Histone H2B [ac Lys5] Antibody (RM455)

Novus Biologicals | Catalog # NBP3-18842

Recombinant Monoclonal Antibody
Novus Biologicals
100% Guarantee

Key Product Details

Validated by

Biological Validation

Species Reactivity

Human, Vertebrate

Applications

Multiplex Immunofluorescence, Western Blot, ELISA

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # RM455 expressed in HEK293
View all Histone H2B Primary Antibodies »

Product Specifications

Immunogen

An acetyl-peptide corresponding to Histone H2B [Lys5] (Uniprot # P33778)

Modification

ac Lys5

Specificity

This antibody reacts to Histone H2B acetylated at Lysine 5. No cross reactivity with other acetylated Lysines in histones.

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Histone H2B [ac Lys5] Antibody (RM455)

Histone H2B [ac Lys5] Antibody (RM455)

Western Blot: Histone H2B [ac Lys5] Antibody (RM455) [NBP3-18842] -

Western Blot: Histone H2B [ac Lys5] Antibody (RM455) [NBP3-18842] - Western Blot of acid extracts of HeLa cells treated (+) or untreated (-) with sodium butyrate, using Clone RM455 at 0.02 ug/mL.

Applications for Histone H2B [ac Lys5] Antibody (RM455)

Application
Recommended Usage

ELISA

0.2 - 1 ug/mL

Western Blot

0.01 - 1 ug/mL

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

50% Glycerol/PBS, 1% BSA

Preservative

0.09% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C.

Background: Histone H2B

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility tothe cellular machineries which require DNA as a template. Histones thereby play a central role in transcriptionregulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set ofpost-translational modifications of histones, also called histone code, and nucleosome remodeling

Long Name

H2B Histone Family

Alternate Names

HIST1H2BK

Gene Symbol

H2BC18

Additional Histone H2B Products

Product Documents for Histone H2B [ac Lys5] Antibody (RM455)

Certificate of Analysis

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Product Specific Notices for Histone H2B [ac Lys5] Antibody (RM455)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

Epigenetics

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