HERV Antibody - BSA Free

Novus Biologicals | Catalog # NB100-93579

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Western Blot, Block/Neutralize, In vitro assay

Cited:

Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Western Blot, Block/Neutralize, In vitro assay

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
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Product Specifications

Immunogen

Synthetic peptide corresponding to residues 42-50 [QRPGNIDAPC] of the HERV protein.

Specificity

Human Endogenous Retroviruses (HERVs), a class of multiple-sclerosis-associated retroviruses

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

59.9 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for HERV Antibody - BSA Free

Western Blot: HERV AntibodyBSA Free [NB100-93579]

Western Blot: HERV AntibodyBSA Free [NB100-93579]

Western Blot: HERV Antibody [NB100-93579] - WB detection of HERV in human placenta lysate with NB100-93579 antibody at a dilution of 1:250

Applications for HERV Antibody - BSA Free

Application
Recommended Usage

Western Blot

1:250-1:1000
Application Notes
This antibody is useful for Western Blot. Use in Immunohistochemistry-Paraffin reported in scientific literature (PMID 24635849). Use in In vitro, Immunohistochemistry-Frozen and blocking/neutralizing reported in scientific literature (PMID 26154387) The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reviewed Applications

Read 1 review rated 5 using NB100-93579 in the following applications:

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: HERV

HERVs are a class of multiple sclerosis associated retroviruses. Reacts with a replication competent Human Endogenous Retrovirus (HERVW) isolated from placenta. The synthetic peptide sequence used as immunogen is taken from the virus envelope polyprotein sequence. Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. The HERVW endogenous envelope protein has retained its original fusogenic properties and participates in trophoblast fusion during placenta morphogenesis.

Alternate Names

endogenous retroviral family W, env(C7), member 1, ENV, envelope glycoprotein, Envelope polyprotein gPr73, enverin, ENVW, env-W, HERV7Q, HERV-7q, HERV-7q Envelope protein, HERV-tryptophan envelope protein, HERV-W, HERV-W Env glycoprotein, HERV-W envelope protein, HERV-W_7q21.2 provirus ancestral Env polyprotein, HERV-W{7q21.1} provirus ancestral Env polyprotein, HERVWENV, HERV-W-ENV, HERVWenvelope protein, human endogenous retrovirus W envC7-1 envelope protein, Syncytin, syncytin A, Syncytin-1

Entrez Gene IDs

30816 (Human)

Gene Symbol

ERVW-1

UniProt

Additional HERV Products

Product Documents for HERV Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for HERV Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for HERV Antibody - BSA Free

Customer Reviews for HERV Antibody - BSA Free (1)

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  • HERV Antibody
    Name: Greta Beckerle
    Application: Immunocytochemistry
    Sample Tested: Breast cancer cells
    Species: Human
    Verified Customer | Posted 11/15/2017
    TEM imaging of T47D and MCF7 breast cancer cells.

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Protocols

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FAQs for HERV Antibody - BSA Free

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  • Q: Does the antibody recognize the HERV-W HYPER product, the digest result of the fool GENE PRODUCT HERV-W?

    A: HERV Antibody [NB100-93579] is generated against immunogen sequence QRPGNIDAPC which shares sequence homology with your mentioned sequence which was..... FTLTAPPPCRCMTSSSPYQEFLWRMQRPGNIDAPSY...... Therefore, we strongly believe that our antibody NB100-93579 will be cross-reacting with your mentioned partial protein.

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