Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

FITC (Excitation = 495 nm, Emission = 519 nm)

Antibody Source

Polyclonal Sheep IgG
View all Hematopoietic Prostaglandin D Synthase/HPGDS Primary Antibodies »

Product Specifications

Immunogen

E. coli-derived recombinant human Hematopoietic Prostaglandin D Synthase/HPGDS
Pro2-Leu199
Accession # O60760

Specificity

Detects human Hematopoietic Prostaglandin D Synthase/HPGDS in direct ELISAs and Western blots.

Clonality

Polyclonal

Host

Sheep

Isotype

IgG

Applications for Hematopoietic Prostaglandin D Synthase/HPGDS Antibody [FITC]

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Hematopoietic Prostaglandin D Synthase/HPGDS

Prostaglandin D synthase catalyzes the isomerization of PGH2 to produce PGD2. Prostaglandin D synthase induces sleep, regulates nociception, inhibits platelet aggregation, and acts as an allergic mediator. Two distinct types of PGD synthase have been identified, namely the lipocalin type enzyme (b-trace) and the hematopoietic enzyme. Lipocalin type prostaglandin D synthase is localized in the central nervous system and male genital organs of various mammals and the human heart. This enzyme has been identified as b-trace, which is a major protein in human cerebrospinal fluid. Hematopoietic prostaglandin D synthase is widely distributed in the peripheral tissues and is localized in the antigen-presenting cells, mast cells, and megakaryocytes. This enzyme, which requires glutathione for activity, belongs to the sigma-class of glutathione-S-transferases.

Alternate Names

GSTS, PGDS, PTGDS2

Gene Symbol

HPGDS

Additional Hematopoietic Prostaglandin D Synthase/HPGDS Products

Product Documents for Hematopoietic Prostaglandin D Synthase/HPGDS Antibody [FITC]

Certificate of Analysis

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Product Specific Notices for Hematopoietic Prostaglandin D Synthase/HPGDS Antibody [FITC]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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