HCN3 Antibody - BSA Free

Novus Biologicals | Catalog # NBP1-81402

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
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Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: LPLSPDSPATLLARSAWRSAGSPASPLVPVRAGPWASTSRLPAPPARTLHASLSRAGRSQVSLLGPPPGGGGRRLGPRGRPLSASQPSLPQRATGDGSPGRKGSGSERLPPSGLLAKPPRTAQPPRPPVPEPATPRGLQLS

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (88%), Rat (88%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for HCN3 Antibody - BSA Free

Immunohistochemistry-Paraffin: HCN3 Antibody [NBP1-81402]

Immunohistochemistry-Paraffin: HCN3 Antibody [NBP1-81402]

Immunohistochemistry-Paraffin: HCN3 Antibody [NBP1-81402] - Staining of human liver shows no positivity in hepatocytes as expected.
Immunohistochemistry: HCN3 Antibody [NBP1-81402]

Immunohistochemistry: HCN3 Antibody [NBP1-81402]

Immunohistochemistry: HCN3 Antibody [NBP1-81402] - Staining of human duodenum shows strong cytoplasmic and membranous positivity in glandular cells.
Immunohistochemistry-Paraffin: HCN3 Antibody [NBP1-81402]

Immunohistochemistry-Paraffin: HCN3 Antibody [NBP1-81402]

Immunohistochemistry-Paraffin: HCN3 Antibody [NBP1-81402] - Staining of human duodenum shows strong membranous positivity in glandular cells.
Immunohistochemistry-Paraffin: HCN3 Antibody [NBP1-81402]

Immunohistochemistry-Paraffin: HCN3 Antibody [NBP1-81402]

Immunohistochemistry-Paraffin: HCN3 Antibody [NBP1-81402] - Staining of human kidney shows weak cytoplasmic positivity in cells in tubules.
Immunohistochemistry-Paraffin: HCN3 Antibody [NBP1-81402]

Immunohistochemistry-Paraffin: HCN3 Antibody [NBP1-81402]

Immunohistochemistry-Paraffin: HCN3 Antibody [NBP1-81402] - Staining of human pancreas shows no positivity in exocrine glandular cells as expected.

Applications for HCN3 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: HCN3

FUNCTION: Putative hyperpolarization-activated ion channel exhibiting weak selectivity for potassium over sodium ions. SUBUNIT: The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming subunits. SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein. DOMAIN: The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.

Long Name

Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3

Alternate Names

KIAA1535

Gene Symbol

HCN3

Additional HCN3 Products

Product Documents for HCN3 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for HCN3 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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