-85892] - Staining of human small intestine.
Immunohistochemistry-Paraffin: HAAO Antibody [NBP1-85892]

Immunohistochemistry-Paraffin: HAAO Antibody [NBP1-85892]

Immunohistochemistry-Paraffin: HAAO Antibody [NBP1-85892] - Staining of human liver shows high expression.
Immunohistochemistry-Paraffin: HAAO Antibody [NBP1-85892]

Immunohistochemistry-Paraffin: HAAO Antibody [NBP1-85892]

Immunohistochemistry-Paraffin: HAAO Antibody [NBP1-85892] - Staining in human liver and pancreas tissues using anti-HAAO antibody. Corresponding HAAO RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: HAAO Antibody [NBP1-85892]

Immunohistochemistry-Paraffin: HAAO Antibody [NBP1-85892]

Immunohistochemistry-Paraffin: HAAO Antibody [NBP1-85892] - Staining of human kidney, liver, small intestine and testis using Anti-HAAO antibody NBP1-85892 (A) shows similar protein distribution across tissues to independent antibody NBP2-48755 (B).
Immunohistochemistry-Paraffin: HAAO Antibody [NBP1-85892]

Immunohistochemistry-Paraffin: HAAO Antibody [NBP1-85892]

Immunohistochemistry-Paraffin: HAAO Antibody [NBP1-85892] - Staining of human kidney.
Immunohistochemistry-Paraffin: HAAO Antibody [NBP1-85892]

Immunohistochemistry-Paraffin: HAAO Antibody [NBP1-85892]

Immunohistochemistry-Paraffin: HAAO Antibody [NBP1-85892] - Staining of human testis.
HAAO Antibody - BSA Free Immunohistochemistry-Paraffin: HAAO Antibody - BSA Free [NBP1-85892]

Immunohistochemistry-Paraffin: HAAO Antibody - BSA Free [NBP1-85892]

Staining of human pancreas shows low expression as expected.

Applications for HAAO Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: HAAO

3-Hydroxyanthranilate 3,4-dioxygenase is a monomeric cytosolic protein belonging to the family of intramolecular dioxygenases containing nonheme ferrous iron. It is widely distributed in peripheral organs, such as liver and kidney, and is also present in low amounts in the central nervous system. HAAO catalyzes the synthesis of quinolinic acid (QUIN) from 3-hydroxyanthranilic acid. QUIN is an excitotoxin whose toxicity is mediated by its ability to activate glutamate N-methyl-D-aspartate receptors. Increased cerebral levels of QUIN may participate in the pathogenesis of neurologic and inflammatory disorders. HAAO has been suggested to play a role in disorders associated with altered tissue levels of QUIN. [provided by RefSeq]

Alternate Names

3-HAO, 3-hydroxyanthranilate 3,4-dioxygenase, 3-hydroxyanthranilic acid dioxygenase, EC 1.13.11.6,3-hydroxyanthranilate oxygenase, HAD, HAO

Gene Symbol

HAAO

Additional HAAO Products

Product Documents for HAAO Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for HAAO Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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